福岡大学 医学部 心臓・血管内科学講座

実績紹介 Results

2017年

  • Miyamoto S, Yotsumoto F, Ueda T, Fukami T, Sanui A, Miyata K3, Nam S, Fukagawa S, Katsuta T, Maehara M, Kondo H, Miyahara D, Shirota K, Yoshizato 6, Kuroki M, Nishikawa H, Saku K, Tsuboi Y, Ishitsuka K, Takamatsu Y, Tamura K, Matsunaga A, Hachisuga T, Nishino S, Odawara T, Maeda K, Manabe S, Ishikawa T, Okuno Y13, Ohishi M, Hikita T, Mizushima H, Iwamoto R, Mekada E. BK-UM in patients with recurrent ovarian cancer or peritoneal cancer: a first-in-human phase-I study.BMC Cancer.2017.01.17(1):89
  • Norimatsu K*, Kuwano T*, Miura S,Shimizu T, Shiga Y, Suematsu Y, Miyase Y, Adachi S, Nakamura A, Imaizumi S, Iwata A, Nishikawa H, Uehara Y, Saku K.Significance of the percentage of cholesterol efflux capacity and total cholesterol efflux capacity in patients with or without coronary artery disease.Heart Vessels.2017.01.32(1):30-38
  • Shiga Y, Miura S, Motozato K, Yoshimine Y, Norimatsu K, Arimura T, Koyoshi R, Morii J, Kuwano T, Inoue K, Shirotani T, Fujisawa K, Matsunaga E, Saku K.Efficacy and Safety of Combination Therapy Consisting of Angiotensin II Type 1 Receptor Blocker, Calcium Channel Blocker and Hydrochlorothiazide in Patients With Hypertension.J Clin Med Res.2017.02.9(2):98-103
  • Ueda T, Noda K, Kiyomi, Yanase T, Saku K.Follow-up to the STYLIST study (Lifestyle Changes Through the Use of Delivered Meals and Dietary Counseling):the STYLIST EXTENSION study.福岡大学医学紀要.2017.0344(1):7-14
  • Komaki T, Miura S, Arimura T, Shiga Y, Morii J, Kuwano T, Imaizumi S, Kitajima K, Iwata A, Morito N, Yahiro E, Fujimi K, Matsunaga A, Saku K.The Change in Body Weight During Hospitalization Predicts Mortality in Patients With Acute Decompensated Heart Failure.J Clin Med Res.2017.03.9(3):200-206
  • Matsumoto N, Ogawa M, Morii J, Nagata Y, Imaizumi S, Matsunaga A, Saku K.Successful Catheter Ablation of Two Distinct Premature Ventricular Complexes Arising from Right Ventricular Outflow Tract Guided by EnSite NavX 3-D Mapping System with Multielectrode Basket Catheter.福岡大学医学紀要.2017.03.44(1):35-40
  • Gondo K, Ike A, Ogawa M, Shirai K, Sugihara M, Nishikawa H, Iwata A, Kawamura A, Mori K, Zhang B, Miura S, Yasunaga S, Saku K.Is Bare-metal Stent Still Useful for Improving Outcomes of Percutaneous Coronary Intervention?:From the FU-Registry.Journal of Cardiology.2017.04.69(4):652-659
  • Ishida T, Miura S, Fujimi K, Futami M, Ueda Y, Ueda T, Arimura T, Koyoshi R, Shiga Y, Kitajima K, Saku K.Significance of Cardiac Rehabilitation on Visit-to-Visit Variability of Blood Pressure in Patients With Cardiovascular Disease in a 12-Month Follow-Up.J Clin Med Res.2017.04.9(4):345-352
  • Adachi S, Miura S, Shiga Y, Arimura T, Morii J, Kuwano T, Kitajima K, Iwata A, Morito N, Fujimi K, Yahiro E, Nishikawa H, Saku K.Effects of Tolvaptan With or Without the Pre-Administration of Renin-Angiotensin System Blockers in Hospitalized Patients With Acute Decompensated Heart Failure.Int Heart J.2017.05.58(3):385-392
  • Shiga Y, Miura S, Motozato K, Norimatsu K, Yano M, Hitaka Y, Adachi S, Kuwano T, Inoue K, Inoue A, Fujisawa K, Shirotani T, Kusumoto T, Ideishi M, Saku K.Comparison of Efficacy and Safety of Azilsartan and Olmesartan in Patients With Essential Hypertension.Int Heart J.2017.05.58(3):416-421
  • Kato Y, Iwata A, Nakamura M, Miura S, Saku K.In-Stent Restenosis due to Stent Recoil After Third-Generation Drug-Eluting Stent Implantation.J Clin Med Res.2017.06.9(6):534-538
  • Arinaga T, Komaki T, Miura S, Futami M, Morii J, Sugihara M, Saku K. A rare case of eosinophilic granulomatosis with polyangiitis complicated with progressive pericardial effusion. Journal of Cardiology Cases. 2017.05.15(5):163-166
  • Komaki T, Miura S, Gondo K, Nakamura A, Ike A, Matsunaga A, Saku K. A rare case of acute myocardial infarction with a non-specific symptom in a young female with systemic lupus erythematosus. Journal of Cardiology Cases. 2017.08.16(2):56-61
  • Komaki T, Urata H, Mori K, Iwashita A, Ikeda K, Haraoka S. A Rare Case of Biphasic Malignant Peritoneal Mesothelioma with Refractory Ascites. Internal Medicine. 2017. 56(7):861-864

