Intern Med Influence of Serum Cholinesterase Levels on Patients Suspected of Having Stable Coronary Artery Disease Mito T, Takemoto M, Antoku Y, Tanaka A, Matsuo A, Hida S, Yoshitake K, Kosuga KI, Miura S.
Heart Vessels Associations between smoking habits and major adverse cardiovascular events in patients who underwent coronary computed tomography angiography as screening for coronary artery disease Higashi S, Shiga Y, Yano M, Imaizumi T, Tashiro K, Idemoto Y, Kato Y, Kuwano T, Sugihara M, Miura S.
Nutrients The Effects of Long-Term Nutrition Counseling According to the Behavioral Modification Stages in Patients with Cardiovascular Disease Matsuzaki K, Fukushima N, Saito Y, Matsumoto N, Nagaoka M, Katsuda Y, Miura S.
Cardiol Res Combination of Linagliptin and Empagliflozin Preserves Cardiac Systolic Function in an Ischemia-Reperfusion Injury Mice With Diabetes Mellitus Ideishi A, Suematsu Y, Tashiro K, Morita H, Kuwano T, Tomita S, Nakai K, Miura S.
Cardiol Res Association Between the Level of Low-Density Lipoprotein Cholesterol and Coronary Atherosclerosis in Patients Who Have Undergone Coronary Computed Tomography Angiography Inoue H, Shiga Y, Tashiro K, Kawahira Y, Suematsu Y, Idemoto Y, Tano K, Kuwano T, Sugihara M, Nishikawa H, Katsuda Y, Miura S.
FASEB J Aberrant accumulation of TMEM43 accompanied by perturbed transmural gene expression in arrhythmogenic cardiomyopathy Shinomiya H, Kato H, Kuramoto Y, Watanabe N, Tsuruda T, Arimura T, Miyashita Y, Miyasaka Y, Mashimo T, Takuwa A, Motooka D, Okuzaki D, Matsuoka K, Tsukamoto O, Hakui H, Yamada N, Lee JK, Kioka H, Kitakaze M, Takashima S, Sakata Y, Asano Y.
Hypertens Res Presence and severity of coronary artery disease in patients who achieved intensive blood pressure reduction at the time of coronary computed tomography angiography Tsukihashi Y, Shiga Y, Suematsu Y, Idemoto Y, Tashiro K, Yano Y, Kato Y, Kuwano T, Sugihara M, Miura S.
Heart Vessels Association between high-density lipoprotein cholesterol levels and major adverse cardiovascular events in patients who underwent coronary computed tomography angiography: FU-CCTA registry Kawahira Y, Shiga Y, Inoue H, Suematsu Y, Tashiro K, Kato Y, Fujimi K, Takamiya Y, Kuwano T, Sugihara M, Miura S.
Heart Vessels Differences in lesion characteristics and patient background associated with the medium-term clinical outcomes of bare-metal and first-, second- and third-generation drug-eluting stents Nakamura M , Ike A , Kato Y , Futami M , Kuwano T , Sugihara M , Iwata A , Kawamura A , Suematsu Y , Miura S.
J Clin Med Associations between High-Density Lipoprotein Functionality and Major Adverse Cardiovascular Events in Patients Who Have Undergone Coronary Computed Tomography Angiography. Inoue H, Shiga Y, Norimatsu K, Tashiro K, Futami M, Suematsu Y, Sugihara M, Nishikawa H, Katsuda Y, Miura S.
J Renin Angiotensin Aldosterone Syst Angiotensin Receptor Blocker and Neprilysin Inhibitor Suppresses Cardiac Dysfunction by Accelerating Myocardial Angiogenesis in Apolipoprotein E-Knockout Mice Fed a High-Fat Diet. Suematsu Y, Tashiro K, Morita H, Ideishi A, Kuwano T, Miura S.
Cardiometab Syndr J Apolipoprotein A-I Mimetics for Treatment of the Residual Risk of Cardiovascular Disease Miura S, Suematsu Y, Imaizumi S, Yahiro E, Kuwano T, Uehara Y, Saku K.
Cardiol J Association between mitral annulus calcification and subtypes of heart failure rehospitalization Kato Y, Arimura T, Shiga Y, Kuwano T, Sugihara M, Miura S.
Resusc Plus Comparison of clinical outcomes between patients with pulseless-ventricular tachycardia and ventricular fibrillation in out-of-hospital cardiac arrest Kato Y, Miura S, Hirayama A, Izumi C, Yasuda S, Tahara Y, Yonemoto N, Nonogi H, Nagao K, Ikeda T, Sato N, Tsutsui H, Kobayashi Y.
J Clin Med Difference in Prognosis between Continuation and Discontinuation of A 5-Month Cardiac Rehabilitation Program in Outpatients with Heart Failure with Preserved Ejection Fraction Morita H, Suematsu Y, Morita K, Yano Y, Sakamoto M, Matsuda T, Kaino K, Teshima R, Ura N, Fujita M, Tazawa R, Nakagawa H, Kitajima K, Kamada S, Fujimi K, Miura SI.
Nutrients Impact of Controlling a Nutritional Status Score on Wound Healing in Patients with Chronic Limb-Threatening Ischemia after Endovascular Treatment. Mine K, Sugihara M, Fujita T, Kato Y, Gondo K, Arimura T, Takamiya Y, Shiga Y, Kuwano T, Miura S.
PLOS GENETICS Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins Khetarpal SA, Vitali C, Levin MG, Klarin D, Park J, Pampana A, Millar JS, Kuwano T, Sugasini D, Subbaiah PV, Billheimer JT, Natarajan P, Rader DJ.
JACC Case Rep A Continuous Murmur as the Only Clinical Sign for Complex Coronary Artery Fistulas Diagnosis Imaizumi T, Takata K, Ike A, Idemoto Y, Shiga Y, Sugihara M, Matsunaga A, Miura S.
Clin Exp Hypertens Association between lipid profile and endothelial dysfunction as assessed by the reactive hyperemia index Norimatsu K, Gondo K, Kusumoto T, Motozato K, Suematsu Y, Fukuda Y, Kuwano T, Miura S.
Circ Rep Association Between Major Adverse Cardiovascular Events and the Ratio of Subcutaneous Fat Area to Visceral Fat Area in Patients Who Have Undergone Multidetector Row Computed Tomography Shibata Y, Shiga Y, Suematsu Y, Tashiro K, Kawahira Y, Morita K, Kuwano T, Sugihara M, Miura S.
J Infect Chemother Coronavirus disease (COVID-19) associated delayed-onset fulminant myocarditis in patient with a history of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection Ishikura H, Maruyama J, Hoshino K, Matsuoka Y, Yano M, Arimura T, Katano H, Kato S, Kitamura T, Nakamura Y.
2020年
Role of Nurses in Comprehensive Care for Cardiac Rehabilitation by a Multidisciplinary Team : a Questionnaire Study
Kuzuhara S*, Suematsu Y*, Yorinaga K*, Fujimi K, Kitajima K, Saku K, Nakagawa T, Miura S. 福岡大学医学紀要 2020.03 47(1)61-68
Prediction of Long-Term Outcomes in ST-Elevation Myocardial Infarction and Non-ST Elevation Myocardial Infarction with and without Creatinine Kinase Elevation-Post-Hoc Analysis of the J-MINUET Study.
Toyoda S, Sakuma M, Abe S, Inoue T, Nakao K, Ozaki Y, Kimura K, Ako J, Noguchi T, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Okamura A, Mano T, Wake M, Tanabe K, Shibata Y, Owa M, Tsujita K. Funayama H, Kokubu N, Kozuma K, Toubaru T, Saku K, Ohshima S, Miyamoto Y, Ogawa H, Ishihara M. J Clin Med. 2020.08 18;9(8):2667
Association between lipid profile and endothelial dysfunction as assessed by the reactive hyperemia index. Norimatsu K, Gondo K, Kusumoto T, Motozato K, Suematsu Y, Fukuda Y, Kuwano T, Miura S.
Clin Exp Hypertens 2020.10 1;1-6.
Low plasma apolipoprotein E-rich high-density lipoprotein levels in patients with metabolic syndrome. Shinohata R, Shiga Y, Miura S, Hirohata S, Shibakura M, Ueno-Iio T, Watanabe S, Arao Y, Usui S. Clin Chim Acta. 2020.08 510(2020)531-536
A Coronary Artery Calcium Score of Zero in Patients Who Have Undergone Coronary Computed Tomography Angiography Is Associated With Freedom From Major Adverse Cardiovascular Events. Shiga Y, Morii J, Idemoto Y, Tashiro K, Yano Y, Kato Y, Kuwano T, Sugihara M, Miura S. J Clin Med Res 2020.10 12(10):662-667
Add-on aliskiren treatment can decrease blood pressure but requires attention to risks of renal impairment and hyperkalemia Chikushi Anti-Hypertension Trial-Rasilez® (CHAT-Ras). Okamura K, Takamiya Y, Mori K, Shirai K, Urata H. Clin Exp Hypertens 2020.08.17 42(6):545-552
Elevated chymase-dependent angiotensin II-forming activity in circulating mononuclear leukocytes was observed in the patient of atrial fibrillation. Okamura K, Okuda T, Takamiya Y, Shirai K, Urata H. Heart Vessels 2020.08 35(8):1116-1124
A Patient with Bilateral Primary Aldosteronism Refractory to Oral Eplerenone Who Responded to Esaxerenone with Increased Renin Activity. Okamura K, Matsushima M, Yamamoto F, Takamiya Y, Okuda T, Shirai K, Okamura K, Urata H. Am J Case Rep 2020.01.07 doi
Inappropriate direct oral anticoagulant dosing in atrial fibrillation patients is associated with prescriptions for outpatients rather than inpatients: a single-center retrospective cohort study. Miyazaki M, Matsuo K, Uchiyama M, Nakamura Y, Sakamoto Y, Misaki M, Tokura K, Jimi S, Okamura K, Adachi S, Yamamoto T, Shirai K, Urata H, Imakyure O. J Pharm Health Care Sci 2020.02.11 doi
Comprehensive Efficacy of the Dipeptidyl Peptidase 4 Inhibitor Alogliptin in Practical Clinical Settings: A Prospective Multi-Center Interventional Observational Study. Takamiya Y, Kobayashi K, Kudo T, Okuda T, Okamura K, Shirai K, Urata H. J Clin Med Res 2020.07 12(7):423-430
Influence of Serum Cholinesterase Levels on Patients Suspected of Having Stable Coronary Artery Disease Mito T, Takemoto M, Antoku Y, Tanaka A, Matsuo A, Hida S, Yoshitake K, Kosuga K, Miura S. Intern Med. 2020.11.16 5719-20
Sacubitril/Valsartan Inhibits Cardiomyocyte Hypertrophy in Angiotensin II-Induced Hypertensive Mice Independent of a Blood Pressure-Lowering Effect Tashiro K, Kuwano T, Ideishi A, Morita H, Idemoto Y, Goto M, Suematsu Y, Miura S. Cardiol Res 2020.11.02 11(6):376-385
Associations between smoking habits and major adverse cardiovascular events in patients who underwent coronary computed tomography angiography as screening for coronary artery disease Higashi S, Shiga Y, Yano M, Imaizumi T, Tashiro K, Idemoto Y, Kato Y, Kuwano T, Sugihara M, Miura S. Heart Vessels 2020.11.27
Effects of Phase II Comprehensive Cardiac Rehabilitation on Risk Factor Modification and Exercise Capacity in Patients With Acute Coronary Syndrome-Results From the JACR Registry- Nishitani-Yokoyama M, Daida H, Shimada K, Ushijima A, Kida K, Kono Y, Sakata Y, Nagayama M, Furukawa Y, Fukuma N, Saku K, Miura S, Ohya Y, Goto Y, Makita S. Circ Rep. 2020.12 715-721
Associations Between High Levels of High-Density Lipoprotein Cholesterol and the Presence and Severity of Coronary Artery Disease in Patients Who Have Undergone Coronary Computed Tomography Angiography Tashiro K, Inoue H, Shiga Y, Tsukihashi Y, Imaizumi T, Norimatsu K, Idemoto Y, Kuwano T, Sugihara M, Nishikawa H, Katsuda Y, Miura S. J Clin Med Res. 2020.11 12(11):734-739
Efficacy of Super Slow Inflation as Lesion Preparation for Drug-Coated Balloons in Femoropopliteal Lesions Sugihara M, Mine K, Futami M, Kato Y, Arimura T, Yano M, Takamiya Y, Kuwano T, Miura S. Circ Rep 2020.10.16 2(11):682-690
A Strict Target for Low-Density Lipoprotein Cholesterol May not Be Necessary for Secondary Prevention of Cardiovascular Disease in All Elderly Patients With Dyslipidemia Miura S, Katsuda Y, Sugihara M, Ike A, Nishikawa H, Kawamura A. Cardiol Res 2020.12 11(6):366-369
Associations between the psoas major muscle index and the presence and severity of coronary artery disease Imaizumi T , Shiga Y , Idemoto Y , Tashiro K , Ueda Y , Miyase Yano Y , Norimatsu K , Nakamura A , Kuwano T , Iwata A , Miura S. Medicine (Baltimore) 2020.07.10 99(28): e21086
Association Between the Level of Low-Density Lipoprotein Cholesterol and Coronary Atherosclerosis in Patients Who Have Undergone Coronary Computed Tomography Angiography Inoue H , Shiga Y , Tashiro K , Kawahira Y , Suematsu Y , Idemoto Y , Tano T, Kuwano T , Sugihara M , Nishikawa H , Katsuda Y, Miura S. Cardiol Res 2020.12.11 12(1):10-15
Regression and Stabilization of Coronary Vulnerable Plaque by Evolocumab as Assessed by Multidetector Row Computed Tomography Shiga Y , Idemoto Y , Tashiro K , Imaizumi T , Ueda Y , Yano Y , Norimatsu K , Nakamura A , Miura S. Intern Med. 2020.10.01 59(19):2391-2395
ILRUN, a Human Plasma Lipid GWAS Locus, Regulates Lipoprotein Metabolism in Mice Bi X , Kuwano T , Lee PC , Millar JS , Li L , Shen Y , Soccio RE , Hand NJ , Rader DJ . Circ Res 2020.11 127(11):1347-1361
Changes in serum levels of angiopoietin-like protein-8 and glycosylphosphatidylinositol-anchored high-density lipoprotein binding protein 1 after ezetimibe therapy in patients with dyslipidemia Ideishi A , Suematsu Y , Tashiro K , Morita H , Kumagai-Koyanagi N , Kuwano T , Miura S. Clin Chim Acta. 2020.11 510:675-680
Reactive Hyperemia Index Associated With Atherosclerotic Cardiovascular Disease Under Treatment for Lifestyle Diseases Motozato K , Suematsu Y , Norimatsu K , Kusumoto T , Miura SI. J Clin Med Res 2020.05 12(5):293-299
Postural Conversion Computed Tomography for the Diagnosis of Pneumopericardium due to Perforation by the Active Atrial Lead: A Case Report. Futami M, Komaki T, Arinaga T, Morii J, Sugihara M, Ogawa M, Miura SI. Intern Med. 2020.02.15 59(4):541-544.
Gap-related Pulmonary Vein and Left Atrial Flutter Mimicking Cavotricuspid Isthmus-dependent Atrial Flutter Komaki T, Ogawa M* Idemoto Y, Morii J, Saku K, Miura SI. Intern Med. 2020.05.05 59;1413-1416.
A Rare Case of Submassive Pulmonary Embolism With a Right Aberrant Subclavian Artery and Thrombosed Kommerell Diverticulum. Onishi N*, Komaki T*, Nakamura M, Arimura T, Morii J, Ogawa M, Miura S. Intern Med. 2020.04.23 59(15):1861-1865
Endoscopic Findings of an Excessively Compressed Interwoven Nitinol Supera Stent Sugihara M , Miura SI. Cric J. 2020.01.24 84(5):830
Successful case of direct puncture of a prosthetic bypass graft in endovascular treatment for long superficial artery chronic total occlusion: a case report Sugihara M , Ueda Y , Yano Y , Miura SI . Eur Heart J Case Rep 2020.11 4(6):1-5
A Strict Target for Low-Density Lipoprotein Cholesterol May not Be Necessary for Secondary Prevention of Cardiovascular Disease in ALL Elderly Patients With Dyslipidemia Miura S, Katsuda Y, Sugihara M, Ike A, Nishikawa H, Kawamura A. Cardiol Res 2020.11 11(6):366-369
Kuzuhara S*, Suematsu Y*, Yorinaga K*, Fujimi K, Kitajima K, Saku K, Nakagawa T, Miuta S.Role of Nurses in Comprehensive Care for Cardiac Rehabilitation by a Multidisciplinary Team : a Questionnaire Study.福岡大学医学紀要.2020.47(1)61-68
Motoki Yamashita, Tomo Komaki, Kohei Tashiro, Yuki Inada, Atsushi Iwata, Masahiro Ogawa, Eriko Morishita, Shin-ichiro Miura Hereditary Antithrombin Deficiency Presenting with Deep Venous Thrombosis During the Second Pregnancy. Intern Med. 2020 Jan 15;59(2):235-239.