2016年

  • Tei C, Imamura T, Kinugawa K, Inoue T, Masuyama T, Inoue H, Noike H, Muramatsu T, Takeishi Y, Saku K, Harada K, Daida H, Kobayashi Y, Hagiwara N, Nagayama M, Momomura S, Yonezawa K, Ito H, Gojo S, Akaishi M, Miyata M, Ohishi M. Waon Therapy for Managing Chronic Heart FailureCirculation. Journal.2016.80(4):827-34
  • Kumagai N, Ogawa M, Zhang B, Koyoshi R, Morii J, Yasuda T, Matsumoto N, Matsuo K, Saku K.Paradoxical nocturnal elevation of sympathetic tone and spontaneous ventricular fibrillation in Brugada syndrome. Journal of Cardiology.2016.67(3):229-235
  • Arimura T, Miura S, Morito N, Shiga Y, Kitajima K, Morii J, Iwata A, Fujimi K, Yahiro E, Saku K.Recent Patient Characteristics and Medications at Admission and Discharge in Hospitalized Patients With Heart Failure. Journal of Clinical Medicine Research.2016.8(2):97-104
  • Takata K, Imaizumi S, Kawachi E, Yahiro E, Suematsu Y, Shimizu T, Abe S, Matsuo Y, Nakajima K, Yasuno T, Jimi S, Zhang B, Uehara Y, Miura S, Saku K.The ApoA-I mimetic peptide FAMP promotes recovery from hindlimb ischemia through a nitric oxide (NO)-related pathway.International Journal of Cardiology.2016.15(207):317-325
  • Goto M, Miura S, Yamamoto T, Fukuda Y, Kuwano T, Kimura I, Sanui A, Miyamoto S, Saku K.Anticoagulant Therapy in a Pregnant Woman with May-Thurner Syndrome. Internal Medicine.2016.55(1):59-62
  • Suematsu Y, Miura S, Takata K, Shimizu T, Kuwano T, Imaizumi S, Matsuo Y, Yahiro E, Uehara Y, Saku K.A novel inducible cholesterol efflux peptide, FAMP, protects against myocardial ischemia reperfusion injury through a nitric oxide pathway. International Journal of Cardiology.2016.202:810-816
  • Norimatsu K, Miura S, Suematsu Y, Shiga Y, Miyase Y, Nakamura A, Zhang B, Saku K.Association between pentraxin 3 levels and aortic valve calcification.J Cardiol.2016.68:76-82
  • Miyase Y, Miura S, Shiga Y, Yano M, Suematsu Y, Adachi S, Norimatsu K, Nakamura A, Saku K.Association between the severity of coronary artery stenosis and the combination of the difference in blood pressure between arms and brachial-ankle pulse wave velocity.Clin Exp Hypertens. 2016. 38:81-88
  • Imaizumi S, Miura S, Takata K, Takamiya Y, Kuwano T, Sugihara M, Ike A, Iwata A, Nishikawa H, Saku K.Association between cholesterol efflux capacity and coronary restenosis after successful stent implantation.Heart Vessels.2016.31:1257-1265
  • Motozato K, Miura S, Shiga Y, Kusumoto T, Adachi S, Inoue T, Fujisawa K, Saku K.Efficacy and safety of two single-pill fixed-dose combinations of angiotensin II receptor blockers/calcium channel blockers in hypertensive patients (EXAMINER study).Clin Exp Hypertens. 2016. 38(1):45-50
  • Suematsu Y, Miura S, Zhang B, Uehara Y, Ogawa M, Yonemoto N, Nonogi H, Nagao K, Kimura T, Saku K.Association between dental caries and out-of-hospital cardiac arrests of cardiac origin in Japan.J Cardiol.2016.67:384-391
  • Yamamoto T, Miura S, Suematsu Y, Kuwano T, Sugihara M, Ike A, Iwata A, Nishikawa H, Saku K.A relative difference in systolic blood pressure between arms by synchronal measurement and conventional cardiovascular risk factors are associated with the severity of coronary atherosclerosis.Heart Vessels. 2016. 31:863-870
  • Hitaka Y*, Ogawa M*, Zhang B, Goto S, Nagata Y, Morii J, Imaizumi S, Yasuda T, Matsumoto N, Matsunaga A, Saku K.Circadian variations in laboratory measurements of coagulation assays after administration of rivaroxaban or warfarin in patients with nonvalvular atrial fibrillation.Journal of Cardiology. 2016. 68(6):529-535
  • Ikenaga M, Higaki Y, Saku K, Uehara Y.High-Density Lipoprotein Mimetics: a Therapeutic Tool for Atherosclerotic Diseases.J Atheroscler Thromb.2016.23(4):385-94
  • Suematsu Y, Miura S, Goto M, Matsuo Y, Arimura T, Kuwano T, Imaizumi S, Iwata A, Yahiro E, Saku K.LCZ696, an angiotensin receptor-neprilysin inhibitor, improves cardiac function with the attenuation of fibrosis in heart failure with reduced ejection fraction in streptozotocin-induced diabetic mice.European Journal of Heart Failure. 2016.01.07. 18(4):386-393
  • Ng VG, Mori K, Costa RA, Kish M, Mehran R, Urata H, Saku K, Stone GW, Lansky AJ.Impact of gender on infarct size, ST-segment resolution, myocardial blush and clinical outcomes after primary stenting for acute myocardial infarction: Substudy from the EMERALD trial.Int J Cardiol. 2016.03.15. 207:269-276
  • Nagao K, Nonogi H, Yonemoto N, Gaieski DF, Ito N, Takayama M, Shirai S, Furuya S, Tani S, Kimura T, Saku K; Japanese Circulation Society With Resuscitation Science Study (JCS-ReSS) Group*. Duration of Prehospital Resuscitation Efforts After Out-of-Hospital Cardiac Arrest. Circulation. 2016.04.05. 133(14):1386-1396
  • Hitaka Y, Miura S, Koyoshi R, Suematsu Y, Miyase Y, Norimatsu K, Adachi S, Shiga Y, Morito N, Nishikawa H, Saku K.Associations between parameters of flow-mediated vasodilatation obtained by continuous measurement approaches and the presence of coronary artery disease and the severity of coronary atherosclerosis.Clin Exp Hypertens. 2016.06.30. 38(5):443-450
  • Yano M, Miura S, Shiga Y, Miyase Y, Suematsu Y, Norimatsu K, Nakamura A, Adachi S, Nishikawa H, Saku K.Association between smoking habits and severity of coronary stenosis as assessed by coronary computed tomography angiography.Heart Vessels. 2016.07. 31(7):1061-1068
  • Ueda T, Miura S, Suematsu Y, Shiga Y, Kuwano T, Sugihara M, Ike A, Iwata A, Nishikawa H, Fujimi K, Saku K.Association of Arterial Pressure Volume Index With the Presence of Significantly Stenosed Coronary Vessels.J Clin Med Res.2016.08. 8(8):598-604
  • Adachi S, Miura S, Shiga Y, Arimura T, Kuwano T, Kitajima K, Ike A, Sugihara M, Iwata A, Nishikawa H, Morito N, Saku K.Depressor and Anti-Inflammatory Effects of Angiotensin II Receptor Blockers in Metabolic and/or Hypertensive Patients With Coronary Artery Disease: A Randomized, Prospective Study (DIAMOND Study).J Clin Med Res. 2016.08.30. 8(10):743-748
  • Ueda T, Miura S, Fujimi K, Ishida T, Matsuda T, Fujita M, Ura Y, Kaino K, Sakamoto M, Horita T, Arimura T, Shiga Y, Kuwano T, Kitajima K, Saku K.Assessment of various parameters using simple non-invasive tests in patients with cardiovascular diseases with or without cardiac rehabilitation. IJC Heart & Vasculature. 2016.09. 12:63-67
  • Idemoto Y, Miura S, Norimatsu K, Suematsu Y, Hitaka Y, Shiga Y, Morii J, Imaizumi S, Kuwano T, Iwata A, Zhang B, Ogawa M, Saku K.Evaluation of the antithrombotic abilities of non-vitamin K antagonist oral anticoagulants using the Total Thrombus-formation Analysis System℗ . Heart Vessels. 2016.1.21. 32:309-316
  • Goto M, Miura S, Suematsu Y, Idemoto Y, Takata K, Imaizumi S, Uehara Y, Saku K.Rivaroxaban, a factor Xa inhibitor, induces the secondary prevention of cardiovascular events after myocardial ischemia reperfusion injury in mice.Int J Cardiol. 2016.10.01. 220:602-607
  • Kuwano T, Miura S, Norimatsu K, Arimura T, Shiga Y, Tomita S, Nakayama A, Matsuo Y, Imaizumi S, Saku. KAdvanced glycation of high-density lipoprotein and the functionality of aldosterone release in type 2 diabetes.Hypertens Res.2016.10.13.40(3):271-276
  • Miura S, Suematsu Y, Matsuo Y, Tomita S, Nakayama A, Goto M, Arimura T, Kuwano T, Yahiro E, Saku K.The angiotensin II type 1 receptor-neprilysin inhibitor LCZ696 blocked aldosterone synthesis in a human adrenocortical cell line. Hypertens Res. 2016.11. 39(11):758-763
  • Sai K, Kajinami K, Akao H, Iwadare M, Sato-Ishida R, Kawai Y, Takeda K, Tanimoto T, Yamano T, Akasaka T, Ishida T, Hirata K, Saku K, Yagi S, Soeki T, Sata M, Ueno M, Miyazaki S, Shiraki A, Oyama J, Node K, Sugamura K, Ogawa H, Kurose K, Maekawa K, Matsuzawa Y, Imatoh T, Hasegawa R; Japanese Pharmacogenomics Data Science Consortium, Saito Y. A possible role for HLA-DRB1*04:06 in statin-related myopathy in Japanese patients.Drug Metabolism And Pharmacokinetics. 2016.12. 31:467-470
  • Motozato K, Miura S, Shiga Y, Kusumoto T, Saku K.Efficacy and Safety of a Single-Pill Fixed-Dose Combination of Azilsartan and Amlodipine.J Clin Med Res.2016.12.8(12):888-892
  • Sugihara H*, Idemoto Y, Kuwano T*, Nagata Y, Morii J, Sugihara M, Ogawa M, Miura S, Saku K.Evaluation of the Antithrombotic Effects of Rivaroxaban and Apixaban Using the Total Thrombus-Formation Analysis System®: In Vitro and Ex Vivo Studies. J Clin Med Res. 2016.12. ;8(12):899-907
  • Ikeda T, Atarashi H, Inoue H, Uchiyama S, Kitazono T, Yamashita T, Shimizu W, Kamouchi M, Kaikita K, Fukuda K, Origasa H, Sakuma I, Saku K, Okumura Y, Nakamura Y, Morimoto H, Matsumoto N, Tsuchida A, Ako J, Sugishita N, Shimizu S, Shimokawa H.Study Design and Baseline Characteristics of the EXPAND Study: Evaluation of Effectiveness and Safety of Xa Inhibitor, Rivaroxaban for the Prevention of Stroke and Systemic Embolism in a Nationwide Cohort of Japanese Patients Diagnosed as Non-Valvular Atrial Fibrillation. The Tohoku Journal of Experimental Medicine. 2016.12. 240(4):259-268
  • Hasegawa K, Kawachi E, Uehara Y, YoshidaT, Imaizumi S, Ogawa M, Miura S, Saku K.Improved 68Ga‐labeling method using ethanol addition: Application to the α‐helical peptide DOTA‐FAMP. Journal of Labelled Compounds and Radiopharmaceuticals. 2016.12.07. 60(1):55-61
  • Ishida T, Miura S, Fujimi K, Ueda T, Ueda Y, Matsuda T, Sakamoto M, Arimura T, Shiga Y, Kitajima K, Saku K.Visit-to-Visit Variability and Reduction in Blood Pressure After a 3-Month Cardiac Rehabilitation Program in Patients With Cardiovascular Disease.Int Heart J. 2016.9.28. 57(5):607-614