2019年
Nose D, Shiga Y, Ueda Y, Idemoto Y, Tashiro K, Suematsu Y, Kuwano T, Kitajima K, Saku K, Miura S.Association between plasma levels of PCSK9 and the presence of coronary artery disease in Japanese.Heart and Vessels.2019.34(1):19-28
Okamura K, Urata H.Simplifying Adrenal Vein Sampling for Cardialogists “New Era of Catheter Treatment for Hypertension”.Hypertension Research.2019.42;117-119
Imaizumi S, Shiga Y, Ogawa M, Sako H, Nagata Y, Matsunaga A, Shirotani T, Hoshino F, Yahiro E, Uehara Y, Morito N, Tanigawa H, Shimono D, Fukushima M, Sugihara H, Norimatsu K, Kusumoto T, Saku K, Miura SI.Randomized trial of an increased dose of calcium channel blocker or angiotensin II type 1 receptor blocker as an add-on intensive depressor therapy in type 2 diabetes mellitus patients with uncontrolled essential hypertension: the ACADEMIE Study.Heart Vessels. 2019.34(4):698-710
Nose D, Shiga Y, Ueda Y, Idemoto Y, Tashiro K, Suematsu Y, Kuwano T, Kitajima K, Saku K, Miura SI.Association between plasma levels of PCSK9 and the presence of coronary artery disease in Japanese.Heart Vessels. 2019.34(1):19-28
Shigemoto E, Iwata A, Futami M, Kato Y, Yamashita M, Imaizumi S, Kuwano T, Ike A, Sugihara M, Saku K, Miura SI.Influence of chronic kidney disease on coronary plaque components in coronary artery disease patients with both diabetes mellitus and hypertension.Heart Vessels.2019.3. doi
Yamamoto T, Miura SI, Shirai K, Urata H.Renoprotective Benefit of Tolvaptan in Acute Decompensated Heart Failure Patients With Loop Diuretic-Resistant Status.J Clin Med Res. 2019.11(1):49-55
Shishikura D, Kataoka Y, Honda S, Takata K, Kim SW, Andrews J, Psaltis PJ, Sweeney M, Kulikowski E, Johansson J, Wong NCW, Nicholls SJ.The Effect of Bromodomain and Extra-Terminal Inhibitor Apabetalone on Attenuated Coronary Atherosclerotic Plaque: Insights from the ASSURE Trial.Am J Cardiovasc Drugs.2019.19(1):49-57
Shishikura D, Kataoka Y, Honda S, Takata K, Kim SW, Andrews J, Psaltis PJ, Sweeney M, Kulikowski E, Johansson J, Wong NCW, Nicholls SJ.Associations of ABCG1-mediated Cholesterol Efflux Capacity with Coronary Artery Lipid Content Assessed by Near-Infrared Spectroscopy.Cardiovasc Diagn Ther.2019.in press
Okamura K, Okuda T, Fukuda Y, Takamiya Y, Shirai K, Miyajima S, Ishii T, Urata H.A Case of Primary Aldosteronism Due to A Primary Adrenal Adenoma Diagnosed by Segmental Adrenal Venous Sampling (S-AVS) Using a Modified Catheter System and Lateral Cine Angiography.Am J Case Rep.2019.2;20:139-145
Okamura K, Shirai K, Miyazaki M, Okuda T, Takamiya Y, Goto M, Urata H.Investigation of a Dipeptidyl Peptidase-4 Inhibitor/Thiazolidinedione Combination Drug for Patients With Type 2 Diabetes and Poor Glycemic Control: Difficulty With Patient Enrollment.J Clin Med Res. 2019.11(2):89-97
Takamiya Y, Okamura K, Shirai K, Okuda T, Kobayashi K, Urata H.Multicenter prospective observational study of teneligliptin, a selective dipeptidyl peptidase-4 inhibitor, in patients with poorly controlled type 2 diabetes: Focus on glycemic control, hypotensive effect, and safety Chikushi Anti-Diabetes Mellitus Trial-Teneligliptin (CHAT-T).Clin Exp Hypertens.2019.11:1-8
Otsu Y, Kai M, Suematsu Y, Kiyomi F, Saku K, Kamimura H, Miura SI.Assessment of inter-rater agreement between physicians and their patients regarding medication adherence in a clinical questionnaire study.Medicine (Baltimore).2019.98(18):e15188
Sakai T, Miura S.Effects of Sodium-Glucose Cotransporter 2 Inhibitor on Vascular Endothelial and Diastolic Function in Heart Failure With Preserved Ejection Fraction -Novel Prospective Cohort Study-.Circulation Reports.2019.1(7):286-295
Yamamoto T, Shirai K, Okamura K, Urata H.Two Years Efficacy of Paclitaxel-Coated Balloon Dilation for In-Stent Renal Artery Restenosis Due to Takayasu Arteritis.American Journal of Case Reports.2019.20:1089–1093
Satou S, Okamura K, Konishi R, Shirai K, Urata H.Observation of renal sympathetic nerves by intravascular ultrasound.Hypertens Res. 2019.42(7):1092-1094
Okamura K, Okuda T, Shirai K, Urata H.Increase of chymase-dependent angiotensin II-forming activity in circulating mononuclear leukocytes after acute myocardial infarction chymase activity after acute myocardial infarction.Heart Vessels. 2019.34(7):1148-1157
Suematsu Y, Zhang B, Kuwano T, Sako H, Ogawa M, Yonemoto N, Nonogi H, Kimura T, Nagao K, Yasunaga S, Saku K, Miura S.Citizen bystander-patient relationship and 1-month outcomes after out-of-hospital cardiac arrest of cardiac origin from the All-Japan Utstein Registry : a prospective , nationwide , population-based , observational study.BMJ Open.2019.26;9(7)
Suematsu Y, Kawachi E, Idemoto Y, Matsuo Y, Kuwano T, Kitajima K, Imaizumi S, Kawamura A, Saku K, Uehara Y, Miura SI.Anti-atherosclerotic effects of an improved apolipoprotein A-I mimetic peptide.International Journal of Cardiology.2019.doi: 10.1016
Okamura K, Okuda T, Takamiya Y, Shirai K, Urata H.High Fib4 index in patients with suspected NASH is associated with elevation of chymase-dependent angiotensin II-forming activity in circulating mononuclear leucocytes.Heart Vessels.2019.34(9):1559-1569
Tano K, Suematsu Y, Tashiro K, Kumagai-Koyanagi N, Matsuo Y, Kuwano T, Miura S+I. ; Zenith Trial Investigators.Ezetimibe Monotherapy Reduces Serum Levels of Platelet-Activating Factor Acetylhydrolase in Patients With Dyslipidemia.J Clin Med Res.2019.11(10):676-681
Fujimi K, Imaizumi T, Suematsu Y, Kitajima K, Ueda T, Ishida T, Futami M, Ujifuku Y, Matsuda T, Sakamoto M, Horita T, Teshima R, Kaino K, Fujita M, Arimura T, Shiga Y, Shiota E, Miura SI.Differential prognostic impact between completion and non-completion of a 5-month cardiac rehabilitation program in outpatients with cardiovascular diseases.International Journal of Cardiology.2019.15;297:111-117
Matsuo Y, Suematsu Y, Idemoto Y, Kuwano T, Kitajima K, Miura SI.Changes in the function of angiotensin II type 1 receptor due to cholesterol depletion from cell membrane.Biochemical Biophysical Research Communications.2019.514(3):791-797
Norimatsu K, Kusumoto T, Yoshimoto K, Tsukamoto M, Kuwano T, Nishikawa H, Matsumura T, Miura SI.Importance of measurement of the diameter of the distal radial artery in a distal radial approach from the anatomical snuffbox before coronary catheterization.Heart Vessels. 2019.34(10):1615-1620
Kitajima K, Fujimi K, Matsuda T, Fujita M, Kaino K, Teshima R, Ujifuku Y, Horita T, Sakamoto M, Arimura T, Shiga Y, Shiota E, Miura SI.Possibility of Cardio-renal Protection by Long-term Cardiac Rehabilitation in Elderly Patients with Cardiovascular Diseases.Internal Medicine.2019.58(24):3613
Suematsu Y, Goto M, Park C, Nunes ACF, Jing W, Streja E, Rhee CM, Cruz S, Kashyap ML, Vaziri ND, Narayanaswami V, Kalantar-Zadeh K, Moradi H.Association of Serum Paraoxonase/Arylesterase Activity With All-Cause Mortality in Maintenance Hemodialysis Patients.The Journal of Clinical Endocrinology & Metabolism.2019.104(10):4848-4856
Goto M, Suematsu Y, Nunes ACF, Jing W, Khazaeli M, Lau WL, Vaziri ND.Ferric Citrate Attenuates Cardiac Hypertrophy and Fibrosis in a Rat Model of Chronic Kidney Disease.Iranian Journal of Kidney Diseases.2019.13(2):98-104
2018年
Devarajan S, Yahiro E, Uehara Y, Kuroda R, Hirano Y, Nagata K, Miura S, Saku K, Urata H. Depressor effect of the young leaves of Polygonum hydropiper Linn. in high-salt induced hypertensive mice.Biomedicine & Pharmacotherapy.2018.102(2018)1182-1187
Shiiba M, Zhang B, Miura SI, Ike A, Nose D, Kuwano T, Imaizumi S, Sugihara M, Iwata A, Nishikawa H, Kawamura A, Shirai K, Yasunaga S, Saku K.Correction to: Association between discordance of LDL-C and non-HDL-C and clinical outcomes in patients with stent implantation: from the FU-Registry.Heart Vessels.2018.Epub ahead of print
Hashimoto T, Ako J, Nakao K, Ozaki Y, Kimura K, Noguchi T, Yasuda S, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Uematsu M, Hirata K, Tanabe K, Shibata Y, Owa M, Tsujita K, Funayama H, Kokubu N, Kozuma K, Uemura S, Toubaru T, Saku K, Ohshima S, Nakai M, Nishimura K, Miyamoto Y, Ogawa H, Ishihara M; J-MINUET investigators.A lower eicosapentaenoic acid/arachidonic acid ratio is associated with in-hospital fatal arrhythmic events in patients with acute myocardial infarction: a J-MINUET substudy.Heart Vessels.2018.33(5):481-488
Koyoshi R, Shiga Y, Idemoto Y, Ueda Y, Tashiro K, Kuwano T, Kitajima K, Fujimi K, Kawamura A, Ogawa M, Miura S.Safety of Landiolol Hydrochloride as a Premedication for Producing an Appropriate Heart Rate for Multidetector-Row Computed Tomography Coronary Angiography.J Clin Med Res.2018.10(1):22-26
Shiiba M, Zhang B, Miura S, Ike A, Nose D, Kuwano T, Imaizumi S, Sugihara M, Iwata A, Nishikawa H, Kawamura A, Shirai K, Yasunaga S, Saku K.Association between discordance of LDL-C and non-HDL-C and clinical outcomes in patients with stent implantation: from the FU-Registry.Heart Vessels.2018.33(2):102-112
Morito N, Suematsu Y, Koyoshi R, Shiga Y, Kuwano T, Iwata A, Fujimi K, Kawamura A, Miura S.The Current Conditions and Lifestyles of Obese University Students.J Clin Med Res.2018.10(3):240-246
Suematsu Y, Jing W, Nunes A, Kashyap M, Khazaeli M, Vaziri ND, Morade H.LCZ696(Sacubitril/valsartan)an Angiotensin-Receptor Neprilysin Inhibitor , Atteniates Cardiac Hypertrophy , Fibrosis , and Vasculopathy in a Rat Model of Chronic Kidney Disease.Journal of Cardiac Failure.2018.Vol.24 No.4
Lau WL, Vaziri ND, Nunes A, Comeau AM, Langilie M, England W, Khazaeli M, Suematsu Y, Phan J, Whiteson K.The phosphate binder ferric citrate alters the gut microbiome in rates with chronic kidney disease.JPET.2018.367(3):452-460
Okamura K, Shirai K, Okuda T, Urata H.The Prevalence of Japanese Outpatients with Hypertension Who Meet the Definition of Treatment Resistant Hypertension and Are Eligible for Enrolment in Clinical Trials of Endovascular Ultrasound Renal Denervation.Intern Med. 2018.57(1):1-12
Okamura K, Okuda T, Shirai K, Abe I, Kobayashi K, Ishii T, Haraoka S, Urata H.Persistent Primary Aldosteronism Despite Iatrogenic Adrenal Hemorrhage After Adrenal Vein Sampling.J Clin Med Res.2018.10(1):66-71
Okamura K, Shirai K, Okuda T, Urata H.Improvement of Diurnal Blood Pressure Variation by Azilsartan.J Clin Med Res. 2018.10(1):41-49
Okamura K, Urata H.Anticipated expansion of a new approach to treating hypertension without medication by catheter-based renal denervation.Journal of Thoracic Disease.2018.10(26):3266-3270
Okamura K, Satou S, Setojima K, Shono S, Miyajima S, Ishii T, Shirai K, Urata H.Reduction of Blood Pressure Following After Renal Artery Adventitia Stripping During Total Nephroureterectomy: Potential Effect of Renal Sympathetic Denervation.Am J Case Rep. 2018.19:567-572
Okuda T, Okamura K, Shirai K, Urata H.Effect of Angiotensin-Converting Enzyme Inhibitor/Calcium Antagonist Combination Therapy on Renal Function in Hypertensive Patients With Chronic Kidney Disease: Chikushi Anti-Hypertension Trial - Benidipine and Perindopril.J Clin Med Res. 2018.10(2):117-124
Okamura K, Shirai K, Totake N, Okuda T, Urata H.Positive correlation between blood pressure or heart rate and chymase-dependent angiotensin receptor blockers and amlodipine.Clin Exp Hypertens.2018.40(2):112-117
Okamura K, Shirai K, Totake N, Okuda T, Urata H.Prospective direct comparison of antihypertensive effect and safety between high-dose amlodipine or indapamide in hypertensive patients uncontrolled by standard doses of angiotensin receptor blockers and amlodipine.Clin Exp Hypertens.2018.40(2):99-106
Shelton RS, Ogawa M, Lin H, Shen C, Wong J, Lin SF, Chen PS, Everett TH.Effects of Stellate Ganglion Cryoablation on Subcutaneous Nerve Activity and Atrial Tachyarrhythmias in a Canine Model of Pacing-Induced Heart Failure.JACC Clin Electrophysiol.2018.4(5):686-695
Piccirillo G, Magri D, Alessandro G, Fiorucci C, Moscucci F, Iorio CD, Mastropietri F, Parrotta I, Ogawa M, Lin SF, Chen PS.Oscillatory behavior of P wave duration and PR interval in expermental congestive heart failure : a preliminary study.Physiological Measurement.2018.39(3)
Kato Y, Iwata A, Futami M, Yamashita M, Imaizumi S, Kuwano T, Ike A, Sugihara M, Nishikawa H, Zhang B, Yasunaga S, Saku K, Miura SI.Impact of von Willebrand factor on coronary plaque burden in coronary artery disease patients treated with statins.Medicine (Baltimore). 2018.97(17):e0589
Yamashita M, Iwata A, Kato Y, Futami M, Imaizumi S, Kuwano T, Ike A, Sugihara M, Nishikawa H, Zhang B, Yasunaga S, Saku K, Miura SI.Impact of the triglyceride level on coronary plaque components in female patients with coronary artery disease treated with statins.Heart Vessels.2018.33(10):1175-1184
Matsuo Y, Suematsu Y, Tomita S, Tashiro K, Kuwano T, Kitajima K, Miura SI.Unique mode of binding between angiotensin II type 1 receptor and its blockers.Clin Exp Hypertens.2018.19:1-6
Nakanishi J, Suematsu Y, Arimura T, Kuwano T, Shiga Y, Kitajima K, Morito N, Nii T, Saku K, Miura SI.Recommendations of Lifestyle Modification According to a Survey of First-Year University Students.J Clin Med Res.2018.10(10):772-780
Kamizono Y, Shiga Y, Suematsu Y, Imaizumi S, Tsukahara H, Noda K, Kuwano T, Fujimi K, Saku K, Miura SI.Impact of cigarette smoking cessation on plasma α-klotho levels.Medicine (Baltimore).2018.97(35):e11947
Shishikura D, Sidharta SL, Honda S, Takata K, Kim SW, Andrews J, Montarello N, Delacroix S, Baillie T, Worthley MI, Psaltis PJ, Nicholls SJ.The relationship between segmental wall shear stress and lipid core plaque derived from near-infrared spectroscopy. Atherosclerosis.2018.275:68-73
Takata K, Kataoka Y, Andrews J, Puri R, Hammadah M, Duggal B, Kapadia SR, Tuzcu EM, Nissen SE, Nicholls SJ.Triglyceride-to-High-Density Lipoprotein Cholesterol Ratio and Vulnerable Plaque Features With Statin Therapy in Diabetic Patients With Coronary Artery Disease: Frequency-Domain Optical Coherence Tomography Analysis. JACC Cardiovasc Imaging.2018.11(11):1721-1723
Nose D, Hori M, Miyamoto Y, Imaizumi S, Harada-Shiba M, Saku K, Miura SI.Discontinuation of LDL apheresis with evolocumab in an FH patient with a duplication of exon 2-6 in the LDLR gene.Journal of Cardiology Cases.2018.19(2):55-58
Okamura K, Kuroda R, Nagata K, Urata H.Prospective single-arm observational study of human chymase inhibitor Polygonum hydropiper L in subjects with hypertension.Clin Exp Hypertens. 2018.23:1-9
2017年
Miyamoto S, Yotsumoto F, Ueda T, Fukami T, Sanui A, Miyata K3, Nam S, Fukagawa S, Katsuta T, Maehara M, Kondo H, Miyahara D, Shirota K, Yoshizato 6, Kuroki M, Nishikawa H, Saku K, Tsuboi Y, Ishitsuka K, Takamatsu Y, Tamura K, Matsunaga A, Hachisuga T, Nishino S, Odawara T, Maeda K, Manabe S, Ishikawa T, Okuno Y13, Ohishi M, Hikita T, Mizushima H, Iwamoto R, Mekada E. BK-UM in patients with recurrent ovarian cancer or peritoneal cancer: a first-in-human phase-I study.BMC Cancer.2017.01.17(1):89
Norimatsu K*, Kuwano T*, Miura S,Shimizu T, Shiga Y, Suematsu Y, Miyase Y, Adachi S, Nakamura A, Imaizumi S, Iwata A, Nishikawa H, Uehara Y, Saku K.Significance of the percentage of cholesterol efflux capacity and total cholesterol efflux capacity in patients with or without coronary artery disease.Heart Vessels.2017.01.32(1):30-38
Shiga Y, Miura S, Motozato K, Yoshimine Y, Norimatsu K, Arimura T, Koyoshi R, Morii J, Kuwano T, Inoue K, Shirotani T, Fujisawa K, Matsunaga E, Saku K.Efficacy and Safety of Combination Therapy Consisting of Angiotensin II Type 1 Receptor Blocker, Calcium Channel Blocker and Hydrochlorothiazide in Patients With Hypertension.J Clin Med Res.2017.02.9(2):98-103
Ueda T, Noda K, Kiyomi, Yanase T, Saku K.Follow-up to the STYLIST study (Lifestyle Changes Through the Use of Delivered Meals and Dietary Counseling):the STYLIST EXTENSION study.福岡大学医学紀要.2017.0344(1):7-14
Komaki T, Miura S, Arimura T, Shiga Y, Morii J, Kuwano T, Imaizumi S, Kitajima K, Iwata A, Morito N, Yahiro E, Fujimi K, Matsunaga A, Saku K.The Change in Body Weight During Hospitalization Predicts Mortality in Patients With Acute Decompensated Heart Failure.J Clin Med Res.2017.03.9(3):200-206
Matsumoto N, Ogawa M, Morii J, Nagata Y, Imaizumi S, Matsunaga A, Saku K.Successful Catheter Ablation of Two Distinct Premature Ventricular Complexes Arising from Right Ventricular Outflow Tract Guided by EnSite NavX 3-D Mapping System with Multielectrode Basket Catheter.福岡大学医学紀要.2017.03.44(1):35-40
Gondo K, Ike A, Ogawa M, Shirai K, Sugihara M, Nishikawa H, Iwata A, Kawamura A, Mori K, Zhang B, Miura S, Yasunaga S, Saku K.Is Bare-metal Stent Still Useful for Improving Outcomes of Percutaneous Coronary Intervention?:From the FU-Registry.Journal of Cardiology.2017.04.69(4):652-659
Ishida T, Miura S, Fujimi K, Futami M, Ueda Y, Ueda T, Arimura T, Koyoshi R, Shiga Y, Kitajima K, Saku K.Significance of Cardiac Rehabilitation on Visit-to-Visit Variability of Blood Pressure in Patients With Cardiovascular Disease in a 12-Month Follow-Up.J Clin Med Res.2017.04.9(4):345-352
Adachi S, Miura S, Shiga Y, Arimura T, Morii J, Kuwano T, Kitajima K, Iwata A, Morito N, Fujimi K, Yahiro E, Nishikawa H, Saku K.Effects of Tolvaptan With or Without the Pre-Administration of Renin-Angiotensin System Blockers in Hospitalized Patients With Acute Decompensated Heart Failure.Int Heart J.2017.05.58(3):385-392
Shiga Y, Miura S, Motozato K, Norimatsu K, Yano M, Hitaka Y, Adachi S, Kuwano T, Inoue K, Inoue A, Fujisawa K, Shirotani T, Kusumoto T, Ideishi M, Saku K.Comparison of Efficacy and Safety of Azilsartan and Olmesartan in Patients With Essential Hypertension.Int Heart J.2017.05.58(3):416-421
Kato Y, Iwata A, Nakamura M, Miura S, Saku K.In-Stent Restenosis due to Stent Recoil After Third-Generation Drug-Eluting Stent Implantation.J Clin Med Res.2017.06.9(6):534-538
Arinaga T, Komaki T, Miura S, Futami M, Morii J, Sugihara M, Saku K. A rare case of eosinophilic granulomatosis with polyangiitis complicated with progressive pericardial effusion. Journal of Cardiology Cases. 2017.05.15(5):163-166
Komaki T, Miura S, Gondo K, Nakamura A, Ike A, Matsunaga A, Saku K. A rare case of acute myocardial infarction with a non-specific symptom in a young female with systemic lupus erythematosus. Journal of Cardiology Cases. 2017.08.16(2):56-61
Komaki T, Urata H, Mori K, Iwashita A, Ikeda K, Haraoka S. A Rare Case of Biphasic Malignant Peritoneal Mesothelioma with Refractory Ascites. Internal Medicine. 2017. 56(7):861-864
Ueda Y, Shiga Y, Idemoto Y, Tashiro K, Motozato K, Koyoshi R, Kuwano T, Fujimi K, Ogawa M, Saku K, Miura S.Association between the presence or severity of coronary artery disease and pericardial fat, paracardial fat, epicardial fat, visceral fat and subcutaneous fat as assessed by multi-detector row computed tomography.Int Heart J. 2017.in press
Matsuoka Y, Ike A, Ogawa M Gondo K, Shirai K, Sugihara M, Nose D, Nishikawa H, Iwata A, Kawamura A, Mori K, Zhang B, Yasunaga S, Miura S, Saku K.Sex difference between target levels of cholesterol-related parameters and post-PCI long-term clinical outcomes: from the FU-Registry.J Cardiol. 2017.71(2018)259-267
Hasegawa K, Kawachi E, Uehara Y, Yoshida T, Imaizumi S, Ogawa M, Miura S, Saku K.Improved 68 Ga-labeling method using ethanol addition: Application to the α-helical peptide DOTA-FAMP.J Labelled Comp Radiopharm.2017.60(1):55-61
Miura S.Acute Coronary Syndrome With or Without Heterozygous Familial Hypercholesterolemia.Int Heart J.2017.58(1):1-2
Idemoto Y, Miura S, Norimatsu K, Suematsu Y, Hitaka Y, Shiga Y, Morii J, Imaizumi S, Kuwano T, Iwata A, Zhang B, Ogawa M, Saku K.Evaluation of the antithrombotic abilities of non-vitamin K antagonist oral anticoagulants using the Total Thrombus-formation Analysis System®.Heart Vessels.2017.32(3):309-316
Kuwano T, Miura S, Norimatsu K, Arimura T, Shiga Y, Tomita S, Nakayama A, Matsuo Y, Imaizumi S, Saku K.Advanced glycation of high-density lipoprotein and the functionality of aldosterone release in type 2 diabetes.Hypertens Res.2017.40(3):271-276
Gondo K, Ike A, Ogawa M, Shirai K, Sugihara M, Nishikawa H, Iwata A, Kawamura A, Mori K, Zhang B, Miura S, Yasunaga S, Saku K*.Is a bare-metal stent still useful for improving the outcome of percutaneous coronary intervention? From the FU-Registry.Journal of Cardiology.2017.69(4):652-659
Oginosawa Y, Kohno R, Honda T, Kikuchi K, Nozoe M, Uchida T, Minamiguchi H, Sonoda K, Ogawa M, Ideguchi T, Kizaki Y, Nakamura T, Oba K, Higa S, Yoshida K, Tsunoda S, Fujino Y, Abe H.Superior Rhythm Discrimination With the SmartShock Technology Algorithm - Results of the Implantable Defibrillator With Enhanced Features and Settings for Reduction of Inaccurate Detection (DEFENSE) Trial.Circ J.2017.81(9):1272-1277
Kato Y, Iwata A, Zhang B, Miura S, Imaizumi S, Kuwano T, Ike A, Sugihara M, Nishikawa H, Yasunaga S, Saku K.Effects of dipeptidyl peptidase-4 inhibitor sitagliptin on coronary atherosclerosis as assessed by intravascular ultrasound in type 2 diabetes mellitus with coronary artery disease.IJC Metab Endocr.2017.16:1-9
Futami M, Fujimi K, Ueda T, Matsuda T, Fujita M, Kaino K, Sakamoto M, Horita T, Koyoshi R, Arimura T, Shiga Y, Kuwano T, Kitajima K, Saku K, Miura S.Cardiac rehabilitation in patients with cardiovascular disease leads various hemodynamic parameters obtained using simple non-invasive tests to their appropriate levels.Int J Cardiol Heart Vasc.2017.17:23-29
Sako H, Miyazaki M, Suematsu Y, Koyoshi R, Shiga Y, Kuwano T, Kitajima K, Iwata A, Yorinaga K, Fujimi K, Miura S.A Case of Multifaceted Assessment in an Elderly Patient With Acute Decompensated Heart Failure.Cardiol Res.2017.8(6):339-343
Jing W, Vaziri ND, Nunes A, Suematsu Y, Farzaneh T, Khazaeli M, Morade H.LCZ696(Sacubitril/valsartan)ameliorates ameliorates oxidative stress , inflammation , fibrosis and improves renal function beyond angiotensin receptor blockade in CKD.Am J Transl Res.2017.9(12):5473-5484
Suematsu Y, Obi Y, Shimomura A, Alizadeh RF, Vaziri ND, Ngiyen NT, Stamos MJ, Ichii H.Risk of Postoperative Venous Thromboembolism Among Pregnant Woman.The American Journal of Cadiology.2017.120(3):479-483
Sakai T, Miura S.Effect of sodium-glucose cotransporter 2 inhibitor on vascular endothelial function and diastolic function in pastients with heart failure with preserved ejection fraction (HFpEF).Circulation.2017.136:A17041
2016年
Tei C, Imamura T, Kinugawa K, Inoue T, Masuyama T, Inoue H, Noike H, Muramatsu T, Takeishi Y, Saku K, Harada K, Daida H, Kobayashi Y, Hagiwara N, Nagayama M, Momomura S, Yonezawa K, Ito H, Gojo S, Akaishi M, Miyata M, Ohishi M. Waon Therapy for Managing Chronic Heart FailureCirculation. Journal.2016.80(4):827-34
Kumagai N, Ogawa M, Zhang B, Koyoshi R, Morii J, Yasuda T, Matsumoto N, Matsuo K, Saku K.Paradoxical nocturnal elevation of sympathetic tone and spontaneous ventricular fibrillation in Brugada syndrome. Journal of Cardiology.2016.67(3):229-235
Arimura T, Miura S, Morito N, Shiga Y, Kitajima K, Morii J, Iwata A, Fujimi K, Yahiro E, Saku K.Recent Patient Characteristics and Medications at Admission and Discharge in Hospitalized Patients With Heart Failure. Journal of Clinical Medicine Research.2016.8(2):97-104
Takata K, Imaizumi S, Kawachi E, Yahiro E, Suematsu Y, Shimizu T, Abe S, Matsuo Y, Nakajima K, Yasuno T, Jimi S, Zhang B, Uehara Y, Miura S, Saku K.The ApoA-I mimetic peptide FAMP promotes recovery from hindlimb ischemia through a nitric oxide (NO)-related pathway.International Journal of Cardiology.2016.15(207):317-325
Goto M, Miura S, Yamamoto T, Fukuda Y, Kuwano T, Kimura I, Sanui A, Miyamoto S, Saku K.Anticoagulant Therapy in a Pregnant Woman with May-Thurner Syndrome. Internal Medicine.2016.55(1):59-62
Suematsu Y, Miura S, Takata K, Shimizu T, Kuwano T, Imaizumi S, Matsuo Y, Yahiro E, Uehara Y, Saku K.A novel inducible cholesterol efflux peptide, FAMP, protects against myocardial ischemia reperfusion injury through a nitric oxide pathway. International Journal of Cardiology.2016.202:810-816
Norimatsu K, Miura S, Suematsu Y, Shiga Y, Miyase Y, Nakamura A, Zhang B, Saku K.Association between pentraxin 3 levels and aortic valve calcification.J Cardiol.2016.68:76-82
Miyase Y, Miura S, Shiga Y, Yano M, Suematsu Y, Adachi S, Norimatsu K, Nakamura A, Saku K.Association between the severity of coronary artery stenosis and the combination of the difference in blood pressure between arms and brachial-ankle pulse wave velocity.Clin Exp Hypertens. 2016. 38:81-88
Imaizumi S, Miura S, Takata K, Takamiya Y, Kuwano T, Sugihara M, Ike A, Iwata A, Nishikawa H, Saku K.Association between cholesterol efflux capacity and coronary restenosis after successful stent implantation.Heart Vessels.2016.31:1257-1265
Motozato K, Miura S, Shiga Y, Kusumoto T, Adachi S, Inoue T, Fujisawa K, Saku K.Efficacy and safety of two single-pill fixed-dose combinations of angiotensin II receptor blockers/calcium channel blockers in hypertensive patients (EXAMINER study).Clin Exp Hypertens. 2016. 38(1):45-50
Suematsu Y, Miura S, Zhang B, Uehara Y, Ogawa M, Yonemoto N, Nonogi H, Nagao K, Kimura T, Saku K.Association between dental caries and out-of-hospital cardiac arrests of cardiac origin in Japan.J Cardiol.2016.67:384-391
Yamamoto T, Miura S, Suematsu Y, Kuwano T, Sugihara M, Ike A, Iwata A, Nishikawa H, Saku K.A relative difference in systolic blood pressure between arms by synchronal measurement and conventional cardiovascular risk factors are associated with the severity of coronary atherosclerosis.Heart Vessels. 2016. 31:863-870
Hitaka Y*, Ogawa M*, Zhang B, Goto S, Nagata Y, Morii J, Imaizumi S, Yasuda T, Matsumoto N, Matsunaga A, Saku K.Circadian variations in laboratory measurements of coagulation assays after administration of rivaroxaban or warfarin in patients with nonvalvular atrial fibrillation.Journal of Cardiology. 2016. 68(6):529-535
Ikenaga M, Higaki Y, Saku K, Uehara Y.High-Density Lipoprotein Mimetics: a Therapeutic Tool for Atherosclerotic Diseases.J Atheroscler Thromb.2016.23(4):385-94
Suematsu Y, Miura S, Goto M, Matsuo Y, Arimura T, Kuwano T, Imaizumi S, Iwata A, Yahiro E, Saku K.LCZ696, an angiotensin receptor-neprilysin inhibitor, improves cardiac function with the attenuation of fibrosis in heart failure with reduced ejection fraction in streptozotocin-induced diabetic mice.European Journal of Heart Failure. 2016.01.07. 18(4):386-393
Ng VG, Mori K, Costa RA, Kish M, Mehran R, Urata H, Saku K, Stone GW, Lansky AJ.Impact of gender on infarct size, ST-segment resolution, myocardial blush and clinical outcomes after primary stenting for acute myocardial infarction: Substudy from the EMERALD trial.Int J Cardiol. 2016.03.15. 207:269-276
Nagao K, Nonogi H, Yonemoto N, Gaieski DF, Ito N, Takayama M, Shirai S, Furuya S, Tani S, Kimura T, Saku K; Japanese Circulation Society With Resuscitation Science Study (JCS-ReSS) Group*. Duration of Prehospital Resuscitation Efforts After Out-of-Hospital Cardiac Arrest. Circulation. 2016.04.05. 133(14):1386-1396
Hitaka Y, Miura S, Koyoshi R, Suematsu Y, Miyase Y, Norimatsu K, Adachi S, Shiga Y, Morito N, Nishikawa H, Saku K.Associations between parameters of flow-mediated vasodilatation obtained by continuous measurement approaches and the presence of coronary artery disease and the severity of coronary atherosclerosis.Clin Exp Hypertens. 2016.06.30. 38(5):443-450
Yano M, Miura S, Shiga Y, Miyase Y, Suematsu Y, Norimatsu K, Nakamura A, Adachi S, Nishikawa H, Saku K.Association between smoking habits and severity of coronary stenosis as assessed by coronary computed tomography angiography.Heart Vessels. 2016.07. 31(7):1061-1068
Ueda T, Miura S, Suematsu Y, Shiga Y, Kuwano T, Sugihara M, Ike A, Iwata A, Nishikawa H, Fujimi K, Saku K.Association of Arterial Pressure Volume Index With the Presence of Significantly Stenosed Coronary Vessels.J Clin Med Res.2016.08. 8(8):598-604
Adachi S, Miura S, Shiga Y, Arimura T, Kuwano T, Kitajima K, Ike A, Sugihara M, Iwata A, Nishikawa H, Morito N, Saku K.Depressor and Anti-Inflammatory Effects of Angiotensin II Receptor Blockers in Metabolic and/or Hypertensive Patients With Coronary Artery Disease: A Randomized, Prospective Study (DIAMOND Study).J Clin Med Res. 2016.08.30. 8(10):743-748
Ueda T, Miura S, Fujimi K, Ishida T, Matsuda T, Fujita M, Ura Y, Kaino K, Sakamoto M, Horita T, Arimura T, Shiga Y, Kuwano T, Kitajima K, Saku K.Assessment of various parameters using simple non-invasive tests in patients with cardiovascular diseases with or without cardiac rehabilitation. IJC Heart & Vasculature. 2016.09. 12:63-67
Idemoto Y, Miura S, Norimatsu K, Suematsu Y, Hitaka Y, Shiga Y, Morii J, Imaizumi S, Kuwano T, Iwata A, Zhang B, Ogawa M, Saku K.Evaluation of the antithrombotic abilities of non-vitamin K antagonist oral anticoagulants using the Total Thrombus-formation Analysis System℗ . Heart Vessels. 2016.1.21. 32:309-316
Goto M, Miura S, Suematsu Y, Idemoto Y, Takata K, Imaizumi S, Uehara Y, Saku K.Rivaroxaban, a factor Xa inhibitor, induces the secondary prevention of cardiovascular events after myocardial ischemia reperfusion injury in mice.Int J Cardiol. 2016.10.01. 220:602-607
Kuwano T, Miura S, Norimatsu K, Arimura T, Shiga Y, Tomita S, Nakayama A, Matsuo Y, Imaizumi S, Saku. KAdvanced glycation of high-density lipoprotein and the functionality of aldosterone release in type 2 diabetes.Hypertens Res.2016.10.13.40(3):271-276
Miura S, Suematsu Y, Matsuo Y, Tomita S, Nakayama A, Goto M, Arimura T, Kuwano T, Yahiro E, Saku K.The angiotensin II type 1 receptor-neprilysin inhibitor LCZ696 blocked aldosterone synthesis in a human adrenocortical cell line. Hypertens Res. 2016.11. 39(11):758-763
Sai K, Kajinami K, Akao H, Iwadare M, Sato-Ishida R, Kawai Y, Takeda K, Tanimoto T, Yamano T, Akasaka T, Ishida T, Hirata K, Saku K, Yagi S, Soeki T, Sata M, Ueno M, Miyazaki S, Shiraki A, Oyama J, Node K, Sugamura K, Ogawa H, Kurose K, Maekawa K, Matsuzawa Y, Imatoh T, Hasegawa R; Japanese Pharmacogenomics Data Science Consortium, Saito Y. A possible role for HLA-DRB1*04:06 in statin-related myopathy in Japanese patients.Drug Metabolism And Pharmacokinetics. 2016.12. 31:467-470
Motozato K, Miura S, Shiga Y, Kusumoto T, Saku K.Efficacy and Safety of a Single-Pill Fixed-Dose Combination of Azilsartan and Amlodipine.J Clin Med Res.2016.12.8(12):888-892
Sugihara H*, Idemoto Y, Kuwano T*, Nagata Y, Morii J, Sugihara M, Ogawa M, Miura S, Saku K.Evaluation of the Antithrombotic Effects of Rivaroxaban and Apixaban Using the Total Thrombus-Formation Analysis System®: In Vitro and Ex Vivo Studies. J Clin Med Res. 2016.12. ;8(12):899-907
Ikeda T, Atarashi H, Inoue H, Uchiyama S, Kitazono T, Yamashita T, Shimizu W, Kamouchi M, Kaikita K, Fukuda K, Origasa H, Sakuma I, Saku K, Okumura Y, Nakamura Y, Morimoto H, Matsumoto N, Tsuchida A, Ako J, Sugishita N, Shimizu S, Shimokawa H.Study Design and Baseline Characteristics of the EXPAND Study: Evaluation of Effectiveness and Safety of Xa Inhibitor, Rivaroxaban for the Prevention of Stroke and Systemic Embolism in a Nationwide Cohort of Japanese Patients Diagnosed as Non-Valvular Atrial Fibrillation. The Tohoku Journal of Experimental Medicine. 2016.12. 240(4):259-268
Hasegawa K, Kawachi E, Uehara Y, YoshidaT, Imaizumi S, Ogawa M, Miura S, Saku K.Improved 68Ga‐labeling method using ethanol addition: Application to the α‐helical peptide DOTA‐FAMP. Journal of Labelled Compounds and Radiopharmaceuticals. 2016.12.07. 60(1):55-61
Ishida T, Miura S, Fujimi K, Ueda T, Ueda Y, Matsuda T, Sakamoto M, Arimura T, Shiga Y, Kitajima K, Saku K.Visit-to-Visit Variability and Reduction in Blood Pressure After a 3-Month Cardiac Rehabilitation Program in Patients With Cardiovascular Disease.Int Heart J. 2016.9.28. 57(5):607-614
2015年
Shimizu T, Tanigawa H, Miura S, Kuwano T, Takata K, Suematsu Y, Imaizumi S, Yahiro E, Zhang B, Uehara Y, Saku K.Newly developed apolipoprotein A-I mimetic peptide promotes macrophage reverse cholesterol transport in vivo. International Journal of Cardiology.2015.1;192:82-8.
Yahiro E, Miura S, Suematsu Y, Matsuo Y, Arimura T, Kuwano T, Imaizumi S, Iwata A, Uehara Y, Saku K.Addition of a Nitric Oxide Donor to an Angiotensin II Type 1 Receptor Blocker May Cancel Its Blood Pressure-Lowering Effects. International Heart Journal.2015.56(6):656-660
Suematsu Y, Miura S, Takata K, Shimizu T, Kuwano T, Imaizumi S, Matsuo Y, Yahiro E, Uehara Y, Saku K.A novel inducible cholesterol efflux peptide, FAMP, protects against myocardial ischemia reperfusion injury through a nitric oxide pathwayInternational Journal of Cardiology.2015.202(2016):810816
Kumagai N, Ogawa M, Koyoshi R, Morii J, Yasuda T, Matsumoto N,Matsuo K, Zhang B, Saku K.Autonomic Imbalance and QT Dynamics in Idiopathic Ventricular Fibrillation 福岡大学医学紀要.2015.42(2):235-240
Okamura K, Urata H.Prevalence and Characteristic of Treatment-Resistant Hypertension among Hypertensive Japanese OutpatientsInternational Journal of Clinical Medicine.2015.623-634
Okamura K, Okuda T, Kumagai N, Mitsutake R, Urata H.Antihypertensive Effect and Safety of a Candesartan/Hydrochlorothiazide Combination in Patients with Uncontrolled HypertencionTherapeutic Research.2015.36(5):439-448
Nagata I, Ike A, Nishikawa H, Zhang B, Sugihara M, Mori K, Iwata A, Kawamura A, Shirai K, Uehara Y, Ogawa M, Miura S, Saku K. Associations between lipid profiles and MACE in hemodialysis patients with percutaneous coronary intervention: From the FU-Registry. Journal of Cardiology.2015.65:115-111
Norimatsu K, Miura S, Suematsu Y, Shigawa Y, Miyase Y, Nakamura A, Yamada M, MatsunagaA, Saku K. Associations between glycated albmin or hemoglobin A1c and the presence of coronary artery desease. Journal of Cardiology.2015.65(6):487-493
Ike A, Shirai K, Nishikawa H, Iwata A, Yahiro E, Sugihara M, Kawamura A, Uehara Y, Zhang B, Ogawa M, Mori K, Miura S, Saku K. Associations between different types of hypoglycemic agents and the clinical outcome of percutaneous coronary intervention in diabetic patients-From the FU-Registry. Journal of Cardiology.2015.65(5):390-396
Hitaka Y, Miura S, Koyoshi R, Shiga Y, Miyase Y, Norimatsu K, Nakamura A, Adachi S, Kuwano T, Sugihara M, Ike A, Nishikawa H, Saku K.Impact of the Absolute Difference in Diastolic Blood Pressure Between Arms in Patients With Coronary Artery Disease. J Clin Med Res20157(11):873-879
Devarajan S, Yahiro E, Uehara Y, Habe S, Nishiyama A, Miura S, Saku K, Urata H.Depressor Effect of Chymase Inhibitor in Mice with High Salt-Induced Moderate Hypertension. Am J Physiol Heart Circ Physiol.2015309(11):H1987-96
Norimatsu K, Miura S, Suematsu Y, Shiga Y, Miyase Y, Nakamura A, Zhang B, Saku K.Association between pentraxin 3 levels and aortic valve calcification. Journal of Cardiology. 2015, 68:76-82
Miyase Y, Miura S, Shiga Y, Yano M, Suematsu Y, Adachi S, Norimatsu K, Nakamura A, Saku K.Association between the severity of coronary artery stenosis and the combination of the difference in blood pressure between arms and brachial-ankle pulse wave velocity.Clin Exp Hypertens. 2015.Epub ahead of print
Shiga Y, Miura S, Adachi S, Suematsu Y, Sugihara M, Iwata A, Yahiro E, Nishikawa H, Ogawa M, Saku K.Visit-to-Visit Variability and Seasonal Variation in Blood Pressure With Single-Pill Fixed-Dose Combinations of Angiotensin II Receptor Blocker/Calcium Channel Blocker and Angiotensin II Receptor Blocker/Diuretic in Hypertensive Patients. J Clin Med Res.2015.(10):802-6
Imaizumi S, Miura S, Takata K, Takamiya Y, Kuwano T, Sugihara M, Ike A, Iwata A, Nishikawa H, Saku K.Association between cholesterol efflux capacity and coronary restenosis after successful stent implantation. Heart Vessels. 2015, 31:1257-1265
Suematsu Y, Miura S, Zhang B, Uehara Y, Ogawa M, Yonemoto N, Nonogi H, Nagao K, Kimura T, Saku K.Association between dental caries and out-of-hospital cardiac arrests of cardiac origin in Japan. Journal of Cardiology. 2015, 67:384-391
Gondo K, Miura S, Suematsu Y, Shiga Y, Kuwano T, Sugihara M, Ike A, Iwata A, Motozato K, Kusumoto T, Nishikawa H, Saku K.Association Between Visit-to-Visit Variability in Blood Pressure and Cardiovascular Events in Hypertensive Patients After Successful Percutaneous Coronary Intervention. J Clin Med Res.2015.7(7):545-50
Yamamoto T, Miura S, Suematsu Y, Kuwano T, Sugihara M, Ike A, Iwata A, Nishikawa H, Saku K.A relative difference in systolic blood pressure between arms by synchronal measurement and conventional cardiovascular risk factors are associated with the severity of coronary atherosclerosis. Heart Vessels. 2015, 31:863-870
Miura S, Nakayama A, Tomita S, Matsuo Y, Suematsu Y, Saku K.Comparison of aldosterone synthesis in adrenal cells, effect of various AT1 receptor blockers with or without atrial natriuretic peptide. Clinical and Experimental Hypertension.2015.37(5):353-357
Morito N, Miura S, Yano M, Hitaka Y, Nishikawa H, Saku K.Association between a ban on smoking in a hospital and the in-hospital onset of acute myocardial infarction. Cardiol Res.2015.6(3):278-282.
Yahiro E, Kawachi E, Miura S, Kuwano T, Imaizumi S, Iwata A, Hasegawa K, Yano T, Watanabe Y, Uehara Y, Saku K. Comparison of 64Cu and 68Ga for Molecular Imaging of Atherosclerosis using the Apolipoprotein A-I Mimetic Peptide FAMP.J Cardiovasc Dis Diag.2015.3:201. doi:10.4172/2329-9517.1000201
Fujimi K, Miura S, Matsuda T, Fujita M, Ura Y, Kaino K, Sakamoto M, Hirota T, Arimura T, Shiga Y, Saku K. Influence of a cardiac rehabilitation program on renal function in patients with cardiovascular disease in a 1-year follow-up. Cardiol Res.2015.6(4-5):311-315
Tokunaga M*, Suematsu Y*, Miura S, Kuwano T, Iwata A, Nishikawa H, Zhang B, Yonemoto N, Nonogi H, Nagao K, Kimura T, Saku K.(*co-first authors)On behalf of the Japanese Circulation Society Resuscitation Science Study (JCS-ReSS) Group. Association between the consumption of carbonated beverages and out-of-hospital cardiac arrests of cardiac origin in Japan. World J Cardiovasc Dis.2015.5:361-372
Takata K, Imaizumi S, Zhang B, Miura S, Saku K.Stabilization of high-risk plaques.Cardiovasc Diagn Ther.2015.doi: 10.3978/j.issn.2223-3652
Yasunaga T, Yasuno T, Imaizumi S, Nakashima H.The Use of Multiplex Ligation Dependent Probe Amplification Technology for Genetic Analysis of the Entire PKD1 Gene and PKD2 Gene. J Clin Med Case Reports.2015.2(1):3
Nagata I, Ike A, Nishikawa H, Sugihara M, Mori K, Iwata A, Kawamura A, Shirai K, Zhang B, Miura S, Saku K. Significant differences in lipid profile associated with MACEs between hemodialysis and non-HD patients from FU-Registry. J Cardiol. 2015;65:105-111.
Gondo K, Miura S, Suematsu Y, Shiga Y, Kuwano T, Sugihara M, Ike A, Iwata A, Motozato T, Kusumoto T, Nishikawa H, Saku K. Association between visit-to-visit variability in blood pressure and cardiovascular events in hypertensive patients after successful percutaneous coronary intervention. J Clin Med Res. 2015;7:545-550.