2015年

  • Shimizu T, Tanigawa H, Miura S, Kuwano T, Takata K, Suematsu Y, Imaizumi S, Yahiro E, Zhang B, Uehara Y, Saku K.Newly developed apolipoprotein A-I mimetic peptide promotes macrophage reverse cholesterol transport in vivo. International Journal of Cardiology.2015.1;192:82-8.
  • Yahiro E, Miura S, Suematsu Y, Matsuo Y, Arimura T, Kuwano T, Imaizumi S, Iwata A, Uehara Y, Saku K.Addition of a Nitric Oxide Donor to an Angiotensin II Type 1 Receptor Blocker May Cancel Its Blood Pressure-Lowering Effects. International Heart Journal.2015.56(6):656-660
  • Suematsu Y, Miura S, Takata K, Shimizu T, Kuwano T, Imaizumi S, Matsuo Y, Yahiro E, Uehara Y, Saku K.A novel inducible cholesterol efflux peptide, FAMP, protects against myocardial ischemia reperfusion injury through a nitric oxide pathwayInternational Journal of Cardiology.2015.202(2016):810816
  • Kumagai N, Ogawa M, Koyoshi R, Morii J, Yasuda T, Matsumoto N,Matsuo K, Zhang B, Saku K.Autonomic Imbalance and QT Dynamics in Idiopathic Ventricular Fibrillation 福岡大学医学紀要.2015.42(2):235-240
  • Okamura K, Urata H.Prevalence and Characteristic of Treatment-Resistant Hypertension among Hypertensive Japanese OutpatientsInternational Journal of Clinical Medicine.2015.623-634
  • Okamura K, Okuda T, Kumagai N, Mitsutake R, Urata H.Antihypertensive Effect and Safety of a Candesartan/Hydrochlorothiazide Combination in Patients with Uncontrolled HypertencionTherapeutic Research.2015.36(5):439-448
  • Nagata I, Ike A, Nishikawa H, Zhang B, Sugihara M, Mori K, Iwata A, Kawamura A, Shirai K, Uehara Y, Ogawa M, Miura S, Saku K. Associations between lipid profiles and MACE in hemodialysis patients with percutaneous coronary intervention: From the FU-Registry. Journal of Cardiology.2015.65:115-111
  • Norimatsu K, Miura S, Suematsu Y, Shigawa Y, Miyase Y, Nakamura A, Yamada M, MatsunagaA, Saku K. Associations between glycated albmin or hemoglobin A1c and the presence of coronary artery desease. Journal of Cardiology.2015.65(6):487-493
  • Ike A, Shirai K, Nishikawa H, Iwata A, Yahiro E, Sugihara M, Kawamura A, Uehara Y, Zhang B, Ogawa M, Mori K, Miura S, Saku K. Associations between different types of hypoglycemic agents and the clinical outcome of percutaneous coronary intervention in diabetic patients-From the FU-Registry. Journal of Cardiology.2015.65(5):390-396
  • Hitaka Y, Miura S, Koyoshi R, Shiga Y, Miyase Y, Norimatsu K, Nakamura A, Adachi S, Kuwano T, Sugihara M, Ike A, Nishikawa H, Saku K.Impact of the Absolute Difference in Diastolic Blood Pressure Between Arms in Patients With Coronary Artery Disease. J Clin Med Res20157(11):873-879
  • Devarajan S, Yahiro E, Uehara Y, Habe S, Nishiyama A, Miura S, Saku K, Urata H.Depressor Effect of Chymase Inhibitor in Mice with High Salt-Induced Moderate Hypertension. Am J Physiol Heart Circ Physiol.2015309(11):H1987-96
  • Norimatsu K, Miura S, Suematsu Y, Shiga Y, Miyase Y, Nakamura A, Zhang B, Saku K.Association between pentraxin 3 levels and aortic valve calcification. Journal of Cardiology. 2015, 68:76-82
  • Miyase Y, Miura S, Shiga Y, Yano M, Suematsu Y, Adachi S, Norimatsu K, Nakamura A, Saku K.Association between the severity of coronary artery stenosis and the combination of the difference in blood pressure between arms and brachial-ankle pulse wave velocity.Clin Exp Hypertens. 2015.Epub ahead of print
  • Shiga Y, Miura S, Adachi S, Suematsu Y, Sugihara M, Iwata A, Yahiro E, Nishikawa H, Ogawa M, Saku K.Visit-to-Visit Variability and Seasonal Variation in Blood Pressure With Single-Pill Fixed-Dose Combinations of Angiotensin II Receptor Blocker/Calcium Channel Blocker and Angiotensin II Receptor Blocker/Diuretic in Hypertensive Patients. J Clin Med Res.2015.(10):802-6
  • Imaizumi S, Miura S, Takata K, Takamiya Y, Kuwano T, Sugihara M, Ike A, Iwata A, Nishikawa H, Saku K.Association between cholesterol efflux capacity and coronary restenosis after successful stent implantation. Heart Vessels. 2015, 31:1257-1265
  • Suematsu Y, Miura S, Zhang B, Uehara Y, Ogawa M, Yonemoto N, Nonogi H, Nagao K, Kimura T, Saku K.Association between dental caries and out-of-hospital cardiac arrests of cardiac origin in Japan. Journal of Cardiology. 2015, 67:384-391
  • Gondo K, Miura S, Suematsu Y, Shiga Y, Kuwano T, Sugihara M, Ike A, Iwata A, Motozato K, Kusumoto T, Nishikawa H, Saku K.Association Between Visit-to-Visit Variability in Blood Pressure and Cardiovascular Events in Hypertensive Patients After Successful Percutaneous Coronary Intervention. J Clin Med Res.2015.7(7):545-50
  • Yamamoto T, Miura S, Suematsu Y, Kuwano T, Sugihara M, Ike A, Iwata A, Nishikawa H, Saku K.A relative difference in systolic blood pressure between arms by synchronal measurement and conventional cardiovascular risk factors are associated with the severity of coronary atherosclerosis. Heart Vessels. 2015, 31:863-870
  • Miura S, Nakayama A, Tomita S, Matsuo Y, Suematsu Y, Saku K.Comparison of aldosterone synthesis in adrenal cells, effect of various AT1 receptor blockers with or without atrial natriuretic peptide. Clinical and Experimental Hypertension.2015.37(5):353-357
  • Morito N, Miura S, Yano M, Hitaka Y, Nishikawa H, Saku K.Association between a ban on smoking in a hospital and the in-hospital onset of acute myocardial infarction. Cardiol Res.2015.6(3):278-282.
  • Yahiro E, Kawachi E, Miura S, Kuwano T, Imaizumi S, Iwata A, Hasegawa K, Yano T, Watanabe Y, Uehara Y, Saku K. Comparison of 64Cu and 68Ga for Molecular Imaging of Atherosclerosis using the Apolipoprotein A-I Mimetic Peptide FAMP.J Cardiovasc Dis Diag.2015.3:201. doi:10.4172/2329-9517.1000201