Shimizu T*, Tanigawa H*, Miura S, Kuwano T, Takata K, Suematsu Y, Imaizumi S, Yahiro E, Zhang B, Uehara Y, Saku K. Newly developed apolipoprotein A-I mimetic peptide promotes macrophage reverse cholesterol transport in vivo. Int J Cardiol. 2015;192:82-88. (*co-first authors)
Ike A, Shirai K, Yahiro A, Sugihara M, Kawamura A, Iwata A, Uehara Y, Zhnag B, Ogawa M, Mori K, Mura S, Saku K. Association between the use of new and old hypoglycemic agents and the clinical outcome of percutaneous coronary intervention in diabetic patients: - From the FU-Registry -. J Cardiol. 2015;65:390-396.
Norimatsu K, Miura S, Suematsu Y, Shiga Y, Miyase Y, Nakamura A, Yamada M, Matsunaga A, Saku K. Associations between glycated albumin or hemoglobinA1c and the presence of coronary artery disease. J Cardiol. 2015;65:487-493.
Yahiro E, Kawachi E, Miura S, Kuwano T, Imaizumi S, Iwata A, Hasegawa K, Yano T, Watanabe Y, Uehara Y, Saku K. Comparison of 64Cu and 68Ga for Molecular Imaging of Atherosclerosis using the Apolipoprotein A-I Mimetic Peptide FAMP. J Cardiovasc Dis Diag. 2015;3:201. doi:10.4172/2329-9517.1000201.
Morito N, Miura S, Yano M, Hitaka Y, Nishikawa H, Saku K. Association between a ban on smoking in a hospital and the in-hospital onset of acute myocardial infarction. Cardiol Res. 2015;6:278-282.
Shiga Y, Miura S, Norimatsu K, Hitaka Y, Nagata I, Morii J, Kuwano T, Uehara Y, Inoue A, Shirotani T, Fujisawa K, Matsunaga E, Saku K. Efficacy and safety of combination therapy of high-dose losartan and hydrochlorothiazide in patients with hypertension. J Renin Angiotensin Aldosterone Syst. 2015. in press.
Miura S, Nakayama A, Tomita S, Matsuo Y, Suematsu Y, Saku K. Comparison of aldosterone synthesis in adrenal cells, effect of various AT1 receptor blockers with or without atrial natriuretic peptide. Clin Exp Hypertens. 2015. in press.
Yamamoto T, Miura S, Suematsu Y, Kuwano T, Sugihara M, Ike A, Iwata A, Nishikawa H, Saku K. A relative difference in systolic blood pressure between arms by synchronal measurement and conventional cardiovascular risk factors are associated with the severity of coronary atherosclerosis. Heart Vessels. 2015. in press.
Miyase Y, Miura S, Shiga Y, Yano M, Suematsu Y, Adachi S, Norimatsu K, Nakamura A, Saku K.Association between the severity of coronary artery stenosis and the combination of the difference in blood pressure between arms and brachial-ankle pulse wave velocity. Clin Exp Hypertens. 2015, 38:81-88
Motozato K, Miura S, Shiga Y, Kusumoto T, Adachi S, Inoue T, Fujisawa K, Saku K. Efficacy and safety of two single-pill fixed-dose combinations of angiotensin II receptor blockers/calcium channel blockers in hypertensive patients (EXAMINER study). Clin Exp Hypertens. 2015. in press.
Yohiro E, Miura S, Suematsu Y, Matsuo Y, Arimura T, Kuwano T, Imaizumi S, Iwata A, Uehara Y, Saku K. Addition of a nitric oxide donor to an angiotensin II type 1 receptor blocker may cancel its blood pressure-lowering effects. Int Heart J. 2015. in press.
Suematsu Y, Miura S, Zhang B, Uehara Y, Ogawa M, Yonemoto N, Nonogi H, Nagao K, Kimura T, Saku K, on behalf of the Japanese Circulation Society Resuscitation Science Study (JCS-ReSS) Group. Association between dental caries and out-of-hospital cardiac arrests of cardiac origin in Japan. J Cardiol. 2015. in press.
Yano M, Miura S, Shiga Y, Miyase Y, Suematsu Y, Norimatsu K, Nakamura A, Adachi S, Nishikawa H, Saku K. Association between smoking habits and severity of coronary stenosis as assessed by coronary computed tomography angiography. Heart & Vessels. 2015. in press.
Shiga Y, Miura S, Adachi S, Suematsu Y, Sugihara M, Iwata A, Yahiro E, Nishikawa H, Ogawa M, Saku K. Visit-to-visit variability and seasonal variation in blood pressure with single-pill fixed-dose combinations of angiotensin II receptor blocker/calcium channel blocker and angiotensin II receptor blocker/diuretic in hypertensive patients. J Clin Med Res. 2015. in press.
2014年
Miura SI, Matsuo Y, Nakayama A, Tomita S, Suematsu Y, Saku K. Ability of the new AT1 receptor blocker azilsartan to block angiotensin II-induced AT1 receptor activation after wash-out. J Renin Angiotensin Aldosterone Syst 15(1):7-12, 2014
Serikawa T, Miura S, Okabe M, Hongo H, Tokutome M, Yoshikawa T, Takesue K, Adachi S, Osaka K, Matsukawa R, Yanagi D, Nozoe M, Kozai T, Hironaga K, Saku K, Yamamoto Y. The ratio of eicosapentaenoic acid to arachidonic acid is a critical risk factor for acute coronary syndrome in middle-aged older patients as well as younger adult patients. Journal of Cardiology 63(1):35-40, 2014
Suematsu Y, Miura S, Zhang B, Uehara Y, Tokunaga M, Yonemoto N, Nonogi H, Nagao K, Kimura T, Saku K. Associations between the consumption of different kinds of seafood and out-of-hospital cardiac arrests of cardiac origin in Japan. IJC Heart & Vessels 2:8-14, 2014
Nakamura A, Miura SI, Sugihara M, Miyase Y, Norimatsu K, Shiga Y, Nishikawa H, Saku K. Contrast between innovator drug- and generic drug-induced renal dysfunction on coronary angiography (CONTRAST study). Heart Vessels 29(5):603-610, 2014
Nagata I, Shiga Y, Miura S, Norimatsu K, Hitaka Y, Morii E, Kuwano T, Inoue A, Fujisawa K, Shirotani T, Matsunaga E, Uehara Y, Saku K. Comparison of the efficacy and safety of single-pill fixed-dose combinations of olmesartan/azelnidipine and valsartan/amlodipine in patients with hypertension (RENOVATE Study). Exp Clin Cardiol 20(1):1920-1938, 2014
Miyase Y, Miura S, Shiga Y, Nakamura A, Norimatsu K, Nishikawa H, Saku K. The ratio of low-frequency to high-frequency in ambulatory electrocardiographic monitoring immediately before coronary angiography as a predictor of the presence of coronary artery disease. J Clin Med Res 6(1):36-43, 2014
Sakai T, Sato B, Hara K, Hara Y, Naritomi Y, Koyanagi S, Hara H, Nagao T, Ishibashi T. Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function. Vasc Health Risk Manag 17;10:591-7, 2014
Ishibashi T, Sato B, Shibata S, Sakai T, Hara Y, Naritomi Y, Koyanagi S, Hara H, Nagao T. Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: a randomized, double-blind, placebo-controlled pilot study. Int Immunopharmacol 21(2):468-73, 2014
Yamaguchi S, Zhang B, Tomonaga T, Seino U, Kanagawa A, Segawa M, Nagasaka H, Suzuki A, Miida T, Yamada S, Sasaguri Y, Doi T, Saku K, Okazaki M, Tochino Y, Hirano K. Selective evaluation of high density lipoprotein from mouse small intestine by an in situ perfusion technique. J Lipid Res 55(5):905-18, 2014
Shiga Y, Miura S, Nishikawa H, Sugihara H, Nakashima Y, Takamatsu Y, Koga K, Koga S, Katayama Y, Yoshida T, Iwasaki H, Saku K. Very rare case of large obstructive myxofibrosarcoma of the right ventricle assessed with multi-diagnostic imaging techniques. Intern Med 53(7):739-42, 2014
Nakamura A, Miura SI, Sugihara M, Miyase Y, Norimatsu K, Shiga Y, Nishikawa H, Saku K. Is pentraxin 3 a biomarker, a player, or both in the context of coronary atherosclerosis and metabolic factors? Heart Vessels Epub ahead of print, 2014
Shimizu T, Miura S, Tanigawa H, Kuwano T, Zhang B, Uehar Y, Saku K. Rosvastatin activates ATP-binding cassette transporter A-1 dependent efflux ex vivo and promotes reverse cholesterol transport in macrophage cells in mice fed a high-fat diet. Arterioscler Thromb Vasc Biol 34(10):2246-2253, 2014
Shiga Y, Miura SI, Norimatsu K, Hitaka Y, Nagata I, Koyoshi R, Morii J, Kuwano T, Uehara Y, Inouye A, Shirotani T, Fujisawa K, Matsunaga E, Saku K. Efficacy and Safety of combination therapy of high-dose losartan and hydrochlorothiazide in patients with hypertension. J Renin Angiotensin Aldosterone Syst Epub ahead of print, 2014
Takata K, Imaizumi S, Kawachi E, Suematsu Y, Shimizu T, Abe S, Matsuo Y, Tsukahara H, NodaK, Yahiro E, Zhang B, Uehara Y, Miura S, Saku K. Impact of cigarette smoking cessation on high-density lipoprotein functionality. Circulation Journal 25;78(12):2955-62, 2014
Fujimi K, Miura S, Fujita M, Ura Y, Kaino K, Horita T, Matsuda T, Hirota Y, Ogawa M, Saku K. Effects of Cardiac Rehabilitation in Patients with Cardiac Resynchronization Therapy. Exp Clin Cardiol 20:3565-3568, 2014
Norimatsu K, Miura S, Suematsu Y, Shiga Y, Yano M, Hitaka Y, Kuwano T, Morii J, Yasuda T, Ogawa M, Saku K. Assessment of the circadian variation in the anticoagulant effect of rivaroxaban using a novel automated microchip flow-chamber system for the quantitative evaluation of thrombus formation. IJC Heart & Vessels 218-220, 2014
Miura S, Suematsu Y, Matsuo Y, Imaizumi S, Yahiro E, Uehara Y, Saku K. Induction of endothelial tube formation and anti-inflammation by newly developed apolipoprotein A-I mimetic peptide. IJC Metabolic & Endocrine 70-72, 2014
Yahiro E, Uehara Y, Kawachi E, Ando S, Miura S, Saku K. Improved survival rate after myocardial infarction using an inducible cholesterol efflux peptide: FAMP. Heart Vessels 135-137, 2014
Nagata Y, Miura S, Suematsu Y, Sugihara M, Ike A, Iwata A, Nishikawa H, Kawamura A, Saku K. Association between major adverse cardiovascular events and brachial-ankle pulse wave velocity and a difference in blood pressure between arms after percutaneous coronary intervention. Exp Clin Cardiol 4838-4848, 2014
Yamamoto T, Miura S, Shiga Y, Miyase Y, Nakamura A, Ike A, Sugihara M, Iwata A, Nishikawa H, Saku K. Association between mild myocardial injury post percutaneous coronary intervention and improvement of cardiac function through an increase in tissue inhibitor of metalloproteinase-1. Exp Clin Cardiol 4849-4855, 2014
Fujimi K, Miura S, Sugihara M, Fujita M, Ura Y, Kaino K, Horita T, Matsuda T, Ike A, Nishikawa H, Saku K. Impact of a cardiac rehabilitation program on cardiac function after acute myocardial infarction. Exp Clin Cardiol 20:3561-3564, 2014
Yamamoto T, Miura S, Shiga Y, Nagata Y, Miyase Y, Suematsu Y, Uehara Y, Saku K. A relative difference in blood pressure between arms by synchronal measurement is associated with hypertension. Exp Clin Cardiol 6574-6578, 2014
Kawamura A, Miura S, Matsuo Y, Tanigawa H, Saku K. Azelnidipine-, but not amlodipine-, induced secretion of vascular endothelial growth factor from smooth muscle cells promotes endothelial tube formation. Cardiol Res 145-150, 2014
Bhimani AA, Yasuda T, Sadrpour SA, Khrestian CM, Lee S, Zeng D, Belardinelli L, Waldo AL. Ranolazine terminates atrial flutter and fibrillation in a canine model. Heart Rhythm 11(9):1592-1599, 2014
Yang Y,Kuwano T,Lagor WR,Albert CJ,Brenton S,Rader DJ,Ford DA,Brown RJ. Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species. Lipids 49(6):505-515, 2014
2013年
Saku K, Iwata A. (JCS Joint Working Group) Guidelines for Secondary Prevention of Myocardial Infarction (JCS 2011). -Digest Version- JCS Joint Working Group Circulation Journal 77(1): 231-248, 2013
Miura S, Okabe A, Matsuo Y, Karnik SS, Saku K. Unique binding behavior of the recently approved angiotensin Ⅱreceptor blocker azilsartan compared with that of candesartan. Hypertension Research 36:134-139, 2013
Sugihara M, Miura S, Nishikawa H,Ike A, Mori K, Iwata A, Kawamura A, Saku K. Characteristics of patients and types of lesions in patients with drug-eluting or bare-metal stent implantation in small coronary arteries From the FU-Registry. Journal of Cardiology 61:117-121, 2013
The Anti-Smoking Promotion Committee of the Japanese Circulation Society. Saku K, Iida M, Uehara Y, Ebina T, Murohara T, Takihara K, Higaki J, Takahashi Y, Fujiwara H. Anti-Smoking Declaration 2013 -A Message From the Japanese Circulation Society-. Circulation Journal 77(3): 559-560, 2013
Uehara Y, Ando S, Yahiro E, Oniki K, Ayaori M, Abe S, Kawachi E, Zhang B, Shioi S, Tanigawa H, Imaizumi S, Miura S, Saku K. FAMP, a Novel ApoA-I Mimetic Peptide, Suppresses Aortic Plaque Formation Through Promotion of Biological HDL Function in ApoE-Deficient Mice. J Am Heart Assoc. May 24;2(3), 2013
Kawachi E, Uehara Y, Hasegawa K, Yahiro E, Ando S, Wada Y, Yano T, Nishikawa H, Shiomi M, Miura S, Watanabe Y, Saku K. Novel molecular imaging of atherosclerosis with gallium-68-labeled apolipoprotein A-I mimetic peptide and positron emission tomography. Circ J. 77(6):1482-9, 2013
JCS Joint Working Group. Saku K. (Independent Assessment Committee) Guidelines for Treatment of Acute Heart Failure (JCS 2011) -Digest Version-. Circulation Journal 77(8): 2157-2201, 2013
Suematsu Y, Murasato Y, Miura S, Horiuchi M, Yamamoto T, Takata K, Saku K. Safety and feasibility of high-dose administration of nicorandil before reperfusion therapy in acute myocardial infarction. Cardiovascular Intervention Therapeutics. 28(4):352-61, 2013
Tanaka T, Miura S, Tanaka M, Uehara Y, Hirano T, Saku K. Efficacies of Controlling Morning Blood Pressure and Protecting the Kidneys by Treatment With Valsartan and Nifedipine CR or Valsartan and Amlodipine (MONICA Study). J Clin Med Res 5(6):432-40, 2013
Uehara Y, Fujimi K, Yahiro E, Abe S, Devarajan S, Saku K, Urata H. Induction of tissue angiotensin Ⅱ-forming activity in two-kidney, one-clip hypertensive hamster model. World Journal of Hypertension 3(2):9-17, 2013
Kumagai N, Miura S, Zhang B, Noda K, Saku K, Zenith Trial Investigators. Effects of ezetimibe on hypercholesterolemia in the lipid profile patients with metabolic syndrome : Zenith Trial. IJC Metabolic & Endocrine 7月12日, 2013
Morii J, Miura S, Ike A, Shiga Y, Sugihara M, Iwata A, Kawamura A, Nishikawa H, Saku K. Comparison of the efficacies of irbesartan and olmesartan after successful coronary stent implantation. Intern Med. 52(7):713-9, 2013
Miura S, Nakao N, Hanzawa H, Matsuo Y, Saku K, Karnik SS. Reassessment of the unique mode of binding between angiotensin II type 1 receptor and their blockers. PLoS One. 8;8(11):e79914., 2013
Nakamura A, Miura SI, Sugihara M, Miyase Y, Norimatsu K, Shiga Y, Nishikawa H, Saku K. Contrast between innovator drug- and generic drug-induced renal dysfunction on coronary angiography (CONTRAST study). Heart Vessels Epub ahead of print, 2013
2012年
Shiga Y, Miura SI, Mitsutake R, Uehara Y, Inoue A, Saku K. Effect of fixed-dose losartan/hydrochorothiazide on brain natriuretic peptide in patients with hypertension. J Renin Angiotensin Aldosterone Syst. 13(1):107-112, 2012
Kiya Y, Miura S, Matsuo Y, Karnik SS, Saku K. Abilities of candesartan and other AT1 receptor blockers to impair angiotensin Ⅱ-induced AT1 receptor activation after washout. J Renin Angiotensin Aldosterone Syst. 13(1):76-83, 2012
Nakamura A, Uehara Y, Kawamura A, Saku K. Giant Thrombus Filling the Pulmonary Trunk. INTERNAL MEDICINE 51(1):333, 2012
Saku K. Guidelines for Smorking Cessation (JCS2010) -Digest Version- JCS Joint Working Group Circulation Journal 76(4):1024-1043, 2012
Chen PS, Ogawa M, Maruyama M, Chua SK, Chang PC, Rubart-von der Lohe M, Chen Z, Ai T, Lin SF. Imaging Arrhythmogenic Calcium Signaling in Intact Hearts. Pediatr Cardiol 33(6):968-974, 2012
Noda K, Zhang B. Iwata A, Nishikawa H, Ogawa M, Nomiyama T, Miura S, Sako H, Matsuo K, Yahiro E, Yanase T, Saku K, on behalf of the STYLIST Study Investigators. Lifestyle changes through the use of delivered meals and dietary counseling in a single-blind study. The STYLIST study. Circulation Journal 76(6):1335-1344, 2012
Koyoshi R, Miura S, Kumagai N, Shiga Y, Mitsutake R, Saku K. Clinical Significance of Flow-Mediated Dilation, Brachial Intima-Media Thickness and Pulse Wave Velocity in Patients With and Without Coronary Artery Disease. Circulation Journal 76(6):1469-1475, 2012
Fukuda Y, Sumi-Inoue Y, Matsumoto K, Kubota K, Sumi S, Tojo H, Yamanouchi Y, Miura S, Saku K, Urata H. Pleiotropic Effects of High-dose losartan on Uricosuria and Increased High Molecular Weight Adioponectin in Hypertensive Patients Therapeutic Research 33(2):221-228, 2012
Fukushima M, Miura S, Mitsutake R, Fukushima T, Fukushhima K, Saku K. Cholesterol Metabolism in Patients With Hemodialysis in the Presence or Absence Coronary Artery Disease. Circulation Journal 76(8):1980-1986, 2012
Zhang B, Kawachi E, Matsunaga A, Imaizumi S, Noda K, Uehara Y, Miura S, Yoshinaga K, Kuroki M, Saku K. Reactivity of direct assays for low-density lipoprotein (LDL) cholesterol toward charge-modified LDL in hypercholesterolemia. Circulation Journal 76(9):2241-2248, 2012
Arimura T, Miura S, Ike A, Sugihara M, Iwata A, Nishikawa H, Kawamura A, Saku K. Comparison of the efficacy and safety of statin and statin/ezetimibe therapy after coronary stent implantation in patients with stable angina. Journal of Cardiology 60:111-118, 2012
Shiga Y, Miura S, Hitaka Y, Saku K. Right aortic arch with Kommerell's diverticulum using 64-MDCT. Intern Med. 51(11):1437-1438, 2012
Shiga Y, Miura S, Mitsutake R, Norimatsu K, Nagata I, Arimura T, Shimizu T, Morii J, Kuwano T, Uehara Y, Inoue A, Shirotani T, Fujisawa K, Matsunaga E, Saku K. Efficacy and safety of a single-pill fixed-dose combination of high-dose telmisartan/hydrochlorothiazide in patients with uncontrolled hypertension. J Renin Angiotensin Aldosterone Syst. 13(3):394-400, 2012
Devarajan A, Grijalva VR, Bourquard N, Meriwether D 3rd, Imaizumi S, Shin BC, Devaskar SU, Reddy ST. Macrophage paraoxonase 2 regulates calcium homeostasis and cell survival under endoplasmic reticulum stress conditions and is sufficient to prevent the development of aggravated atherosclerosis in paraoxonase 2 deficiency/apoE(-/-) mice on a Western diet. Mol Genet Metab 107(3):416-27, 2012
Su F, Grijalva V, Navab K, Ganapathy E, Meriwether D, Imaizumi S, Navab M, Fogelman AM, Reddy ST, Farias-Eisner R. HDL mimetics inhibit tumor development in both induced and spontaneous mouse models of colon cancer. Mol Cancer Ther. 11(6):1311-1319, 2012
Miura S, Kiya Y, Hanzawa H, Nakao N, Fujino M, Imaizumi S, Matsuo Y, Yanagisawa H, Koike H, Komuro I, Karnik SS, Saku K. Small molecules with similar structures exhibit agonist, neutral antagonist or inverse agonist activity toward angiotensin II type 1 receptor. PLoS One 7(6):e37974, 2012