  • Fujimi K, Miura S, Matsuda T, Fujita M, Ura Y, Kaino K, Sakamoto M, Hirota T, Arimura T, Shiga Y, Saku K. Influence of a cardiac rehabilitation program on renal function in patients with cardiovascular disease in a 1-year follow-up. Cardiol Res.2015.6(4-5):311-315
  • Tokunaga M*, Suematsu Y*, Miura S, Kuwano T, Iwata A, Nishikawa H, Zhang B, Yonemoto N, Nonogi H, Nagao K, Kimura T, Saku K.(*co-first authors)On behalf of the Japanese Circulation Society Resuscitation Science Study (JCS-ReSS) Group. Association between the consumption of carbonated beverages and out-of-hospital cardiac arrests of cardiac origin in Japan. World J Cardiovasc Dis.2015.5:361-372
  • Takata K, Imaizumi S, Zhang B, Miura S, Saku K.Stabilization of high-risk plaques.Cardiovasc Diagn Ther.2015.doi: 10.3978/j.issn.2223-3652
  • Yasunaga T, Yasuno T, Imaizumi S, Nakashima H.The Use of Multiplex Ligation Dependent Probe Amplification Technology for Genetic Analysis of the Entire PKD1 Gene and PKD2 Gene. J Clin Med Case Reports.2015.2(1):3
  • Nagata I, Ike A, Nishikawa H, Sugihara M, Mori K, Iwata A, Kawamura A, Shirai K, Zhang B, Miura S, Saku K. Significant differences in lipid profile associated with MACEs between hemodialysis and non-HD patients from FU-Registry. J Cardiol. 2015;65:105-111.
  • Gondo K, Miura S, Suematsu Y, Shiga Y, Kuwano T, Sugihara M, Ike A, Iwata A, Motozato T, Kusumoto T, Nishikawa H, Saku K. Association between visit-to-visit variability in blood pressure and cardiovascular events in hypertensive patients after successful percutaneous coronary intervention. J Clin Med Res. 2015;7:545-550.
  • Shimizu T*, Tanigawa H*, Miura S, Kuwano T, Takata K, Suematsu Y, Imaizumi S, Yahiro E, Zhang B, Uehara Y, Saku K. Newly developed apolipoprotein A-I mimetic peptide promotes macrophage reverse cholesterol transport in vivo. Int J Cardiol. 2015;192:82-88. (*co-first authors)
  • Ike A, Shirai K, Yahiro A, Sugihara M, Kawamura A, Iwata A, Uehara Y, Zhnag B, Ogawa M, Mori K, Mura S, Saku K. Association between the use of new and old hypoglycemic agents and the clinical outcome of percutaneous coronary intervention in diabetic patients: - From the FU-Registry -. J Cardiol. 2015;65:390-396.
  • Norimatsu K, Miura S, Suematsu Y, Shiga Y, Miyase Y, Nakamura A, Yamada M, Matsunaga A, Saku K. Associations between glycated albumin or hemoglobinA1c and the presence of coronary artery disease. J Cardiol. 2015;65:487-493.
  • Yahiro E, Kawachi E, Miura S, Kuwano T, Imaizumi S, Iwata A, Hasegawa K, Yano T, Watanabe Y, Uehara Y, Saku K. Comparison of 64Cu and 68Ga for Molecular Imaging of Atherosclerosis using the Apolipoprotein A-I Mimetic Peptide FAMP. J Cardiovasc Dis Diag. 2015;3:201. doi:10.4172/2329-9517.1000201.
  • Morito N, Miura S, Yano M, Hitaka Y, Nishikawa H, Saku K. Association between a ban on smoking in a hospital and the in-hospital onset of acute myocardial infarction. Cardiol Res. 2015;6:278-282.
  • Shiga Y, Miura S, Norimatsu K, Hitaka Y, Nagata I, Morii J, Kuwano T, Uehara Y, Inoue A, Shirotani T, Fujisawa K, Matsunaga E, Saku K. Efficacy and safety of combination therapy of high-dose losartan and hydrochlorothiazide in patients with hypertension. J Renin Angiotensin Aldosterone Syst. 2015. in press.
  • Miura S, Nakayama A, Tomita S, Matsuo Y, Suematsu Y, Saku K. Comparison of aldosterone synthesis in adrenal cells, effect of various AT1 receptor blockers with or without atrial natriuretic peptide. Clin Exp Hypertens. 2015. in press.
  • Yamamoto T, Miura S, Suematsu Y, Kuwano T, Sugihara M, Ike A, Iwata A, Nishikawa H, Saku K. A relative difference in systolic blood pressure between arms by synchronal measurement and conventional cardiovascular risk factors are associated with the severity of coronary atherosclerosis. Heart Vessels. 2015. in press.
  • Miyase Y, Miura S, Shiga Y, Yano M, Suematsu Y, Adachi S, Norimatsu K, Nakamura A, Saku K.Association between the severity of coronary artery stenosis and the combination of the difference in blood pressure between arms and brachial-ankle pulse wave velocity. Clin Exp Hypertens. 2015, 38:81-88
  • Motozato K, Miura S, Shiga Y, Kusumoto T, Adachi S, Inoue T, Fujisawa K, Saku K. Efficacy and safety of two single-pill fixed-dose combinations of angiotensin II receptor blockers/calcium channel blockers in hypertensive patients (EXAMINER study). Clin Exp Hypertens. 2015. in press.
  • Yohiro E, Miura S, Suematsu Y, Matsuo Y, Arimura T, Kuwano T, Imaizumi S, Iwata A, Uehara Y, Saku K. Addition of a nitric oxide donor to an angiotensin II type 1 receptor blocker may cancel its blood pressure-lowering effects. Int Heart J. 2015. in press.
  • Suematsu Y, Miura S, Zhang B, Uehara Y, Ogawa M, Yonemoto N, Nonogi H, Nagao K, Kimura T, Saku K, on behalf of the Japanese Circulation Society Resuscitation Science Study (JCS-ReSS) Group. Association between dental caries and out-of-hospital cardiac arrests of cardiac origin in Japan. J Cardiol. 2015. in press.
  • Yano M, Miura S, Shiga Y, Miyase Y, Suematsu Y, Norimatsu K, Nakamura A, Adachi S, Nishikawa H, Saku K. Association between smoking habits and severity of coronary stenosis as assessed by coronary computed tomography angiography. Heart & Vessels. 2015. in press.
  • Shiga Y, Miura S, Adachi S, Suematsu Y, Sugihara M, Iwata A, Yahiro E, Nishikawa H, Ogawa M, Saku K. Visit-to-visit variability and seasonal variation in blood pressure with single-pill fixed-dose combinations of angiotensin II receptor blocker/calcium channel blocker and angiotensin II receptor blocker/diuretic in hypertensive patients. J Clin Med Res. 2015. in press.

2014年

  • Miura SI, Matsuo Y, Nakayama A, Tomita S, Suematsu Y, Saku K. Ability of the new AT1 receptor blocker azilsartan to block angiotensin II-induced AT1 receptor activation after wash-out. J Renin Angiotensin Aldosterone Syst 15(1):7-12, 2014
  • Serikawa T, Miura S, Okabe M, Hongo H, Tokutome M, Yoshikawa T, Takesue K, Adachi S, Osaka K, Matsukawa R, Yanagi D, Nozoe M, Kozai T, Hironaga K, Saku K, Yamamoto Y. The ratio of eicosapentaenoic acid to arachidonic acid is a critical risk factor for acute coronary syndrome in middle-aged older patients as well as younger adult patients. Journal of Cardiology 63(1):35-40, 2014
  • Suematsu Y, Miura S, Zhang B, Uehara Y, Tokunaga M, Yonemoto N, Nonogi H, Nagao K, Kimura T, Saku K. Associations between the consumption of different kinds of seafood and out-of-hospital cardiac arrests of cardiac origin in Japan. IJC Heart & Vessels 2:8-14, 2014
  • Nakamura A, Miura SI, Sugihara M, Miyase Y, Norimatsu K, Shiga Y, Nishikawa H, Saku K. Contrast between innovator drug- and generic drug-induced renal dysfunction on coronary angiography (CONTRAST study). Heart Vessels 29(5):603-610, 2014
  • Nagata I, Shiga Y, Miura S, Norimatsu K, Hitaka Y, Morii E, Kuwano T, Inoue A, Fujisawa K, Shirotani T, Matsunaga E, Uehara Y, Saku K. Comparison of the efficacy and safety of single-pill fixed-dose combinations of olmesartan/azelnidipine and valsartan/amlodipine in patients with hypertension (RENOVATE Study). Exp Clin Cardiol 20(1):1920-1938, 2014
  • Miyase Y, Miura S, Shiga Y, Nakamura A, Norimatsu K, Nishikawa H, Saku K. The ratio of low-frequency to high-frequency in ambulatory electrocardiographic monitoring immediately before coronary angiography as a predictor of the presence of coronary artery disease. J Clin Med Res 6(1):36-43, 2014
  • Sakai T, Sato B, Hara K, Hara Y, Naritomi Y, Koyanagi S, Hara H, Nagao T, Ishibashi T. Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function. Vasc Health Risk Manag 17;10:591-7, 2014
  • Ishibashi T, Sato B, Shibata S, Sakai T, Hara Y, Naritomi Y, Koyanagi S, Hara H, Nagao T. Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: a randomized, double-blind, placebo-controlled pilot study. Int Immunopharmacol 21(2):468-73, 2014
  • Yamaguchi S, Zhang B, Tomonaga T, Seino U, Kanagawa A, Segawa M, Nagasaka H, Suzuki A, Miida T, Yamada S, Sasaguri Y, Doi T, Saku K, Okazaki M, Tochino Y, Hirano K. Selective evaluation of high density lipoprotein from mouse small intestine by an in situ perfusion technique. J Lipid Res 55(5):905-18, 2014
  • Shiga Y, Miura S, Nishikawa H, Sugihara H, Nakashima Y, Takamatsu Y, Koga K, Koga S, Katayama Y, Yoshida T, Iwasaki H, Saku K. Very rare case of large obstructive myxofibrosarcoma of the right ventricle assessed with multi-diagnostic imaging techniques. Intern Med 53(7):739-42, 2014
  • Nakamura A, Miura SI, Sugihara M, Miyase Y, Norimatsu K, Shiga Y, Nishikawa H, Saku K. Is pentraxin 3 a biomarker, a player, or both in the context of coronary atherosclerosis and metabolic factors? Heart Vessels Epub ahead of print, 2014
  • Shimizu T, Miura S, Tanigawa H, Kuwano T, Zhang B, Uehar Y, Saku K. Rosvastatin activates ATP-binding cassette transporter A-1 dependent efflux ex vivo and promotes reverse cholesterol transport in macrophage cells in mice fed a high-fat diet. Arterioscler Thromb Vasc Biol 34(10):2246-2253, 2014
  • Shiga Y, Miura SI, Norimatsu K, Hitaka Y, Nagata I, Koyoshi R, Morii J, Kuwano T, Uehara Y, Inouye A, Shirotani T, Fujisawa K, Matsunaga E, Saku K. Efficacy and Safety of combination therapy of high-dose losartan and hydrochlorothiazide in patients with hypertension. J Renin Angiotensin Aldosterone Syst Epub ahead of print, 2014
  • Takata K, Imaizumi S, Kawachi E, Suematsu Y, Shimizu T, Abe S, Matsuo Y, Tsukahara H, NodaK, Yahiro E, Zhang B, Uehara Y, Miura S, Saku K. Impact of cigarette smoking cessation on high-density lipoprotein functionality. Circulation Journal 25;78(12):2955-62, 2014
  • Fujimi K, Miura S, Fujita M, Ura Y, Kaino K, Horita T, Matsuda T, Hirota Y, Ogawa M, Saku K. Effects of Cardiac Rehabilitation in Patients with Cardiac Resynchronization Therapy. Exp Clin Cardiol 20:3565-3568, 2014
  • Norimatsu K, Miura S, Suematsu Y, Shiga Y, Yano M, Hitaka Y, Kuwano T, Morii J, Yasuda T, Ogawa M, Saku K. Assessment of the circadian variation in the anticoagulant effect of rivaroxaban using a novel automated microchip flow-chamber system for the quantitative evaluation of thrombus formation. IJC Heart & Vessels 218-220, 2014
  • Miura S, Suematsu Y, Matsuo Y, Imaizumi S, Yahiro E, Uehara Y, Saku K. Induction of endothelial tube formation and anti-inflammation by newly developed apolipoprotein A-I mimetic peptide. IJC Metabolic & Endocrine 70-72, 2014
  • Yahiro E, Uehara Y, Kawachi E, Ando S, Miura S, Saku K. Improved survival rate after myocardial infarction using an inducible cholesterol efflux peptide: FAMP. Heart Vessels 135-137, 2014