Tang L, Joung B, Ogawa M, Chen PS, Lin SF. Intracellular Calcium Dynamics, Shortened Action Potential Duration, and Late-Phase 3 Early Afterdepolarization in Langendorff-Perfused Rabbit Ventricles. J Cardiovasc Electrophysiol 23(12):1364-1371, 2012
Machida M, Miura S, Matsuo K, Ishikura H, Saku K. Effect of intravenous adrenaline before arrival at the hospital in out-of-hospital cardiac arrest. Journal of Cardiology 60:503-507, 2012
Piccirillo G, Magri D, Pappada MA, Maruotti A, Ogawa M, Han S, Joung B, Rossi P, Nguyen BL, Lin SF, Chen PS. Autonomic nerve activity and the short-term variability of the Tpeak-Tend interval in dogs with pacing-induced heart failure Heart Rhythm Society 2044-2050, 2012
Ayaori M, Yakusiji E,Ogura M,Nakaya K,Hisada T,Uto-Kondo H,Takiguchi S,Terao Y,Sasaki M,Komatu T,Iizuka M,Yogo M,Uehara Y,Kagechika H,Nakanisi T,Ikewaki K Retinoic Acid receptor agonists regulate expression of ATP-binding cassette transporter G1 in macrophages. Biochimica et Biophysica Acta 1821(4):561-72, 2012
Morii J, Miura S, Shiga Y, Sugihara M, Arimura T, Sako H, Zhang B, Uehara Y, Saku K. Comparison of the efficacy and safety of irbesartan and olmesartan in patients with hypertension (EARTH study). Clin Exp Hypertens. 34(5):342-9, 2012
Shimizu T, Miura S, Takeuchi K, Tashiro T, Saku K. Effects of gender and aging in patients who undergo coronary artery bypass grafting: From the FU-Registry Cardiol J 19(6):618-24, 2012
Iwata A, Miura S, Tanaka T, Ike A, Sugihara M, Nishikawa H, Kawamura A, Saku K. Plasma pentraxin-3 levels are associated with coronary plaque vulnerability and are decreased by statin. Coron Artery Dis. 23(5):315-21., 2012
2011年
Takamiya Y, Miura S, Tsuchiya Y, Fukuda Y, Zhang B, Kuwano T, Ike A, Yanagi D, Kubota K, Mori K, Iwata A, Nishikawa H, Kawamura A, Miller N, Matsuo K, Shirai K, Saku K. Angiographic late lumen loss at the site of overlap of multiple CypherTM sirolimus-eluting stents: ALSOCE study. Journal of Cardiology 57(2):187-193 2011
Ike A, Nishikawa H, Shirai K, Mori K, Kuwano T, Fukuda Y, Takamiya Y, Yanagi D, Kubota K, Tsuchiya Y, Zhang B, Miura S, Saku K. Impact of Glycemic Control on the Clinical Outcome in Diabetic Patients With Percutaneous Coronary intervention - From the FU-Rsgistry -. Circulation Journal 75(4):791-799, 2011
Chua SK, Chang PC, Maruyama M, Turker I, Shinohara T, Shen MJ, Chen Z, Shen C, Rubart-von der Lohe M, Lopshire JC, Ogawa M, Weiss JN, Lin SF, Ai T, Chen PS. Small-conductance calcium-activated potassium channel and recurrent ventricular fibrillation in failing rabbit ventricles. Circ Res. 108:971-979 2011
Saku K, Zhang B, Noda K, The PATROL Trial Investigators. Randomized Head-to-Head Comparison of Pitavastatin, Atorvastatin, and, Rosuvastatin for Safety and Efficacy (Quantity and Quality of LDL) - The PATROL Trial - Circulation Journal. 75:1493-1505, 2011
Imaizumi S. Intestine may be a major site of action for the apoA-l mimetic peptide 4F whether administered subcutaneously or orally. Journal of Lipid Research 52:1200-1210, 2011
Imaizumi S. Human CYP2S1 Metabolizes Cyclooxygenase-and Lipoxygenase-Derived Eicossanoids. DRUG METAB DISPOS 39:180-190 2011
Imaizumi S L-5F, an apolipoprotein A-I mimetic inhibits tumor angiogenesis by suppressing VEGF/basic FGF signaling pathways. Integrative Biology 3:479-489 2011
Mitsutake R, Miura S, Shiga Y, Uehara Y, Saku K. Association Between Hypertension and coronary Artery Disease as Assessed by Coronary Computed Tomography. J of Clinical Hypertension 13(3):198-204, 2011
Kuwano T, Miura S, Shirai K, Ike A, Mori K, Shimizu T, Zhang B, Iwata A, Nishikawa H, Kawamura A, Saku K. Serum Levels of Bilirubin as an Independent Predictor of Coronary In-Stent Restenosis: A New Look at an Old Molecule. Journal of Atherosclerosis and Thrombosis 18(7):574-583 2011
Swaminathan PD, Purohit A, Soni S, Voigt N, Singh MV, Glukhov AV, Gao Z, He BJ, Kuczak ED, Joiner ML, Kutschke W, Yang J, Donahue JK, Weiss RM, Grumbach IM, Ogawa M, Chen PS, Efimov I, Dobrev D, Mohler PJ, Hund TJ, Anderson ME. Oxidized CaMKⅡ causes sinus node dysfunction in mice. J Clin Invest Equb ahead of print 2011
Takahira M, Noda K, Fukushima M, Zhang B, Mitsutake R, Uehara Y, Ogawa M, Kakuma T, Saku K. Randomized Double-Blind Controlled Comparative Trial of Food Containing Soy Protein vs.Milk Protein in Visceral Fat Obesity. -FLAVO Study- Circulation Journal 75(9):2235-2243 2011
Shiga Y, Miura S, Mitsutake R, Yamagishi S, Saku K. Significance of Plasma Levels of Pigment Epithelium-derived Factor as Determined by Multidetector Row Computed Tomography in Patients with Mild Chronic Kidney Disease and/ or Coronary Artery Disease. J Int Med Res. 39:(3)880-890 2011
Morgantini C, Natali A, Boldrini B, Imaizumi S, Nadab M, Fogelman AM, Ferrannini E, Reddy ST. Anti-inflammatory and Antioxidant Properties of HDLs Are lmpaired in Type 2 Diadetes. Diabetes 60(10):2617-23, 2011
Meriwether D, Imaizumi S, Grijalva V,Hough G, Vakili L, Anantharamaiah GM, Farias-Eisner R, Navab M, Fogelman AM, Reddy ST, Shechter I. Enhancement by LDL of transfer of L-4F and oxidized lipids to HDL in C57BL/6J mice and human plasma J Lipid Res 52(10):1795-809 2011
Kitajima K,Miura S, Yamagushi T, Uehara Y, Kiya Y, RyeKA, Kadowaki T, Saku K. Possibility of increasing cholesterol efflux by adiponectin and its receptors through the ATP binding cassette transporter A1 in HEK293T cells. Biochem Biophys Res Commun. 411:305-311 2011
Sugihara M, Miura S, Takamiya Y, Kiya Y, Arimura T, Iwata A, Kawamura A, Nishikawa H, Yamagishi S, Saku K. Significance of pigment spithelium-derived factor levels with angiotensin Ⅱ type 1 receptor blokers in patients with successful colonary stent implantation. J Renin Angiotensin Aldosterone Syst. 12:320-325 2011
Iwata A, Miura S, Morii J, Yamagishi S, Saku K. Association between plasma pigment epithelium-derived factor levels and tissue characteristics of coronary plaque using integrated backscatter intravascular ultrasound. Intern Med. 50:1889-1894 2011
Arimura T, Miura S, Sugihara M, Iwata A, Yamagishi S, Saku K. Association Between plasma levels of pigment epithelium-derived factor and renal dysfunction in patients with coronary artery disease. Cardiol J 18:515-520 2011
Iwata A, Miura S, Zhang B, Imaizumi S, Uehara Y, Shiomi M, Saku K. Antiatherogenic effects of newly-developed apolipoprotein A-I mimetic peptide/ phospholipid complexes against aortic plaque burden in Watanabe-heritable hyperlipidemic rabbits. Atherosclerosis 218:300-307 2011
Mito T, Miura S, Iwata A, Morii J, Sugihara M, Ike A, Mori K, Kawamura A, Nishikawa H, Zhang B, Saku K. Determination of the cut-off plasma adiponectin level assosiated with a lower risk of restenosis in patients with stable angina. Coronary Artery Dis. 22:451-457 2011
Shiga Y, Miura S, Morii J, Kuwano T, Mitsutake R, Uehara Y, Inoue A, Saku K. Comparison of the efficacy and safety of Single-pill fixed-dose combinations of Losartan / hydrochlorothiazide and Valsartan / hydrochlorothiazide in patients with hypertension (SALT-VAT study). Intern Med. 50(21):2477-2483 2011
Morito N, Miura S, Saku K. Changes in the baseline clinical characteristics of hospitalized patients with congestive heart failure. Med Bull Fukuoka Univ.(福岡大医学紀要) 38(4):171-176 2011
Saraswathi R, Sankar D, Ali A, Uehara Y, Abe S, Sambandam G, Rao MR. A Pilot Assessment of Oxidative Stress Byproducts and Antioxidant Activities Among Indian Patients with Various Stages of Hypertension. Clin Exp Hypertens 33(7):437-443, 2011
Baba Y, Higuchi MA, Fukuyama K, Abe H, Uehara Y, Inoue T, Yamada T. Effect of chronic kidney disease on excessive daytime sleepiness in Parkinson disease. Eur J Neurol 18(11):1299-303 2011
Serikawa T, Kawasaki T, Koga H, Orita Y, Ikeda S, Goto Y, Shintani Y, Kajiwara M, Tanaka H, Fukuyama T, Koga N. Late catch-up phenomenon associated with stent fracture after sirolimus-eluting stent implantation: incidence and outcome. J Interv Cardiol. 24(2):165-71 2011
Ozasa H, Ayaori M, Iizuka M, Terao Y, Uto-KOndo H, Yakushiji E, Takiguchi S, Nakaya K, Hisada T, Uehara Y, Ogura M, Sasaki M, Komatsu T, Horii S, Mochizuki S, Yoshimura M, Ikewaki K. Pioglitazone enhances cholesterol efflux from macrophages by increasing ABCA1/ACG1 expressions via PPARγ /LXRαpathway: findings from in vitro and ex vivo studies. Atherosclerosis 219:141-15, 2011
Arishima H, Matsunaga A, Uehara Y, Niimura H, Zhang B, Ohwaki K, Hayashida K, Yoshimizu K, Saku K. Statins Induce the Gene Expression of Apolipoprotein A5 in HepG2 Cells. Med.Bull.Fukuoka Univ.(福岡大学医学紀要) 38(4):161-169 , 2011
Fukuda Y, Miura S, Tsuchiya Y, InoueY, Kubota K, Takamiya Y, Kuwano T, Ohishi H, Ike A, Mori K, Yanagi D, Nishikawa H, Shirai K, Saku K, Urata H. Lower frequency of non-target lesion intervention in post-successful percutaneous coronary intervention patients with an LDL to HDL cholesterol ratio below 1.5. International Journal of Cardiology 149(1):120-122 2011
2010年
Miura SI, Saku K. Do angiotensin II type 1 receptor blockers have molecular effects? Hypertens Res. 2010; 33(2):105-106.
Miura SI, Matsuo Y, Kiya Y, Karnic SS, Saku K. Molecular mechanisms of the antagonistic action between AT(1) and AT(2) receptors. Biochem Biophys Res Commun. 2010; 391(1):85-90.
Takashima H, Kumagai K, Matsumoto N, Yasuda T, Nakashima H, Yamaguchi Y, Hida S, Muraoka S, Mitsutake C, Miura S, Saku K. Characteristics of the conduction of the left atrium in atrial fibrillation using non-contact mapping. Journal of Cardiology. 2010; 56,166-175.
Tobina T, Michishita R, Yamasawa F, Zhang B, Sasaki H, Tanaka H, Saku K, Kiyonaga A. Association between the angiotensin I-converting enzyme gene insertion/delition polymorphism and endurance running speed in Japanese runners. J Physiol Sci. 2010; 60:325-330.
Buga GM, Navab M, Imaizumi S, Reddy ST, Yetka B, Hough G, Anantharamaiah GM, Fogelman AM. L-4F, an Apolipoprotein A-Ⅰ Mimetic, Inhibits Platelet Aggregation and Prolongs Bleeding Time by Inhibiting the Formation of Arachidonic Acid Metabolites in Apo-E Null Mice. Arterioscler Thoromn Vasc Biol. 2010; 30(2):283-289.
Imaizumi S, Kiya Y, Miura S, Zhang B, Matsuo Y, Uehara Y, Rye KA, Saku K. Pharmacological intervention using reconstituted high-density lipoprotein changes in the lipid profile in spontaneously hypersensitive rats. Clin Exp Hypertens. 2010; 32(3):202-208.
Imaizumi S, Grijalva V, Navab M, Van Lenten BJ, Wagner AC, Anantharamiah GM, Fogelman AM, Reddy ST. L-4F differenrially alters plasma levels of oxidized fatty acids resulting in more anti-inflammatory HDL in mice. Drug Metab Lett. 2010; 4(3):139-48.
Imaizumi S, Grijalva V, Priceman S, Wu L, Su F, Farias-Eisner R, Hama S, Navab M, Fogelman AM, Reddy ST. Mitogen-activeted protein kinase phosphatase-1 deficiency decreases atherosclerosis in apolipoprotein E null mice by reducing monocyte chemoattractant protein-1 levels. Mol Genet Metab. 2010;
Morgantini C, Imaizumi S, Grijalva V, Navab M, Fogelman AM, Reddy ST. ApoA-ⅠMimetic Peptides Prevent Atherosclerosis Development and Reduce Plaque Inflammation In A Model of Diabetes. Diabetes. 2010;
Su F, Kozak K, Imaizumi S, Gao F, Amneus M, Grijalva V, Ng C, Wagner A, Hough G, Farias-Eisner G, Anantharamaiah GM, Van Lenten B, Fogelman AM, Reddy ST, Farias-Eisner R. ApoA-Ⅰ and apoA-Ⅰ Mimetic Peptide Inhibit Tumor Development in a Mouse Model of Ovarian Cancer. Proc Natl Acad Sci U S A. (in press). 2010;
Mitsutake C, Muraoka S, Takashima H, Nakashima H, Yasuda T, Matsumoto N, Kumagai K, Saku K. Does Atrial-Pacing from Different Intra-Atrial Sites for Atrial Fibrillation Effect Pulmonary Venous Pressure? Journal of Arrhythmia. 2010; 26(3):176-180.
Nishi N,Ogawa M, Morita H, Nakamura K, Banba K, Miura D, Kumagai N, Matsunaga A, Kawamura H, Urakawa S, Miyaji K, Nagai M, Satoh K, Nakagawa K, Tanaka M, Hiramatsu S, Tada T, Murakami M, Nagase S, Kohno K, Kusano KF, Saku K, Ohe T, Ito H. SCN5A Mutation Is Associated With Early and Frequent Recurrence of Ventricular Fibrillation in Patients With Brugada Syndrome. Circulation Journal. 2010; 74(12):2572-2578.
Yasuda T, Kumagai K, Ogawa M, Nakashima H, Zhang B, Miura S, Saku K. Comparison of the Effects of Na+ and K+ Channel Blockers on the Electrophysiological Properties of the Pulmonary Veins in Patienties with Atrial Fibrillation. Journal of Arrhythmia. 2010; 26(4):259-266.
Shiga Y, Miura S, Mitsutake R, Kawamura A, Uehara Y, Saku K. Significance of serum high-Density lipoprotein cholesterol levels for diagnosis of coronary stenosis as determined by MDCT in patients with suspected coronary artery disease. J Atheroscler Thromb. 2010; 17(8):870-878.
Fujino M, Miura S, Kiya Y, Tominaga Y, Matsuo Y, Karnik SS, Saku K. A small difference in the molecular structure of angiotensin II receptor blockers induces AT? receptor-dependent and -independent beneficial effects. Hypertens Res. 2010; 33:1044-1052.
Matsumoto N, Kumagai K, Ogawa M, Matsuo K, Yasuda T, Takashima H, Mitsutake C, Muraoka S, Matsunaga A, Miura S, Saku K. Efficacy of Additional Amiodarone Therapy in Patients with an Implantable Cardioverter-Defibrillator. J Arrhythmia. 2010; 26:103-110.
Miura S, Saku K. Is a blood pressure rise the only deleterious off-target effect of cholesterol ester transfer protein inhibitors? J Hypertens. 2010; 28(8):1614-1616.
Sankar D, Ali A, Raman S, Uehara Y, Ganapathy. Antioxidative capacity of hydrochlorothiazide and atenolol in long-term hypertention therapy. J Chin Clin Med. 2010; 5(3):123-129.
Azekoshi Y, Yasu T, Watanabe S, Tagawa T, Abe S, Yamakawa K, Uehara Y, Momomura S, Urata H, Ueda S. FFA causes leukocyte activation and resultant endothelial dysfunction through enhanced angiotensinⅡ production in mononclear and polymorphonuclear cells. Hypertention. 2010; 56(1):136-142.
Akazawa H, Yasuda N, Miura S, Komuro I. Assessment of inverse agonism for the angiotensin II type 1 receptor. Methods Enzymol. 2010; 485:25-35.
Fujimi K, Uehara Y, Abe S, Kawamura A, Devarajan S, Miura SI, Saku K, Urata H. Homocysteine-induced oxidative stress upregulates chymase in mouse mastocytoma cells. Hypertens Res. 2010; 33:149-154.
Fukuda Y, Shirai K, Zhang B, Miller N, Takamiya Y, Kuwano T, Yanagi D, Ike A, Mori K, Kubota K, Iwata A, Nishikawa H, Kawamura A, Costantini CO, Costantini CR, Miura S, Saku K. Factors that Predict Target Lesion Revascularization in Patients with Paclitaxel-eluting Stent Implantation. Medical bulletin of Fukuoka University. 2010; 37(1):1-6.
Tsukahara H, Noda K, Saku K. A Randomized Controlled Open Comparative Trial of Varenicline vs Nicotine Patch in Adult Smokers・-Efficacy,Safety and Withdrawal Symptoms (The VN-SEESAW study)-. Circulation Journal. 2010; 74(4):771-778.
Wei CC, HaseN, Inoue Y, Bradley EW, Yahiro E, Li M, Naqvi N, Powell PC, Shi K, Takahashi Y, Saku K, Urata H, Dell'ltali. Mast cell chymase limits the cardiac efficacy of Ang l-converting enzyme inhibitor therapy in rodents. The Jounal of Clinical Investigation. 2010; Epub ahead of print.
Oniki K, Adachi R, Ando S, Uehara Y, Zhang B, Saku K. Syntfesis of a Peptide Removing Cholesterol from Cell and Its Ability of HDL Formation in Blood Plasma. The Japanese Peptide Society. 2010; 281-284.
Kiya Y, Miura S, Fujino M, Imaizumi S, Karnik SS, Saku K. Clinical and Pharmacotherapeutic Relevance of the Double-Chain Domain of the Angiotensin II Type 1 Receptor Blocker Olmesartan. Clinical and Experimental Hypertension. 2010; 32:129-136.
Miura S, Saku K. ReviewEffects of statin and lipoprotein metabolism in heart failure. JOURNAL of CARDIOLOGY. 2010; 55:(3)287-290.
Yamaguchi Y, Kumagai K, Nakashima H, Saku K. Long-Term Effects of Box Isolation on Sympathovagal Balance in Atrial Fibrillation. Circulation Journal. 2010; 74(6):1096-1103.
Atsushi Ishi, Bo Zhang, Sunao Kaneko, Shinichi Hirose. Positive association between benign familial infantile convulsions and LG14. BRAIN & DEVELOPMENT. 2010; 32(7) :538-43.
2009年
Miura S,Fujino M,Karnik SS,Saku K. Angiotensin Progress. Differential pharmacotherapeutic effects of angiotensin II type 1 receptor blockers. Nova Science Publishers. 2009; 221-234.
Fukuda Y, Shirai K, Miura S, Ike A, Takamiya Y, Kuwano T, Yanagi D, Mori K, Kubota K, Miller N, Nishikawa H, Zhang B, Saku K. The impact of angulated lesions on angiographic late loss in patients with drug-eluting stent implantation. Journal of Cardiology. 2009; 53:396-401.
Sugihara M, Miura S, Takamiya Y, Kiya Y, Arimura T, Iwata A, Kawamura A, Nishikawa H, Uehara Y, Saku K. Safety and efficacy of antihypertensive therapy with add-on angiotensin II type 1 receptor blocker after successful coronary stent implantation. Hypertension Research. 2009; 32:625-630.
Takamiya Y, Miura S, Kawamura A, Tanigawa H, Zhang B, Iwaata A, Nishikawa H, Matsuo K, Shirai K, Saku K. Intensive lowering of blood pressure and low-density lipoprotein cholesterol with statin therapy may improve neointimal formation after coronary stenting in patients with coronary artery disease(LOBOCOP). Coron Artery Dis. 2009; 20(4):288-294.
Sako H, Miura S, Kumagai K, Saku K. Association between Augmentation Index and Severity of Atheroma or Aortic Stiffness of the Descending Thoracic Aorta by Transesophageal Echocardiography. Circ J. 2009; 73(6):1151-1156.
Kiya Y,Miura SI,Imaizumi S,Uehara Y,Matsuo Y,Abe S,Jimi S,Urata H, Rye KA,Saku K. Reconstituted high-density lipoprotein attenuates postinfraction left ventricular remodeling in rats. Atherosclerosis. 2009; 203(1):137-144.
MitsutakeR,Miura S, Kawamura A, Saku K. Are Metabolic Factors Associated With Coronary Artery Stenosis on MDCT ?. Circulation Journal. 2009; 73(1):132-138.
Miura S,Saku K. Angiotensin II Type 1 Receptor Blocker Combined with Calcium Channel Blocker for the Treatment of Obese Hypertensive Patients. INTERNAL MEDICINE. 2009; 48(1):1-2.
Kimura K,Miura S,Iwata A,Sugihara M,Arimura T,Nishikawa H, Kawamura A,Saku K. Association between cardiac function and metabolic factors including adiponectin in patients with acute myocardial infarction. Journal of Cardiology. 2009; 53(1):65-71.
Miyachi K,Hankins RW,Uehara Y,Zhang B,Saku K,Homma Y,Shigematu H,MIkoshiba K. A Postmenopausal Patient with Tangier Disease Developing Sjogren's Syndrome. J Rheumatol. 2009; 36(1):208-9.
Furuyama S,Uehara Y,Zhang B,Baba Y,Abe S,Iwamoto T, Miura S,Saku K. Genotypic effect of ABCG1 gene promoter-257T>G polymorphism on coronary artery disease severity in Japanese men. J Atheroscler Thromb. 2009; 16;194-200.
Kitajima K,Miura S,Matsuo Y,Uehara Y,Saku K. Newly developed PPAR-α agonist (R)-K-13675 inhibits the secretion of inflammatory markers without affecting cell proliferation or tube formation. Atherosclerosis. 2009; 203(1):75-81.
Yamashita T,Ogawa S, Sato T, Aizawa Y, Atarashi H, Fujiki A, Inoue H, Ito M, Katoh T, Kobayashi Y, Koretsune Y, Kumagai K, Niwano S, Okazaki O,Okamura K, Saku K, Tanabe T, Origasa H for the J-BAF Investigators. Dose-Response Effects of Bepridil in Patients With Persistent Atrial Fibrillation Monitored With Transtelephonic Electrocardiograms ― A Multicenter, Randomized, Placebo-Controlled, Double-Blind Study (J-BAF Study) ―. Circulation Journal. 2009; 73(6):1020-1027.
Mitsutake R, Miura S, Iwata A, Saku K. Aneurysms of right-sided descending aorta associated with right-sided aortic arch detected by 64-multidetector-row Computed Tomography. Intern Med. 2009; 48(7):575-576.
Mitsutake R, Miura S, Tanaka T, Matsuo K, Saku K. Coronary artery aneurysm with thrombus evaluated by multi-detector row computed tomography. Intern Med. 2009; 48(5):339-41.
Mitsutake R, Miura SI, Zhang B, Saku K. HDL-associated factors provide additional prognostic information for coronary artery disease as determined by multi-detector row computed tomography. Int J Cardiol. 2009; Epub ahead of print.
Kimura T, et al (Saku K) J-Cypher Resistry Investigators. Antiplatelet therapy and stent thrombosis after sirolimus-eluting stent implantation. Circulation. 2009; 119(7):987-995.
Zhang B, Matsunaga A, Rainwater DL, Miura SI, Noda K, Nishikawa H, Uehara Y, Shirai K, Ogawa M, Saku K. Effects of ROSuvastatin on electronegative LDL as characterized by CapillARY isotachophoresis: The ROSARY study. J Lipid Res. 2009; 50:1832-1841.
Miura S,Fujino M,Karnik SS,Saku K. Angiotensin Progress. Differential pharmacotherapeutic effects of angiotensin II type 1 receptor blockers. Nova Science Publishers. 2009; 221-234.
Fukuda Y, Shirai K, Miura S, Ike A, Takamiya Y, Kuwano T, Yanagi D, Mori K, Kubota K, Miller N, Nishikawa H, Zhang B, Saku K. The impact of angulated lesions on angiographic late loss in patients with drug-eluting stent implantation. Journal of Cardiology. 2009; 53(3):396-401.
Sugihara M, Miura S, Takamiya Y, Kiya Y, Arimura T, Iwata A, Kawamura A, Nishikawa H, Uehara Y, Saku K. Safety and efficacy of antihypertensive therapy with add-on angiotensin II type 1 receptor blocker after successful coronary stent implantation. Hypertension Research. 2009; 32(7):625-630.
Takamiya Y, Miura S, Kawamura A, Tanigawa H, Zhang B, Iwaata A, Nishikawa H, Matsuo K, Shirai K, Saku K. Intensive lowering of blood pressure and low-density lipoprotein cholesterol with statin therapy (LOBOCOP) may improve neointimal formation after coronary stenting in patients with coronary artery disease. Coron Artery Dis. 2009; 20(4):288-294.
Sako H, Miura S, Kumagai K, Saku K. Association between Augmentation Index and Severity of Atheroma or Aortic Stiffness of the Descending Thoracic Aorta by Transesophageal Echocardiography. Circ J. 2009; 73(6):1151-1156.
Piccinillo G, Magri D, Ogawa M, Song J, Chong VJ, Han S, Joung B, Choi EK, Hwang S, Cheng LS, Lin SF, Chen PS. Autonomic Nervous System Activity Measured Directly and QT Interval Variability in Normal and Pacing-Induced Tachycardia Heart Failure Dogs. J Am Coll Cardiol. 2009; 54(9):840-50.
Ogawa M, Zhoug S, Tan AY, Fishbein MC, Lin SF, Chen LS, Chen PS. What have we learned about the contribution of autonomic nervous system to human arrhythmia ?. Heart Rhythm. 2009; 6(8Supple):S8-11.
Ogawa M, Morita N, Tang L, Karagueuzian HS, Weiss JN, Lin SF, Chen PS. Mechanisms of recurrent ventricular fibrillation in a rabbit model of pacing-induced heart failure. Heart Rhythm. 2009; 6(6):784-92.
Piccirillo G, Ogawa M, Song J, Chong VJ, Joung B, Han S, Magri D, Chen LS, Lin SF, Chen PS. Power spectral analysis of heart rate variability and autonomic nervous system activity measured directly in healthy dogs and dogs with tachycardia-induced heart failure. Heart Rhythm. 2009; 6(4):546-52.
Arimura T, Mitsutake R, Miura S, Nishikawa H, Kawamura A, Saku K. Acute Myocardial Infarction Associated with Pregnancy Successfully Treated with Percutaneous Coronary Intervention. Internal Medicine. 2009; 48:1383-1386.
Qin Y, Yasuda N, Akazawa H, Ito K, Kudo Y, Liao CH, Yamamoto R, Miura S, Saku K, Komuro I. Multivalent ligand-receptor interactions elicit inverse agonist activity of AT1 receptor blockers against stretch-induced AT1 receptor activation. Hypertension Research. 2009; 32(10):875-883.
Fukuda Y, Miura S, Zhang B, Iwata A, Kawamura A, Nishikawa H, Shirai K, Saku K. Significance of Urinary Liver-fatty Acid-binding Protein in Cardiac Catheterization in Patients with Coronary Artery Disease. INTERNAL MEDICINE. 2009; 48:1731-1737.
Miura S, Saku K. Do Angiotensin-converting Enzyme Inhibitors and Angiotensin II Receptor Blockers Have Similar Effects in the Improvement of Left Ventricular Dysfunction after Myocardial Infarction in Japanese?. INTERNAL MEDICINE. 2009; 48:1929-1930.
Kumagai N, Mitsutake R, Miura S, Kawamura A, Takamiya Y, Nishikawa H, Uehara Y, Saku K. Acute colonary syndrome associated with essential thrombocythemia. J Cardiol. 2009; 54(3):485-489.
Miura S, Saku K. Do angiotensin II type 1 receptor blockers have molecular effects?. Hypertens Res. 2009; Epub ahead of print.
Miura S, Matsuo Y, Kiya Y, Karnic SS, Saku K. Molecular mechanisms of the antagonistic action between AT(1) and AT(2) receptors. Biochem Biophys Res. 2009; Epub ahead of print.
Mitsutake R, Miura S, Shiga Y, Iwata A, Saku K. Coronary-pulmonary artery fistula with anomalous vessels arising from the right coronary sinus detected by 64-MDCT. Intern Med. 2009; 48(21):1893-1896.
Koike T, Kitajima S, Yu Y, Li Y, Nishijima K, Liu E, Sun H, Waqar AB, Inoue T, Wang Y, Zhang B, Kobayashi J, Morimoto M, Saku K, Watanabe T, Fan J. Expression of human apoAII in transgenic rabbits leads to dyslipidemia: a new model for combined hyperlipidemia. Arterioscler Thromb Vasc Biol. 2009; 29(12):2047-2053.
Kumagai N, Mitsutake R, Miura S, Kawamura A, Takamiya Y, Nishikawa H, Uehara Y, Saku K. Acute coronary syndrome associated with essential thrombocythemia. Journal of Cardiology. 2009; 54:485-489.
Tanigawa H, Billheimer JT, Tohyama J, Fukui IV, Ng DS, Rothblat GH, Rader DJ. Lecithin:Cholesterol Acyltransferase Expression Has Minimal Effects on Macrophage Reverse Cholesterol Transport In Vivo. Circulation. 2009; 120:160-169.
Ogawa M, Tan AY, Song J, Kobayashi K,Fishbein MC,Lin SF,Chen LS,Chen PS. Cryoablation of stellate ganglia and atrial arrhythmia in ambulatory dogs with pacing-induced heart failure. Heart Rhythm. 2009; 6(12):1772-9.
Joung B, Ogawa M, Lin SF, Chen PS. The Calcium and voltage Clocks in sinoatrial node automaticity. Korean Circ J. 2009; 39(6):217-22.
Bhuiyan MA, Ishiguro M, Hossain M, Nakamura T, Ozaki M, Miura S, Nagatomo T. Binding sites of valsartan, candesartan and losartan with angiotensin II reseptor 1 subtype by molecular modeling. Life Sci. 2009; 85:136-140.
Bhuiyan MA, Hossain M, Miura S, Nakamura T, Ozaki M, Nagatomo T. Constitutively active mutant N111G of angiotensin II type 1(AT1) receptor induced homologous internalization through mediation of AT1 -receptor antagonist. J Pharmacol Sci. 2009; 111:227-234.
2008年
Miura S,Kiya Y,Kanazawa T,Imaizumi S,Fujino M,Matsuo Y,Karnik S,Saku K. Differential Bonding Interactions of Inverse Agonists of AngiotensinII Type1 Receptor in Stabilizing the Inactive State. Molecular Endocrinology. 2008; 22(1):139-146.
Li M,Naqvi N,Yahiro E,Liu K,Powell P,Bradley E,Martin D,Graham R,Dell'Italia L,Husain A. c-Kit Is Required for Cardiomyocyte Terminal Differentiation. Circulation Research. 2008; March 28.
Morito N,Inoue Y,Urata M,Yahiro E,Kodama S,Fukuda N,Saito N,Tsuchiya Y,Mihara H,Yamanouchi Y,Saku K,Urata H. Increased carotid artery plaque score is an independent predictor of the presence and severity of coronary artery disease. Journal of Cardiology. 2008; 51(1):25-32.
Miura S,Saku K. Do Statins Need to be Prescribed for All Patients with Left Ventricular Dysfunction? INTERNAL MEDICINE. 2008; 47:335-336.
Mitsutake R,Miura S,Nishikawa H,Saku K. Usefulness of the evaluation of stent fracture by 64-multi-detector row computed tomography. Journal of Cardiology. 2008; 51(2):135-138.
Yanagi D,Shirai K,Takamiya Y,Fukuda Y,Kuwano T,Ike A,Mori K,Kubota K,Iwata A,Fujimi K,Miller N,Zhang B,Tsuchiya Y,Urata H,Saku K. Results of provisional stenting with a Sirolimus-eluting stent for bifurcation lesion:Multicenter study in Japan. Journal of Cardiology. 2008; 51(2):89-94.
Mitsutake R,Miura S,Sako H,Nishikawa H,Saku K. Usefulness of multi-detector row computed tomography for the management of percutaneous transluminal septal myocardial ablation in patient with hypertrophic obstructive cardiomyopathy. International Journal of Cardiology. 2008; 129(2):e61-63.
Inoue Y,Zhang B,Sadamori R,Shirota K,Saku K,Kawarabayashi T. Changes in lipid metabolism in postmenopausal Japanese women using hormone therapy evaluated by capillary isotachophoresis: a pilot study. Menopause. 2008; 15(1):157-163.
Uehara Y,Tsuboi Y,Zhang B,Miura S,Baba Y,higuchi MA,Yamada T,Rye KA,Saku K. POPC/apo-A I discs as a potent lipoprotein modulator in Tangier disease. Atherosclerosis. 2008; 197(1):283-289.
Sako H,Miura S,Iwata A,Nishikawa H,Kawamura A,Matsuo K,Shirai K,Saku K. Changes in CCR2 Chemokine Receptor Expression and Plasma MCP-1 Concentration after the Implantation of Bare Metal Stents Versus Sirolimus-eluting Stents in Patients with Stable Angina. INTERNAL MEDICINE. 2008; 47(1):7-13.
Mitsutake R,Shirai K,Nishikawa H,Saito N,Miura S,Saku K. Calcified Occlusion of the Coronary Arteries in a Young Woman Diagnosed with Kawasaki Disease. INTERNAL MEDICINE. 2008; 47:559-560.
Zhang B,Miura S,Yanagi D,Noda K,Nishikawa H,Matsunaga A,Shirai K,Iwata A,Yoshinaga K,Adachi H,Imaizumi T,Saku K. Reduction of charge-modified LDL by statin therapy in patients with CHD or CHD risk factors and elevated LDL-C levels:The SPECIAL Study. ATHEROSCLEROSIS. 2008; 201(2):353-359.
Miura S,Matsuo Y,Saku K. Jun N-Terminal Kinase Inhibitor Blocks Angiogenesis by Blocking VEGF Secretion and an MMP Pathway.Journal of Atherosclerosis and Thrombosis. 2008; 15(2):69-74.
Imaizumi S,Miura S,Nakamura K,Kiya Y,Uehara Y,Zhang B,Matsuo Y,Urata H,Ideishi M,Rye K,Sata M,Saku K. Antiarrhythmogenic Effect of Reconstituted High-Density Lipoprotein Against Ischemia/Reperfusion in Rats. Journal of the American College of Cardiology. 2008; 51(16):1604-1612.
Takamiya Y,Shirai K,Fujino M,Miller N,Tsuchiya Y,Okabe M,Saku K. Purulent pericarditis with salmonella enteritidis in a patient with CD4/CD8 depression. Journal of Cardiology. 2008; 51(3):201-204.
Fukuda Y,Shirai K,Takamiya Y,Nathan M,Mito T,Yanagi D, Hida S,Iwata A,Yasuda T,Zhang B,Nishikawa H,Ideishi M,Saku K. Isolated pulmonary arterial stenosis caused by Takayasu's arteritis in an elderly male. Journal of Cardiology. 2008; 51(3):196-200.
Miura S,Kawamura A,Saku K. Efficacy and Safety of Drug-eluting Stents in Long-term Follow-up. INTERNAL MEDICINE. 2008; 47:987-988
Miura S,Saku K. Angiotensin II Type 1 Receptor Brocker Combined with Hydrochlorothiazide for the Treatment of Hypertension. INTERNAL MEDICINE. 2008;47(13):1163-1164.
Bai H,Liu R,Liu Y,Saku K, Liu B. Distribution and effect of apo A-IV genotype on plasma lipid and apolipoprotein levels in a Chinese population. Acta Cardiology. 2008; 63(3):315-322.
Uehara Y,Yamada T,Baba Y,Miura S,Abe S,Kitajima K,Higuchi M,Iwamoto T,Saku K. ATP-binding cassette transporter G4 is highly expressed in microglia in Alzheimer's brain. BRAIN RESEARCH. 2008; 1217(2008):239-246.
Miura S,Saku K. Beneficial effects of ezetimibe-based therapy in patients with dyslipidemia. Journal of Cardiology. 2008; 52(1):1-6
Sako H,Miura S,Saku K. Significance of changes in plasma adiponectin concentration after the implantation of stents in patients with stable angina. Journal of Cardiology. 2008; 52(1):17-23
Miura S, Saku K. Ezetimibe, a Selective Inhibitor of the Transport of Cholesterol. INTERNAL MEDICINE. 2008; 47(13):1165-1170.
Zhou S, Tan AY, Paz O, Ogawa M, Chou CC, Hayashi H, Nihei M, Fishbein, MC, Chen LS, Lin SF, Chen PS. Antiarrhythmic Effects of Beta3-Adrenergic Receptor Stimulation in a Canine Model of Ventricular Tachycardia.Heart Rhythm. 2008; 5: 289-297.
Ogawa M, Lin SF, Weiss JN, Chen PS. Calcium Dynamics and Ventricular Fibrillation. Circ Res.. 2008; 102: e52.
Tang L, Hwang GS, Hayashi H, Song J, Ogawa M, Kobayashi K, Joung B, Karagueuzian HS, Chen PS, Lin SF. Intracellular Calcium Dynamics at the Core of Endocardial Stationary Spiral Waves in Langendorff-Perfused Rabbit Hearts. Am J Physiol Heart Circ Physiol. 2008; 295:H297-304.
Tan AY, Zhou S, Jung BC, Ogawa M, Chen LS, Fishbein MC, Chen PS. Ectopic Atrial Arrhythmias Arising from Canine Thoracic Veins During In-vivo Stellate Ganglia Stimulation. Am J Physiol Heart Circ Physiol. 2008; 295 : H691-8.
Tan AY, Zhou S, Ogawa M, Song J, Chu M, Li H, Fishbein MC, Lin S-F, Chen LS, Chen P-S. Neural Mechanism of Paroxysmal Atrial Fibrillation and Paroxysmal Atrial Tachycardia in Ambulatory Canines. Circulation. 2008; 118:916-25.
Yanagi D,Shirai K,Arimura T,Saito N,Mitsutake T,Mitsutake R,Hida S,Iwata A,Nishikawa H,Kawamura A,Miura S,Saku K. Left Ventricular Oozing Rupture following Acute Myocardial Infarction. INTERNAL MEDICINE. 2008; 47:1803-1805
Miura S,Saku K. Higher Plasma Levels of Adiponectin in Hemodialysis Patients: Good or Bad? INTERNAL MEDICINE. 2008; 47:1825-1826
Miura S,Saku K. Which strategy is more effective for the treatment of cardiovascular disease: high-dose angiotensin II type 1 receptor antagonist monotherarpy or combination therapy? American Journal of Cardiovascular Drugs. 2008; 8(2):88-90.
Kuwano T,Miura S,Nishikawa H, Shirai K,Saku K. Venous Thrombosis Associated with a Large Uterine Myoma. INTERNAL MEDICINE. 2008; 47(8):809.
Mitsutake R,Miura S,ShigaY,Kawamura A,Saku K. Is Chronic Kidney Disease Associated with Coronary Artery Stenosis or Calcification as Assessed by Multi-detector Row Computed Tomography? INTERNAL MEDICINE. 2008; 47(21):1835-41.
Iwata A,Miura S,Mori K,Kawamura A,Nishikawa H,Saku K. Associations between Metabolic Factors and Coronary Plaque Growth or Arterial Remodeling as Assessed by Intravascular Ultrasound in Patients with Stable Angina. Hypertension Research. 2008; 31(10):1879-1886.
Zhang B, Matsunaga A, Rainwater DL, Miura SI, Noda K, Nishikawa H, Uehara Y, Shirai K, Ogawa M, Saku K. Effects of ROSuvastatin on electronegative LDL as characterized by CapillARY isotachophoresis: The ROSARY study. J Lipid Res. 2008; Epub ahead of print.
Tolle M, Pawlak A, Schuchardt M, Kawamura A, Tietge UJ, Lorkowski S, Keul P, Assmann G, Chun J, Levkau B, van der Giet M, Nofer JR.. HDL-associated lysosphingolipids inhibit NAD(P)H oxidase-dependent monocyte chemoattractant protein-1 production. Arterioscler Thromb Vasc Biol. 2008; 28(8):1542-1548.
2007年
Iwata A,Miura S,Imaizumi S,Kiya Y,Nishikawa H,Zhang B,Shimomura H,Saku K. Do Valsartan and Losartan Have the Same Effects in the Treatment of Coronary Artery Disease? Circulation Journal. 2007; 71(1):32-38.
Niimura H,Mito T,Matsunaga A,Koga S,Akasu K,Morishige N,Tashiro T,Saku K. Left Ventricular Pseudoaneurysm Following Acute Myocardial Infarction. INTERNAL MEDICINE. 2007; 1221-1223.
Okamura K,Miura S,Zhang B,Uehara Y,Matsuo K,Kumagai K,Saku K,.Ratio of LDL-to HDL-Associated Platelet-Activating Factor Acetyihydrolase may be a Marker of Inflammation in Patients With Paroxysmal Atrial Fibrillation. Circulation Journal. 2007;71(2):214-219.
Yanagi D,Shirai K,Mori K,Ike A,Costantini O,Costantini R,Nishikawa H,Miller N,Zhang B,Tsuchiya Y,Urata H,Saku K. Possible Predictors of Target Lesion Revascularization After Drug-Eluting Stent Implantation.Journal of Cardiology.2007; 49(2):63-67.
Nishio M,Noda K,Matsuzaki M,Satoh T,Morita E,Asada R,Takahira M,Hosoi K,Saku K. pre-Information for Participants in Clinical Trials Provided to Medical Doctors other than the Clinical Investigators as Required by Clause 45 of the Welfare Ministerial Ordinance Number28 of 27 March 1997. 2007; 34(1):23-28.
Zhang B,Bottcher A,Imaizumi S,Noda K,Schmitz G,Saku K. Relation between charge-based apolipoprotein B-containing lipoprotein subfractions and remnant-like particle cholesterol levels. ATHEROSCLEROSIS. 2007; 191(1):153-161.
Uehara Y,Miura S,Eckardstein A,Abe S,Fujii A,Matsuo Y,Rust S,Lorkowski S,Assmann G,Yamada T,Saku K. Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1(ABCG1) and ABCA1 genes via an LXR/RXR responsive element. ATHEROSCLEROSIS. 2007; 191:11-21.
Zhang B,Saku K. Control of matrix effects in the analysis of urinary F2-isoprostanes using novel multidimensional solid-phase extraction and LC-MS/MS. Journal of Lipid Research. 2007; 48(3):733-744.