  • Nagata Y, Miura S, Suematsu Y, Sugihara M, Ike A, Iwata A, Nishikawa H, Kawamura A, Saku K. Association between major adverse cardiovascular events and brachial-ankle pulse wave velocity and a difference in blood pressure between arms after percutaneous coronary intervention. Exp Clin Cardiol 4838-4848, 2014
  • Yamamoto T, Miura S, Shiga Y, Miyase Y, Nakamura A, Ike A, Sugihara M, Iwata A, Nishikawa H, Saku K. Association between mild myocardial injury post percutaneous coronary intervention and improvement of cardiac function through an increase in tissue inhibitor of metalloproteinase-1. Exp Clin Cardiol 4849-4855, 2014
  • Fujimi K, Miura S, Sugihara M, Fujita M, Ura Y, Kaino K, Horita T, Matsuda T, Ike A, Nishikawa H, Saku K. Impact of a cardiac rehabilitation program on cardiac function after acute myocardial infarction. Exp Clin Cardiol 20:3561-3564, 2014
  • Yamamoto T, Miura S, Shiga Y, Nagata Y, Miyase Y, Suematsu Y, Uehara Y, Saku K. A relative difference in blood pressure between arms by synchronal measurement is associated with hypertension. Exp Clin Cardiol 6574-6578, 2014
  • Kawamura A, Miura S, Matsuo Y, Tanigawa H, Saku K. Azelnidipine-, but not amlodipine-, induced secretion of vascular endothelial growth factor from smooth muscle cells promotes endothelial tube formation. Cardiol Res 145-150, 2014
  • Bhimani AA, Yasuda T, Sadrpour SA, Khrestian CM, Lee S, Zeng D, Belardinelli L, Waldo AL. Ranolazine terminates atrial flutter and fibrillation in a canine model. Heart Rhythm 11(9):1592-1599, 2014
  • Yang Y,Kuwano T,Lagor WR,Albert CJ,Brenton S,Rader DJ,Ford DA,Brown RJ. Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species. Lipids 49(6):505-515, 2014

2013年

  • Saku K, Iwata A. (JCS Joint Working Group) Guidelines for Secondary Prevention of Myocardial Infarction (JCS 2011). -Digest Version- JCS Joint Working Group Circulation Journal 77(1): 231-248, 2013
  • Miura S, Okabe A, Matsuo Y, Karnik SS, Saku K. Unique binding behavior of the recently approved angiotensin Ⅱreceptor blocker azilsartan compared with that of candesartan. Hypertension Research 36:134-139, 2013
  • Sugihara M, Miura S, Nishikawa H,Ike A, Mori K, Iwata A, Kawamura A, Saku K. Characteristics of patients and types of lesions in patients with drug-eluting or bare-metal stent implantation in small coronary arteries From the FU-Registry. Journal of Cardiology 61:117-121, 2013
  • The Anti-Smoking Promotion Committee of the Japanese Circulation Society. Saku K, Iida M, Uehara Y, Ebina T, Murohara T, Takihara K, Higaki J, Takahashi Y, Fujiwara H. Anti-Smoking Declaration 2013 -A Message From the Japanese Circulation Society-. Circulation Journal 77(3): 559-560, 2013
  • Uehara Y, Ando S, Yahiro E, Oniki K, Ayaori M, Abe S, Kawachi E, Zhang B, Shioi S, Tanigawa H, Imaizumi S, Miura S, Saku K. FAMP, a Novel ApoA-I Mimetic Peptide, Suppresses Aortic Plaque Formation Through Promotion of Biological HDL Function in ApoE-Deficient Mice. J Am Heart Assoc. May 24;2(3), 2013
  • Kawachi E, Uehara Y, Hasegawa K, Yahiro E, Ando S, Wada Y, Yano T, Nishikawa H, Shiomi M, Miura S, Watanabe Y, Saku K. Novel molecular imaging of atherosclerosis with gallium-68-labeled apolipoprotein A-I mimetic peptide and positron emission tomography. Circ J. 77(6):1482-9, 2013
  • JCS Joint Working Group. Saku K. (Independent Assessment Committee) Guidelines for Treatment of Acute Heart Failure (JCS 2011) -Digest Version-. Circulation Journal 77(8): 2157-2201, 2013
  • Suematsu Y, Murasato Y, Miura S, Horiuchi M, Yamamoto T, Takata K, Saku K. Safety and feasibility of high-dose administration of nicorandil before reperfusion therapy in acute myocardial infarction. Cardiovascular Intervention Therapeutics. 28(4):352-61, 2013
  • Tanaka T, Miura S, Tanaka M, Uehara Y, Hirano T, Saku K. Efficacies of Controlling Morning Blood Pressure and Protecting the Kidneys by Treatment With Valsartan and Nifedipine CR or Valsartan and Amlodipine (MONICA Study). J Clin Med Res 5(6):432-40, 2013
  • Uehara Y, Fujimi K, Yahiro E, Abe S, Devarajan S, Saku K, Urata H. Induction of tissue angiotensin Ⅱ-forming activity in two-kidney, one-clip hypertensive hamster model. World Journal of Hypertension 3(2):9-17, 2013
  • Kumagai N, Miura S, Zhang B, Noda K, Saku K, Zenith Trial Investigators. Effects of ezetimibe on hypercholesterolemia in the lipid profile patients with metabolic syndrome : Zenith Trial. IJC Metabolic & Endocrine 7月12日, 2013
  • Morii J, Miura S, Ike A, Shiga Y, Sugihara M, Iwata A, Kawamura A, Nishikawa H, Saku K. Comparison of the efficacies of irbesartan and olmesartan after successful coronary stent implantation. Intern Med. 52(7):713-9, 2013
  • Miura S, Nakao N, Hanzawa H, Matsuo Y, Saku K, Karnik SS. Reassessment of the unique mode of binding between angiotensin II type 1 receptor and their blockers. PLoS One. 8;8(11):e79914., 2013
  • Nakamura A, Miura SI, Sugihara M, Miyase Y, Norimatsu K, Shiga Y, Nishikawa H, Saku K. Contrast between innovator drug- and generic drug-induced renal dysfunction on coronary angiography (CONTRAST study). Heart Vessels Epub ahead of print, 2013