Miura S,Saku K. Therapies for Raising High-density Lipoprotein Cholesterol. INTERNAL MEDICINE. 2007; 46(7):339-340.
Matsunaga A,Arishima H,Niimura H,Zhang B,Uehara Y,Ohwaki K,Morita M,Hayashida K,Saku K. Strong Linkage Disequilibrium and Association of-1131T>C and c.553G>T Polymorphisms of the Apolipoprotein A5 Gene With Hypertriglyceridemia in a Japanese Population. Circulation Journal. 2007; 71(5):746-752.
Sakai T,Saku K. A health-economic evalution of aspirin: primary prevention and cardiovascular disease. INTERNAL MEDICINE. 2007; 46(8):431-433.
Zhang B,Uehara Y,Hida S,Miura S,Rainwater D,Segawa M,Kumagai K,Rye K,Saku K. Effects of apoA-I/phosphatidylcholine discs on charge-based LDL subfractions as characterized by capillary isotachophoresis. J Lipid Res. 2007; 48:1175-1189.
Sumi M,Miura S,Rye K,Toya N,Kanaoka Y,Yanaga K,Ohki T,Saku K,Nagai R. Reconstituted high-density lipoprotein stimulates differentiation of endothelial progenitor cells and enhances ischemia-induced angiogenesis, Arterioscler Thromb Vasc Biol. 2007; 27(4):813-818.
Iwata A,Miura S,Shirai K,Kawamura A,Tomita S,Matsuo Y,Zhang B,Nishikawa H,Kumagai K,Matsuo K,Saku K. Lower Level of Low-density Lipoprotein Cholesterol by Statin Prevents Progression of Coronary Restenosis after successful Stenting in Acute Myocardial Infarction. INTERNAL MEDICINE. 2007; 45(15):885-890.
Kumagai K. Upstream Therapy for Atrial Fibrillation. Circulation Journal. 2007; 71(A):75-81.
Takamiya Y,Miura S,Sako H,Shirai K,Morishige N,Tashiro T,Saku K. Pseudoaneurysm of the Mitral-Aortic Intervalvular Fibrosa Following Infective Endocarditis in a Patient With Acute Heart Failure:A Case Report. Journal of Cardiology. 2007; 49(6):353-356.
Mitsutake R,Miura S,Okamura K,Niimura H,Kawamura A,Saku K. Successful Intensive Lipid-lowering Therapy Using Atorvastatin Stabilizes Coronary Artery Plaque as Assessed by Multi-detector Row Computed Tomography. INTERNAL MEDICINE. 2007; 46(12):859-863.
Yamaguchi Y,Tsugawa H,Fujioka N,Kaseno K,Kitayama M,Kajinami K. Role of a Novel Conduction Pattern Around the Coronary Sinus in Cavotricuspid Isthmus Dependent Right Atrial Flutter. Journal of Cardiology. 2007; 50(1):1-10.
Miura S,Saku K. Regulation of Angiogenesis and Angiogenic Factors by Cardiovascular Medications. Current Pharmaceutical Design. 2007; 13(20):2113-2117.
Miura S,Saku K. Do all angiotensinII type1 recepter blockers have the same beneficial effects? British Journal of Pharmacology. 2007; 151(7):912-913.
Saku K. Circulation Journal Editorial Bosrd. Circulation Journal. 2007.
Mitsutake R,Miura S,Nishikawa H,Saku K. Left Main Trunk Coronary Stenosis in an Angina Patient With Low Coronary Risk Factors Assessed by Multi-Detector Row Computed Tomography. Journal of Cardiology. 2007; 50(3):219-221.
Iwata A,Miura S,Imaizumi S,Zhang B,Saku K. Measurement of Atherosclerotic Plaque Volume in Hyperlipidemic Rabbit Aorta by Intravascular Ultrasound. Journal of CARDIOLOGY . 2007; 50(4):229-234.
Hagiwara M,Yamagata K,Matsunaga T,Arakawa Y,Usui J,Shimizu Y,Aita K,Nagata M,Koyama A,Zhang B,Mastunaga A,Saku K,Saito T. A novel apolipoprotein E mutation,ApoE Tsukuba(Arg114Cys) in lipoprotein glomerulopathy. Nephrol Dial Transplant. 2007; 23(1):381-384.
Murakami K,Uehara Y,Abe T,Inoue Y,Ideishi M,Saku K,Urata H. Positive Correlation Between Chymase-Like Angiotensin II-Forming Activity in Mononuclear Cells and Serum Cholesterol Level. Journal of Cardiology. 2007; 50(5):291-298.
Nakashima H,Kumagai K. Reverse-Remodeling Effects of AngiotensinII Type1 Receptor Blocker in a Canine Atrial Fibrillation Model. Circulation Journal. 2007; 71(12):1977-1982.
Muraoka S,Mitsutake C,Takashima H,Nakashima H,Yasuda T,Matsumoto N,Kumagai K,Saku K. Efficacy and Safety of Catheter Ablation for Persistent or Permanent Atrial Fibrillation. Journal of Arrhythmia. 2007; 23(3):229-235.
Kawamura A,Baitsch D,Telgmann R,Feuerborn R,Weissen G,Hagedorn C,Saku K,Herrmann B,Eckardstein,Assmann G,Nofer J. Apolipoprotein E Interrupts Interleukin-1β Signaling in Vascular Smooth Muscle Cells. Arterioscler Thromb Vasc Biol. 2007; 27(7):1610-1617.
Sakai T. Assesssment of DPC implemented to improve the cost-effectiveness,the foundation of health insurance association,and the quality of health care. INTERNAL MEDICINE. 2007; 1-76.
Mitsutake R,Miura S,Saku K. Association between Coronary Artery Calcification Score as Assessed by Multi-detector Row Computed Tomography and Upstroke Time of Pulse Wave. INTERNAL MEDICINE. 2007; 46(22):1833-1836.
Ogawa M,Kumagai K,Vakulenko T,Yasuda T,Siegerman C,Garfinkel A,Chen PS,Saku K. Reduction of P-wave duration and successful pulmonary vein isolation in patients with atrial fibrillation. Journal of Cardiovascular Electrophysiol. 2007; 18(9):931-938.
Zhang B,Uehara Y,Hida S,Rainwater DL,Segawa M,Kumagai K,Rye KA,Saku K. Effects of reconstituted HDL on charge-based LDL subfractions as characterized by capillary isotachophoresis. Journal of Lipid Research. 2007; 48(5):1175-1189.
Senanayake P,Drazba J,Shadrach K,Milsted A,Rungger-Brandle E,Nihiyama K,Miura S,Karnik SS,Sears JE,Hollyfield JG. AngiotensinII and Its Receptor Subtypes in the Human Retina. Invest Ophtalmol Vis Sci. 2007; 48:3301-3311.
Miura S,Saku K. Reconstituted or recombinant high-density Iipoprotein is a therapeutic strategy for the treatment of atherisclerotic cardiovascular diseases. Fukuoka University. 2007; 4-7.
Miura S,Saku K. Treatment of cardiovascular disease using angiotensinII type 1 receptor blocker:a current perspective. Fukuoka University. 2007; 8-11.
Saku K. Molecular Mechanisms in Atherosclerotic Cardiovascular Disease,and the Development of New Therapeutic Strategies for Atherosclerosis. 2007.
Kumagai K,Muraoka S,Mitsutake C,Takashima H,Nakashima H. A New Approach Complete Isolation of the Posterior Left Atrium Including Pulmonary Veins for Atrial Fibrillation. Journal of Cardiovascular Electrophysiology. 2007; 18(10):1047-1052.
Saku K. Internal Medicine2007SanDiego,CA. Japan Chapter GOVERNOR'S NEWSLETTER. 2007; 6.
Ogawa MZhou S,Tan AY,Song J,Gholmieh G,Fishbein MC,Luo H,Siegel RJKarageuzian HS,Chen LS,Lin SF,Chen PS. Left Stellate Ganglion and Vagal Nerve Activity and Cardiac Arrhythmias in Ambulatory Dogs with Pacing-Induced Congestive Heart Failure. J Am Coll Cardiol. 2007; 24;50:335-343.
Ogawa M, Kumagai K, Vakulenko M, Yasuda T, Siegerman C ,Garfinkel A, Chen PS, Saku K. Reduction of P-wave Duration and Successful Pulmonary Vein Isolation in Patients With Atrial Fibrill.ation. J Cardiovasc Electrophysiol. 2007; 18:931-938.
2006年
Niimura H, Mito T, Matsunaga A, Koga S, Akasu K, Morishige N, Tashiro T, Saku K. Left ventricular pseudoaneurysm following acute myocardial infarction. Intern Med. 2006;45(21):1221-3.
Matsuo Y, Miura SI, Kawamura A, Uehara Y, Rye KA, Saku K.. Newly developed reconstituted high-density lipoprotein containing sphingosine-1-phosphate induces endothelial tube formation. Atherosclerosis. 2006 Nov 20.
Kumagai K, Nakashima H, Tojo H, Yasuda T, Noguchi H, Matsumoto N, Ogawa M, Saku K. Pilsicainide for atrial fibrillation. Drugs. 2006;66(16):2067-73. Review.
Kiya Y, Miura S, Zhang B, Urata H, Saku K. Effect of levothyroxine on total lipid profiles as assessed by analytical capillary isotachophoresis in a patient with hypothyroidism. Endocr J. 2006;53(6):865-8.
Iwata A, Miura S, Shirai K, Kawamura A, Tomita S, Matsuo Y, Zhang B, Nishikawa H, Kumagai K, Matsuo K, Saku K.. Lower level of low-density lipoprotein cholesterol by statin prevents progression of coronary restenosis after successful stenting in acute myocardial infarction. Intern Med. 2006;45(15):885-90.
Mitsutake R, Niimura H, Miura S, Zhang B, Iwata A, Nishikawa H, Kawamura A, Kumagai K, Shirai K, Matsunaga A, Saku K.. Clinical significance of the coronary calcification score by multidetector row computed tomography for the evaluation of coronary stenosis in Japanese patients. Circ J. 2006;70(9):1122-7.
Kamochi H, Yamanouchi Y, Saku K.. Effects of angiotensin converting enzyme inhibitor and angiotensin II receptor blocker on ventricular defibrillation threshold. PacingClin Electrophysiol. 2006 29(7):747-52.
Shirai K, Saku K. Treatment strategy for patients with acute myocardial infarction.Intern Med. 2006;45(13):807-8.
Tanigawa H, Miura S, Matsuo Y, Fujino M, Sawamura T, Saku K. Dominant-negative lox-1 blocks homodimerization of wild-type lox-1-induced cell proliferation through extracellular signal regulated kinase 1/2 activation. Hypertension. 2006;48(2):294-300.
Zhang B, Katafuchi R, Arishima H, Matsunaga A, Rye KA, Saku K.. Effects of atorvastatin and apoA-I/phosphatidylcholine discs on triglyceride-rich lipoprotein subfractions as characterized by capillary isotachophoresis. Clin Chim Acta. 2006;373(1-2):55-61.
Imaizumi S, Miura S, Nishikawa H, Iwata A, Zhang B, Kawamura A, Tsuchiya Y, Kumagai K, Matsuo K, Saku K. Angiotensin II type 1 receptor blockers do not promote coronary collateral circulation in patients with coronary artery disease. Hypertens Res. 2006;29(3):135-41.
Uehara Y, Miura S, von Eckardstein A, Abe S, Fujii A, Matsuo Y, Rust S, Lorkowski S, Assmann G, Yamada T, Saku K Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsive element. Atherosclerosis. 2007;191(1):11-21.
Miura S, Fujino M, Hanzawa H, Kiya Y, Imaizumi S, Matsuo Y, Tomita S, Uehara Y, Karnik SS, Yanagisawa H, Koike H, Komuro I, Saku. Molecular mechanism underlying inverse agonist of angiotensin II type 1 receptor. J Biol Chem. 2006;281(28):19288-95.
Zhang B, Bottcher A, Imaizumi S, Noda K, Schmitz G, Saku K. Relation between charge-based apolipoprotein B-containing lipoprotein subfractions and remnant-like particle cholesterol levels. Atherosclerosis. 2007;191(1):153-61.
Iwata A, Miura S, Nishikawa H, Kawamura A, Matsuo Y, Sako H, Kumagai K, Matsuo K, Saku K Significance of combined angiotensin II receptor blocker and carvedilol therapy in patients with congestive heart failure and arginine variant. J Cardiol. 2006;47(1):1-7.
Tanigawa H, Miura S, Zhang B, Uehara Y, Matsuo Y, Fujino M, Sawamura T, Saku K. Low-density lipoprotein oxidized to various degrees activates ERK1/2 through Lox-1. Atherosclerosis. 2006;188(2):245-50.
Kumagai K, Noguchi H, Ogawa M, Nakashima H, Zhang B, Miura S, Saku K. New aproach to pulmonary vein isolation for atrial fibrillation using a multielectrode basket catheter. Circ J. 2006;70(1):88-93.
Tsuji E, Tsuji Y, Fujiwara T, Ogata S, Tsukamoto K, Saku K.Splicing variant of Cdc42 interacting protein-4 disrupts beta-catenin-mediated cell-cell adhesion: expression and function in renal cell carcinoma. Biochem Biophys Res Commun. 2006;339(4):1083-8.
Zhang B, Miura S, Fan P, Kumagai K, Takeuchi K, Uehara Y, McMahon M, Rye KA, Saku K. ApoA-I/phosphatidylcholine discs remodels fast-migrating HDL into slow-migrating HDL as characterized by capillary isotachophoresis. Atherosclerosis. 2006;18:95-101.
Fujino M, Miura S, Matsuo Y, Tanigawa H, Kawamura A, Saku K. Pitavastatin-induced downregulation of CCR2 and CCR5 in monocytes is associated with the arrest of cell-cycle in S phase. Atherosclerosis. 2006;187(2):301-8.
Zhang B, Maeda N, Okada K, Tatsukawa M, Sawayama Y, Matsunaga A, Kumagai K, Miura S, Nagao T, Hayashi J, Saku K Association between fast-migrating low-density lipoprotein subfraction as characterized by capillary isotachophoresis and intima-media thickness of carotid artery. Atherosclerosis. 2006;187(1):205-12.
Song J, Ogawa M, Tan AY, Chen PS, Lin SF.Heart Rate Variability and Autonomic Nerve Activities in Ambulatory Dogs.Conf Proc IEEE Eng Med Biol Soc.2006.1:1780-3
Hwang GS, Hayashi H, Tang L, Ogawa M, Hernandez H, Tan AY, Li H, Karagueuzian HS, Weiss JN, Lin SF, Chen PS.Intracellular calcium and vulnerability to fibrillation and defibrillation in Langendorff-perfused rabbit ventricles.Circulation.2006.114(24):2595-603
2005年
Nishikawa H, Miura S, Shimomura H, Kawamura A, Tsujita K, Shirai K, Matsuo K, Arai H, Saku K. Effect of statin on restenosis after radius stent implantation in patients with acute coronary syndrome. J Atheroscler Thromb. 2005;12:302-6.
Zhang B, Shono N, Fan P, Ando S, Xu H, Jimi S, Miura S, Kumagai K, Win KM, Matsunaga A, Iwasaski H, Saku K. Histochemical characteristics of soleus muscle in angiotensin-converting enzyme gene knockout mice. Hypertens Res. 2005;28:681-8.
Takeuchi K, Ideishi M, Tashiro T, Morishige N, Yamada T, Saku K, Urata H. Higher small arterial elasticity in hypertensive patients treated with angiotensin II receptor blockers. Hypertens Res. 2005;28:639-44.
Tanigawa H, Miura S, Zhang B, Uehara Y, Matsuo Y, Fujino M, Sawamura T, Saku K. Low-density lipoprotein oxidized to various degrees activates ERK1/2 through Lox-1.
Atherosclerosis. 2005 (in press)
Noda K, Zhang B, Uehara Y, Miura S, Matsunaga A, Saku K. Potent capillary isotachophoresis (cITP) for analyzing a marker of coronary heart disease risk and electronegative low-density lipoprotein (LDL) in small dense LDL fraction. Circ J. 2005;69:1568-70.
Tojo H, Kumagai K, Noguchi H, Ogawa M, Yasuda T, Nakashima H, Zhang B, Miura S, Saku K. Hybrid therapy with pilsicainide and pulmonary vein isolation for atrial fibrillation. Circ J. 2005;69:1503-7.
Kumagai K, Ogawa M, Noguchi H, Nakashima H, Zhang B, Miura S, Saku K. Comparison of 2 mapping strategies for pulmonary vein isolation. Circ J. 2005;69:1496-502.
Zhang B, Miura S, Fan P, Kumagai K, Takeuchi K, Uehara Y, McMahon M, Rye KA, Saku K. ApoA-I/phosphatidylcholine discs remodels fast-migrating HDL into slow-migrating HDL as characterized by capillary isotachophoresis. Atherosclerosis. 2005 (in press)
Fujino M, Miura S, Matsuo Y, Tanigawa H, Kawamura A, Saku K. Pitavastatin-induced downregulation of CCR2 and CCR5 in monocytes is associated with the arrest of cell-cycle in S phase. Atherosclerosis. 2005 (in press)
Zhang B, Maeda N, Okada K, Tatsukawa M, Sawayama Y, Matsunaga A, Kumagai K, Miura S, Nagao T, Hayashi J, Saku K. Association between fast-migrating low-density lipoprotein subfraction as characterized by capillary isotachophoresis and intima-media thickness of carotid artery. Atherosclerosis. 2005 (in press)
Miura S, Matsuo Y, Kawamura A, Saku K. JTT-705 blocks cell proliferation and angiogenesis through p38 kinase/p27(kip1) and Ras/p21(waf1) pathways. Atherosclerosis. 2005;182:267-75.
Zhang B, Fan P, Shimoji E, Itabe H, Miura SI, Uehara Y, Matsunaga A, Saku K. Modulating effects of cholesterol feeding and simvastatin treatment on platelet-activating factor acetylhydrolase activity and lysophosphatidylcholine concentration. Atherosclerosis. (in press)
Zhang B, Kaneshi T, Ohta T, Saku K. Relation between insulin resistance and fast-migrating LDL subfraction as characterized by capillary isotachophoresis. J Lipid Res. 2005;46:2265-77
Miura S, Fujino M, Matsuo Y, Tanigawa H, Saku K. Nifedipine-induced vascular endothelial growth factor secretion from coronary smooth muscle cells promotes endothelial tube formation via the kinase insert domain-containing receptor/fetal liver kinase-1/NO pathway. Hypertens Res. 2005;28:147-53.
Fujino M, Miura S, Tanigawa H, Matsuo Y, Saku K Counteracting effects of high density lipoprotein-cholesterol subfractions on statin-induced growth arrest. Cardiovasc Drugs Ther. 2005;19:113-8.
Ogawa M, Kumagai K, Yamanouchi Y, Saku K. Spontaneous onset of ventricular fibrillation in Brugada syndrome with J wave and ST-segment elevation in the inferior leads. Heart Rhythm. 2005;2:97-9.
Nishikawa H, Miura S, Shimomura H, Tsujita K, Okamura K, Zhang B, Iwata A, Shirai K, Matsuo K, Arai H, Saku K. Combined treatment with statin and angiotensin-receptor blocker after stenting as a useful strategy for prevention of coronary restenosis. J Cardiol. 2005;45:107-13.
Miura S, Karnik SS, Saku K. Constitutively active homo-oligomeric angiotensin II type 2 receptor induces cell signaling independent of receptor conformation and ligand stimulation. J Biol Chem. 2005;280:18237-44.
Miura S, Emoto M, Matsuo Y, Kawarabayashi T, Saku K. The combination of Jun N-terminal kinase inhibitor and TNP-470 blocks carcinosarcoma-induced endothelial cell tube formation in a synergistic manner. Cancer Lett. 2005;220:49-55.
Zhang B, Noda K, Matsunaga A, Kumagai K, Saku K. A comparative crossover study of the effects of fluvastatin and pravastatin (FP-COS) on circulating autoantibodies to oxidized LDL in patients with hypercholesterolemia. J Atheroscler Thromb. 2005;12:41-7.
Noguchi H, Kumagai K, Yasuda T, Ogawa M, Tojo H, Saku K. Conduction recovery after pulmonary vein isolation for atrial fibrillation. Circ J. 2005;69:65-8.
Zhang B, Tomura H, Kuwabara A, Kimura T, Miura S, Noda K, Okajima F, Saku K. Correlation of high density lipoprotein (HDL)-associated sphingosine 1-phosphate with serum levels of HDL-cholesterol and apolipoproteins. Atherosclerosis. 2005;178:199-205.
2004年
Kawamura A, Miura S, Murayama T, Iwata A, Zhang B, Nishikawa H, Tsuchiya Y, Matsuo K, Tsuji E, Saku K. Increased Expression of Monocyte CD11a and Intracellular Adhesion Molecule-1 in Patients With Initial Atherosclerotic Coronary Stenosis. Circ J. 68:6-10. 2004
Miura S, Emoto M, Matsuo Y, Kawarabayashi T, Saku K. Carcinosarcoma-induced endothelial cells tube formation through KDR/Flk-1 is blocked by TNP-470. Cancer Lett. 203:45-50. 2004
Nishikawa H,Miura S,Zhang B,Shimomura H,Arai H,Tsuchiya Y,Matsuo K,Saku K. Statins Induce the Regression of Left Ventricular Mass in Patients With Angina. Circ J. 68:121-125. 2004
Fukuma G, Oguni H,Shirasaka Y,Watanabe K,Miyajima T,Yasumoto S,Ohfu M,Inoue T,Watanachai A,Kira R,Matsuo M,Muranaka H,Sofue F,Zhang B,Kaneko S,Mitsudome A,Hirose S. Mutations of Neuronal Voltage-gated Na+Channel α1 Subunit Gene SCN1A in Core Severe Myoclonic Epilepsy in Infancy(SMEI)and in Borderline SMEI(SMEB). Epilepsia. 45:140-148. 2004
Ikewaki K,Matsunaga A,Han H,Watanabe H,Endo A,Tohyama J,Kuno M,Mogi J,Sugimoto K,Tada N,Sasaki J,Mochizuki S. A novel two nucleotide deletion in the apolipoprotein A-1 gene,apo A-1 Shinbashi,associated with high density lipoprotein deficiency,corneal opacities,planar xanthomas,and premature coronary artery disease. Atherosclerosis. 172:39-45.2004
Zhang B,Bai H,Liu R,Kumagai K,Itabe H,Takano T,Saku K. Serum high-density lipoprotein-cholesterol levels modify the association between plasma levels of oxidatively modified low-density lipoprotein and coronary artery disease in men. Metabolism. 53:423-429. 2004
Shimoji E, Zhang B, Fan P, Saku K. Inhibition of cholesteryl ester transfer protein increases serum apolipoprotein(apo) A-II levels by increasing the synthesis of apo A-Ⅰin rabbits. Atherosclerosis. 172:247-257. 2004
Noguchi H, Kumagai K, Tohjoh H, Yasuda T, Saku K. Effect of Bachmann's bundle pacing on atrial fibrillation:electrophysiologic assessment. Clin Cardiol. 27:50-53. 2004
Zhang B, Tanaka H, Saku K. Simple and rapid detection of uncoupling protein-2 -866G/A polymorphism by mutagenically separated polymerase chain reaction. Clinica Chimica Acta. 344:205-210. 2004
Washio M, Hayashi R, Fukuoka Heart Study Group(include Shirai K, Nii T, Ideishi M, Arakawa K, Handa K, Takada K, Kawano T, Doi Y, Mori T, Oda S, Hiroki T, Miyawaki R, Fujino M, Fukuda K, Kanaya H, Kato Y, Ohga M, Sata T, Tashiro T). Past History of Obesity (Overweight by WHO Criteria) Is Associated with an Increased Risk of Nonfatal Acute Myocardial Infaction -A Case-Control Study in Japan-. Circ J. 68:41-46. 2004
Lansky A J, Mehran R, Dangas G, Cristea E, Shirai K, Costa R, Costantini C O, Tsuchiya Y, Carlier S, Mintz G S, Cottin Y, Stone G W, Moses J W, Leon M B. Comparison of Differences in Outcome after Percutaneous Coronary Intervention in Men-vs-Women Less Than 40 Years of Age. Am J Cardiol. 93:916-919. 2004
Shirai K, Lansky A J, Mehran R, Dangas G, Costantini C O, Fahy M, Slack S, Mintz G S, Stone G W, Leon M B. Minimlly Invasive Coronary Artery Bypass Grafting versus Stenting for Patients with Proximal Left Anterior Descending Coronary Artery Disease. Am J Cardiol. 93:959-962. 2004
Kawamura A, Miura S, Murayama T, Iwata A, Nishikawa H, Matsuo Y, Tsuchiya Y, Matsuo K, Tsuji E, Saku K. Changes in the Expression of Leukocyte Adhesion Molecules Throughout the Acute Phase of Myocardial Infarction. Journal of Atherosclerosis and Thrombosis. 11:29-34. 2004
Miida T, Zhang B, Obayashi K, Seino U, Zhu Y, Ito T, Nakamura Y, Okada M, Saku K. T13M mutation of lecithin-cholesterol acyltransferase gene causes fish-eye disease. Clinica Chimica Acta. 343:201-8. 2004
Shirai K, Saku K. Percutaneous Coronary Intervention for Small Caliber Proximal Coronary Artery Vessels : To Stent or Not to Stent? Med Bull Fukuoka Univ. 31:67-71. 2004
Kawano Y, Nagamine K, Arikado S, Nagashima F, Aridome K, Nishino T, Harasawa I, Hamada T, Matsuki H, Hirose N, Ogawa M, Kimura M. Effusive Constrictive Tuberculous Pericarditis -Report of a Case. Med. Bull. Fukuoka Univ. 31:117-123. 2004
Kumagai K, Ogawa M, Noguchi H, Yasuda T, Nakashima H, Saku K. Electrophysiologic Properties of Pulmonary Veins Assessed Using a Multielectrode Basket Catheter. Journal of the American College of Cardiology. 43:2281-9. 2004
Miura s, Matsuo Y, Saku K. Simvastatin suppresses coronary artery endothelial tube formation by disrupting Ras/Raf/ERK signaling. Atherosclerosis. 175:235-243. 2004
Niimura H, Matsunaga A, Kumagai K, Ohwaki K, Ogawa M, Noguchi H, Yonemura K, Saku K.Genetic Analysis of Brugada Syndrome in Western Japan-Two Novel Mutations-. Circ J. 68(8):740-746. 2004
Yasuda T, Kumagai K, Ogawa M, Noguchi H, Tojo H, Matsumoto N, Saku K. Predictors of Successful Catheter Ablation for Atrial Fibrillation Using the Pulmonary Vein Isolation Technique. J Cardiol 44(2):53-58. 2004
FanP, ZhangB, KurokiS, SakuK. Pitavastatin, a Potent Hydroxymethylglutaryl Coenzyme a Reductase Inhibitor, Increases Cholesterol 7a-Hydroxylase Gene Expression in HepG2 Cells. Circ J 68:1061-1066. 2004.11
Ogawa M, Miyoshi K, Morito N, Kodama S, Yahiro E, Fujimi K, Ohta T, Mihara H, Yamanouchi Y, Urata H, Hiroki T, Saku K. Successful catheter ablation of ventricular tachycardia originating from the idiopathic saccular apical left ventricular aneurysm. Int J Cardiol. 93(2-3):343-46. 2004
Morito N, Ogawa M, Matsuo S, Mihara H, Miyoshi K, Yahiro E, Fujimi K, Ohta T, Kodama S, Yamanouchi Y, Urata H, Hiroki T, Saku K. Atrial septal defect in apical hypertrophic cardiomyopathy associated with coronary spasm. Int J Cardiol. 93:339-342. 2004
Okura Y, Hayashi K, Shingu T, Kajiyama G, Nakashima Y, Saku K. Diagnostic evaluation of acute pancreatitis in two patients with hypertriglyceridemia. World Journal of Gastroenterology. 10:3691-3695. 2004
Ogawa M, Kumagai K, Yamaouchi Y,S aku K. Spontaneous onset of ventricular fibrillation in Brugada syndrome with J wave and ST-segment elevation in the inferior leads. Heart Rhythm Society. 97-99. 2004
Zhang B, Fan P, Shimoji E, Huali Xu, Takeuchi K, Bian C, Saku K. Inhibition of Cholesteryl Ester Transfer Protein Activity by JTT-705 Increases Apolipoprotein E-Containing High-Density Lipoprotein and Favorably Affects the Function and Enzyme Composition of High-Density Lipoprotein in Rabbits. Arterioscler Thromb Vasc Biol. 1910-1915. 2004
Kumagai K,Tojo H, Noguchi H, Yasuda T, Ogawa M, Nakashima H, Zhang B, Saku K. Effects of the Na+Channel Blocker Pilsicainide on the Electrophysiologic Properties of Pulmonary Veins in Patients with Atrial Fibrillation. J Cardiovasc Electrophysiol. 15:1396-1401. 2004
Okura Y, Takao M, Zhang B, Nakashima H, Saku K. Cardiovascular Risk Factor Profiles and Endothelial Function in Coronary Artery Disease Patients Treated with Statins. Hypertens Res. 27:723-729. 2004
Miura S, Zhang B, Matsuo Y, Saku K ,Karnik SS. Activation of Extracellular Signal-Activated Kinaseby Angiotensin II-Induced Gq-Independent Epidermal Growth Factor Receptor Transactivation. Hypertens Res. 27:765-770.2004
Miura S, Yamaguchi Y, Urata H, Himeshima Y, Otsuka N, Tomita S, Yamatsu K, Nishida S, Saku K. Efficacy of a Multicomponent Program(Patient-Centered Assessment and Counseling for Exercise plus Nutrition [PACE+Japan])for Lifestyle Modification in Patients with Essential Hypertension. Hypertens Res. 27:859-964.2004
Kumagai K, Nakashima H, Saku K. The HMG-CoA reductase inhibitor atorvaststin prevents atrial fibrillation by inhibiting inflammation in a canine sterile pericarditis model. Cardiovascular Research. 62:105-111. 2004
Kumagai K, Ogawa M, Noguchi H, Yasuda T, Nakashima H, Saku K. Elwctrophysiologic Properties of Pulmonary Veins Assessed Using a Muultielectrode Basket Catheter. Journal of the Americann College of Cardiology. 43:2281-2289. 2004
Miura S, Fujino M, Matsuo Y, Tanigawa H, Saku K. Nifedipine-Induced Vascular Endothelial Growth Factor Secretion from Coronary Smoot Muscle Cells Promotes Endothelial Tube Formation via the Kinase Insert Domain-Containing Receptor/Fetal Kinase -1/NO Pathway. Hypertens Res. 28:147-153. 2004
2003年
Hoshino F,Urata H,Inoue Y,Saito Y,Yahiro E,Ideishi M, Arakawa K,Saku K. Chymase Inhibitor Improves Survival in Hamsters with Myocardial Infarction. Journal of Cardiovascular Pharmacology. 41:S11-S18. 2003
Noda K, Takeuchi K, Tashiro T, Kimura M, Saku K. Impaired Bradykinin-mediated Vascular Function is Associated with Coronary Atherosclerosis in Radial and Internal Mammary Arteries from CABG Patients. Med. Bull. Fukuoka Univ. 30:17-28. 2003
Miura S, Matsuo Y, Saku K. Transactivation of KDR/Flk-1 by the B2 Receptor Induces Tube Formation in Human Coronary Endothelial Cells. Hypertension. 41:1118-1123. 2003
Yahiro E,Ideishi M,Wang X L,Urata H,Kumagai K,Arakawa K,Saku K. Reperfusion-Induced Arrhythmias are Suppressed by Inhibition of the Angiotensin II type 1 Receptor. Cardiology. 99:61-67. 2003
Miura S, Fujino M, Matsuo Y, Kawamura A, Tanigawa H, Nishikawa H, Saku K.High Density Lipoprotein-Induced Angiogenesis Requires the Activation of Ras/MAP Kinase in Human Coronary Artery Endothelial Cells. Arterioscler Thromb Vasc Biol. 23:802-808. 2003
Miura S, Nishikawa H, Zhang B, Matsuo Y, Kawamura A, Tsuchiya Y, Matsuo K, Saku K. Angiotensin-Converting Enzyme Inhibitor Promotes Coronary Collateral Circulation in Patients With Coronary Artery Disease. Circ J 67:535-538. 2003
Kumagai K, Nakashima H, Urata H, Gondo N, Arakawa K, Saku K. Effects of Angiotensin II Type1 Receptor Antagonist on Electrical and Structural Remodeling in Atrial Fibrillation. J American College of Cardiology. 41:2197-2204. 2003
Okura Y, Hayashi K, Shingu T, Kuga Y, Nomura S, Kajiyama G, Nakashima Y, Saku K. Angiotensin-converting enzyme insertion / deletion genotype is associated with the activities of plasma coagulation factor X and X independent of triglyceride metabolism. Coronary Artery Disease. 14:285-291. 2003
Zhang B, Sakai T, Noda K, Kiyonaga A, Tanaka H, Shindo M, Saku K. Multivariate Analysis of the Prognostic Determinants of the Depressor Response to Exercise Therapy in Patients With Essential Hypertension. Circ J 67:579-584. 2003
Miura S, Tanigawa H, Matsuo Y, Fujino M, Kawamura A, Saku K. Ras/Raf1-dependent signal in sphingosine-1-phosphate-induced tube formation in human coronary artery endothelial cells. Biochem Bioph Res Co. 306:924-929. 2003
Kumagai K, Nakashima H, Saku K. Elevated C-Reactive Protein and Maintenance of Atrial Fibrillation. Clinical Cardiac Pacing and Electrophysiology. 427-432. 2003
Zhang B, Noda K, Saku K. Effect of Atorvastatin on Total Lipid Profiles Assessed by Analytical Capillary Isotachophoresis. Cardiology. 99:211-213. 2003
Shirai K, Lansky A J, Mintz G S,Costantini C O, Cristea E, Fahy M, Vandertie L, Yeung A, Raizner A E, Waksman R, Leon M B. Feasibility and Efficacy of Tandem Positioning on Angiographic and Clinical Outcomes in the Intimal Hyperplasia Inhibition With Beta In-Stent Trial. Am J Cardiol 91:1113-1115. 2003
Costantini C O, Lansky A J, Mintz G S, Shirai K, Teirstein P S, Stone G, Vandertie L, Proctor B, Fahy M, Yeung A, Raizner A E, Waksman R, Leon M B. Implications of the Presence and Length of "Geographic Miss"on Restenosis and the Edge Phenomenon in the INHIBIT Trial. Am J Cardiol 91:1261-1265. 2003
Costantini C O, Lansky A J, Mintz G S, Shirai K, Dangas G, Mehran R, Fahy M, Stone G, Moses J, Leon M B . Intravascular Brachytherapy for Native Coronary Ostial In-Stent Restenotic Lesions. Journal of the American College of Cardiology. 41:1725-1731. 2003
Kumagai K, Nakashima H, Gondo N, Saku K. Antiarrhythmic Effects of JTV-519,a Novel Cardioprotective Drug,on Atrial Fibrillation/Flutter in a Canine Sterile Pericarditis Model. Journal of Cardiovascular Electrophysiology. 14:880-884. 2003
Takahashi Y,Iesaka Y,Takahashi A,Harada T,Mitsuhashi T, Shirota K,Kumagai K,Nuruki N,Shiraishi T,Nitta J,Ito H and The Ablation and Pacing Therapy Working Group. AV Nodal Ablation and Pacemaker Implantation Improves Hemodynamic Function in Atrial Fibrillation. Pacing and Clinical Electrophysiology. 26:1212-1217. 2003
Kawamura A, Miura S, Fujino M, Nishikawa H, Matsuo Y, Tanigawa H, Tomita S, Tsuchiya Y, Matsuo K, Saku K. CXCR3 Chemokine Receptor-Plasma IP10 Interaction in Patients With Coronary Artery Disease. Circulation Journal. 67:851-854. 2003
Koga T, Urata H, Inoue Y, Hoshino T, Okamoto T, Matsunaga A, Suzuki M, Miyazaki J, Ideishi M, Arakawa K, Saku K. Human Chymase Expression in a Mice Induces Mild Hypertension with Left Ventricular Hypertrophy. Hypertens Res. 26:759-768. 2003
Zhang B,Eto S,Fan P,Bian C,Shimoji E,Saito T,Saku K. Paraoxonase(Pon1)Q192R polymorphism and serum Pon1 activity in diabetic patients on maintenance hemodialysis. Clinical Nephrology. 60:257-265. 2003
Miura S, Saku K,Karnik S S. Molecular Analysis of the Structure and Function of the Angiotensin II Type1 Receptor. Hypertens Res. 26:937-943. 2003
Yamaguchi Y,Miura S,Urata H,Himeshima Y,Yamatsu K,Otsuka N,Nishida S,Saku K. The Effectiveness of a Multicomponent Program for Nutrition and Physical Activity Change in Clinical Setting:Short-term Effects of PACE+ Japan. International Journal of Sport and Health Science. 1(2)229-237. 2003
Sakata N, Takeuchi K, Noda K, Saku K, Tachikawa Y, Tashiro T, Nagai R, Horiuchi S. Calcification of the Medial Layer of the Internal Thoracic Artery in Diabetic Patients:Relevance of Glycoxidation. Journal of Vascular Research. 40:567-574. 2003
Yamaguchi Y, Miura S, Urata H, Himeshima Y, Yamatsu K, Otsuka N, Nishida S, Saku K. The Effectiveness of a Multicomponent Program for Nutrition and Physical Activity Change in Clinical Setting:Short-term Effects of PACE+Japan. International Journal of Sport and Health Science. 2:229-237. 2003
Costantini C O, Lansky A J, Mintz G S, Shirai K, Dangas G, Mehran R, Stone G, Leon M B. Usefulness of the angiographic pattern of in-stent restenosis in predicting the success of gamma vascular brachytherapy. Am J Cardiol. 92:1214-1217. 2003
Shirai K, Lansky A J, Mintz G S, Costantini C O, Fahy M, Mehran R, Dangas G, Moses J W, Stone G W, Leon M B. Comparison of the angiographic outcomes after beta versus gamma vascular brachytherapy for treatment of in-stent restenosis. Am J Cardiol. 92:1409-1413. 2003
Zhang B, Tanaka H, Shono N, Miura S, Kiyonaga A, Shindo M, Saku K. The I allele of the angiotensin -converting enzyme gene is associated with an increased percentage of slow-twitch type I fibers in human skeletal muscle. Clinical Genetics. 63:139-144. 2003
Miura S, Zhang J, Boros J, Karnik SS. TM2-TM7 interaction in coupling movement of transmembrane helices to activation of the angiotensin II type-1 receptor. J Biol Chem. 278: 3720-3725:2003.
2002年
OGAWA M, KUMAGAI K, GONDO N, MATSUMOTO N, SUYAMA K, SAKU K. Novel Electrophysiologic Parameter of Dispersion of Atrial Repolarization : Comparison of Different Atrial Pacing Methods. J Cardiovasc Electrophysiol. 13:110-117. 2002
Ogawa M, Hirose N, Ogimoto M, Matsuki H, Miki K, Kinoshita M, Koga A, Saku K. Chronic Benefical Effects of Type 1 Angiotensin II Receptor Antagonist in Patients with Chronic Hypoxemic Pulmonary Diseases. CARDIOLOGY. 97:111-112. 2002
Hideko Nakasima,Koichiro Kumagai,Hiroo Noguchi,HideakiTojo,Tomoo Yasuda and Keijiro Saku. Efficacy of Pulmonary Vein Isolation for Paroxysmal AtrialFibrillation. Med. Bull. Fukuoka Univ. 29:121-126. 2002
Nishikawa H, Miura S, Zhang B, Shimomura H, Arai H, Tsuchiya Y , Saku K. Pravastatin promotes coronary collateral circulation in patients with coronary artery disease. Coronary Artery Disease. 13:377-381. 2002
Miura S, Okamoto T, Via D P, Saku K. Transfer of Antisense Oligodeoxynucleotides Against Endothelin Receptors A and B Into Human Coronary Smooth Muscle Cells and Endothelial Cells by Apolipoprotein E Peptide-An in Vitro Study-.Circ J. 66:1054-1056. 2002
Aoki J, Taira A, Takanezawa Y, Kishi Y, Hama K, Kishimoto T, Mizuno K, Saku K, Taguchi R, Arai H. Serum Lysophosphatidic Acid Is Produced through Diverse Phospholipase Pathways. J Bio Chem. 277:48737-48744. 2002
Nomoto J, Oku K , Takao M, Tahara H, Inoue T, Handa K, Arakawa K, Saku K. Left Atrial Thrombus Formation in Patients with Nonvalvular Paroxysmal Atrial Fibrillation. Med.Bull.Fukuoka Univ. 29:187-194. 2002
Takase H,Sakiyama E,Noda K,Ono N,Saku K. The Administrative Management Division for Clinical Drug Trials(ACDT) at Fukuoka University Hospital. Med.Bull.Fukuoka Univ. 29:221-229. 2002
Nakashima H,Kumagai K,Tojo H,Yasuda T,Noguchi H,Matsumoto N, Saku K. Simultaneous catheter mapping of the pulmonary veins in focal atrial fibrillation:significance of rapid focal activation. Jpn Heart J.43:357-365. 2002
Nakashima H,Kumagai K,Noguchi H,Tojo H,Yasuda T,Saku K. Evaluation of the recurrence of atrial fibrillation after pulmonary venous ablation. J Cardiol. 40:87-94. 2002
Miura S, Tachibana K, Okamoto T, Saku K. In vitro transfer of antisense oligodeoxynucleotides into coronary endothelial cells by ultrasound. Biochem Biophys Res Commun. 298:587-590. 2002
Zhang B,Sakai T,Miura S,Kiyonaga A,Tanaka H,Shindo M,Saku K. Association of angiotensin -converting-enzyme gene polymorphism with the depressor response to mild exercise theraphy in patients with mild to moderate essential hypertension. Clinical Genetics. 62:328-333. 2002
Uehara Y,Urata H,Ideishi M,Arakawa K,Saku K. Chymase inhibition suppresses high-cholesterol diet-induced lipid accumulation in the hamster aorta. Cardiovascular Research. 55:870-876. 2002
Miura S, Karnik SS. Constitutive Activation of AngiotensinII Type-1 Receptor Althers the Orientation of Transmembrane Helix-2. J BiolChem. 277:24299-24305:2002.
2001年
Koichiro Kumagai, Hideaki Tojo, Hiroo Noguchi, Tomoo Yasuda, Hideki Tamari, Naomichi Matsumoto, Naoki Gondo, Hideko Nakashima and Keijiro Saku. Effects of Cavotricuspid Isthmus Catheter Ablation on Paroxysmal Atrial Fibrillation. Jpn Heart J. 42:79-89 2001
BO ZHANG, PING FAN, HIROAKI TANAKA and KEIJIRO SAKU. Angiotensin II type-1 receptor antagonisut, CS-866, reduces blood pressure without affecting glucose/insulin metabolism in cholesterol-fed rabbits. British Journal of Biomedical Science 58:217-225 .2001