2012年

  • Shiga Y, Miura SI, Mitsutake R, Uehara Y, Inoue A, Saku K. Effect of fixed-dose losartan/hydrochorothiazide on brain natriuretic peptide in patients with hypertension. J Renin Angiotensin Aldosterone Syst. 13(1):107-112, 2012
  • Kiya Y, Miura S, Matsuo Y, Karnik SS, Saku K. Abilities of candesartan and other AT1 receptor blockers to impair angiotensin Ⅱ-induced AT1 receptor activation after washout. J Renin Angiotensin Aldosterone Syst. 13(1):76-83, 2012
  • Nakamura A, Uehara Y, Kawamura A, Saku K. Giant Thrombus Filling the Pulmonary Trunk. INTERNAL MEDICINE 51(1):333, 2012
  • Saku K. Guidelines for Smorking Cessation (JCS2010) -Digest Version- JCS Joint Working Group Circulation Journal 76(4):1024-1043, 2012
  • Chen PS, Ogawa M, Maruyama M, Chua SK, Chang PC, Rubart-von der Lohe M, Chen Z, Ai T, Lin SF. Imaging Arrhythmogenic Calcium Signaling in Intact Hearts. Pediatr Cardiol 33(6):968-974, 2012
  • Noda K, Zhang B. Iwata A, Nishikawa H, Ogawa M, Nomiyama T, Miura S, Sako H, Matsuo K, Yahiro E, Yanase T, Saku K, on behalf of the STYLIST Study Investigators. Lifestyle changes through the use of delivered meals and dietary counseling in a single-blind study. The STYLIST study. Circulation Journal 76(6):1335-1344, 2012
  • Koyoshi R, Miura S, Kumagai N, Shiga Y, Mitsutake R, Saku K. Clinical Significance of Flow-Mediated Dilation, Brachial Intima-Media Thickness and Pulse Wave Velocity in Patients With and Without Coronary Artery Disease. Circulation Journal 76(6):1469-1475, 2012
  • Fukuda Y, Sumi-Inoue Y, Matsumoto K, Kubota K, Sumi S, Tojo H, Yamanouchi Y, Miura S, Saku K, Urata H. Pleiotropic Effects of High-dose losartan on Uricosuria and Increased High Molecular Weight Adioponectin in Hypertensive Patients Therapeutic Research 33(2):221-228, 2012
  • Fukushima M, Miura S, Mitsutake R, Fukushima T, Fukushhima K, Saku K. Cholesterol Metabolism in Patients With Hemodialysis in the Presence or Absence Coronary Artery Disease. Circulation Journal 76(8):1980-1986, 2012
  • Zhang B, Kawachi E, Matsunaga A, Imaizumi S, Noda K, Uehara Y, Miura S, Yoshinaga K, Kuroki M, Saku K. Reactivity of direct assays for low-density lipoprotein (LDL) cholesterol toward charge-modified LDL in hypercholesterolemia. Circulation Journal 76(9):2241-2248, 2012
  • Arimura T, Miura S, Ike A, Sugihara M, Iwata A, Nishikawa H, Kawamura A, Saku K. Comparison of the efficacy and safety of statin and statin/ezetimibe therapy after coronary stent implantation in patients with stable angina. Journal of Cardiology 60:111-118, 2012
  • Shiga Y, Miura S, Hitaka Y, Saku K. Right aortic arch with Kommerell's diverticulum using 64-MDCT. Intern Med. 51(11):1437-1438, 2012
  • Shiga Y, Miura S, Mitsutake R, Norimatsu K, Nagata I, Arimura T, Shimizu T, Morii J, Kuwano T, Uehara Y, Inoue A, Shirotani T, Fujisawa K, Matsunaga E, Saku K. Efficacy and safety of a single-pill fixed-dose combination of high-dose telmisartan/hydrochlorothiazide in patients with uncontrolled hypertension. J Renin Angiotensin Aldosterone Syst. 13(3):394-400, 2012
  • Devarajan A, Grijalva VR, Bourquard N, Meriwether D 3rd, Imaizumi S, Shin BC, Devaskar SU, Reddy ST. Macrophage paraoxonase 2 regulates calcium homeostasis and cell survival under endoplasmic reticulum stress conditions and is sufficient to prevent the development of aggravated atherosclerosis in paraoxonase 2 deficiency/apoE(-/-) mice on a Western diet. Mol Genet Metab 107(3):416-27, 2012
  • Su F, Grijalva V, Navab K, Ganapathy E, Meriwether D, Imaizumi S, Navab M, Fogelman AM, Reddy ST, Farias-Eisner R. HDL mimetics inhibit tumor development in both induced and spontaneous mouse models of colon cancer. Mol Cancer Ther. 11(6):1311-1319, 2012
  • Miura S, Kiya Y, Hanzawa H, Nakao N, Fujino M, Imaizumi S, Matsuo Y, Yanagisawa H, Koike H, Komuro I, Karnik SS, Saku K. Small molecules with similar structures exhibit agonist, neutral antagonist or inverse agonist activity toward angiotensin II type 1 receptor. PLoS One 7(6):e37974, 2012
  • Tang L, Joung B, Ogawa M, Chen PS, Lin SF. Intracellular Calcium Dynamics, Shortened Action Potential Duration, and Late-Phase 3 Early Afterdepolarization in Langendorff-Perfused Rabbit Ventricles. J Cardiovasc Electrophysiol 23(12):1364-1371, 2012
  • Machida M, Miura S, Matsuo K, Ishikura H, Saku K. Effect of intravenous adrenaline before arrival at the hospital in out-of-hospital cardiac arrest. Journal of Cardiology 60:503-507, 2012
  • Piccirillo G, Magri D, Pappada MA, Maruotti A, Ogawa M, Han S, Joung B, Rossi P, Nguyen BL, Lin SF, Chen PS. Autonomic nerve activity and the short-term variability of the Tpeak-Tend interval in dogs with pacing-induced heart failure Heart Rhythm Society 2044-2050, 2012
  • Ayaori M, Yakusiji E,Ogura M,Nakaya K,Hisada T,Uto-Kondo H,Takiguchi S,Terao Y,Sasaki M,Komatu T,Iizuka M,Yogo M,Uehara Y,Kagechika H,Nakanisi T,Ikewaki K Retinoic Acid receptor agonists regulate expression of ATP-binding cassette transporter G1 in macrophages. Biochimica et Biophysica Acta 1821(4):561-72, 2012
  • Morii J, Miura S, Shiga Y, Sugihara M, Arimura T, Sako H, Zhang B, Uehara Y, Saku K. Comparison of the efficacy and safety of irbesartan and olmesartan in patients with hypertension (EARTH study). Clin Exp Hypertens. 34(5):342-9, 2012
  • Shimizu T, Miura S, Takeuchi K, Tashiro T, Saku K. Effects of gender and aging in patients who undergo coronary artery bypass grafting: From the FU-Registry Cardiol J 19(6):618-24, 2012
  • Iwata A, Miura S, Tanaka T, Ike A, Sugihara M, Nishikawa H, Kawamura A, Saku K. Plasma pentraxin-3 levels are associated with coronary plaque vulnerability and are decreased by statin. Coron Artery Dis. 23(5):315-21., 2012

2011年

  • Takamiya Y, Miura S, Tsuchiya Y, Fukuda Y, Zhang B, Kuwano T, Ike A, Yanagi D, Kubota K, Mori K, Iwata A, Nishikawa H, Kawamura A, Miller N, Matsuo K, Shirai K, Saku K. Angiographic late lumen loss at the site of overlap of multiple CypherTM sirolimus-eluting stents: ALSOCE study. Journal of Cardiology 57(2):187-193 2011
  • Ike A, Nishikawa H, Shirai K, Mori K, Kuwano T, Fukuda Y, Takamiya Y, Yanagi D, Kubota K, Tsuchiya Y, Zhang B, Miura S, Saku K. Impact of Glycemic Control on the Clinical Outcome in Diabetic Patients With Percutaneous Coronary intervention - From the FU-Rsgistry -. Circulation Journal 75(4):791-799, 2011
  • Chua SK, Chang PC, Maruyama M, Turker I, Shinohara T, Shen MJ, Chen Z, Shen C, Rubart-von der Lohe M, Lopshire JC, Ogawa M, Weiss JN, Lin SF, Ai T, Chen PS. Small-conductance calcium-activated potassium channel and recurrent ventricular fibrillation in failing rabbit ventricles. Circ Res. 108:971-979 2011
  • Saku K, Zhang B, Noda K, The PATROL Trial Investigators. Randomized Head-to-Head Comparison of Pitavastatin, Atorvastatin, and, Rosuvastatin for Safety and Efficacy (Quantity and Quality of LDL) - The PATROL Trial - Circulation Journal. 75:1493-1505, 2011
  • Imaizumi S. Intestine may be a major site of action for the apoA-l mimetic peptide 4F whether administered subcutaneously or orally. Journal of Lipid Research 52:1200-1210, 2011
  • Imaizumi S. Human CYP2S1 Metabolizes Cyclooxygenase-and Lipoxygenase-Derived Eicossanoids. DRUG METAB DISPOS 39:180-190 2011
  • Imaizumi S L-5F, an apolipoprotein A-I mimetic inhibits tumor angiogenesis by suppressing VEGF/basic FGF signaling pathways. Integrative Biology 3:479-489 2011
  • Mitsutake R, Miura S, Shiga Y, Uehara Y, Saku K. Association Between Hypertension and coronary Artery Disease as Assessed by Coronary Computed Tomography. J of Clinical Hypertension 13(3):198-204, 2011
  • Kuwano T, Miura S, Shirai K, Ike A, Mori K, Shimizu T, Zhang B, Iwata A, Nishikawa H, Kawamura A, Saku K. Serum Levels of Bilirubin as an Independent Predictor of Coronary In-Stent Restenosis: A New Look at an Old Molecule. Journal of Atherosclerosis and Thrombosis 18(7):574-583 2011
  • Swaminathan PD, Purohit A, Soni S, Voigt N, Singh MV, Glukhov AV, Gao Z, He BJ, Kuczak ED, Joiner ML, Kutschke W, Yang J, Donahue JK, Weiss RM, Grumbach IM, Ogawa M, Chen PS, Efimov I, Dobrev D, Mohler PJ, Hund TJ, Anderson ME. Oxidized CaMKⅡ causes sinus node dysfunction in mice. J Clin Invest Equb ahead of print 2011
  • Takahira M, Noda K, Fukushima M, Zhang B, Mitsutake R, Uehara Y, Ogawa M, Kakuma T, Saku K. Randomized Double-Blind Controlled Comparative Trial of Food Containing Soy Protein vs.Milk Protein in Visceral Fat Obesity. -FLAVO Study- Circulation Journal 75(9):2235-2243 2011
  • Shiga Y, Miura S, Mitsutake R, Yamagishi S, Saku K. Significance of Plasma Levels of Pigment Epithelium-derived Factor as Determined by Multidetector Row Computed Tomography in Patients with Mild Chronic Kidney Disease and/ or Coronary Artery Disease. J Int Med Res. 39:(3)880-890 2011
  • Morgantini C, Natali A, Boldrini B, Imaizumi S, Nadab M, Fogelman AM, Ferrannini E, Reddy ST. Anti-inflammatory and Antioxidant Properties of HDLs Are lmpaired in Type 2 Diadetes. Diabetes 60(10):2617-23, 2011
  • Meriwether D, Imaizumi S, Grijalva V,Hough G, Vakili L, Anantharamaiah GM, Farias-Eisner R, Navab M, Fogelman AM, Reddy ST, Shechter I. Enhancement by LDL of transfer of L-4F and oxidized lipids to HDL in C57BL/6J mice and human plasma J Lipid Res 52(10):1795-809 2011
  • Kitajima K,Miura S, Yamagushi T, Uehara Y, Kiya Y, RyeKA, Kadowaki T, Saku K. Possibility of increasing cholesterol efflux by adiponectin and its receptors through the ATP binding cassette transporter A1 in HEK293T cells. Biochem Biophys Res Commun. 411:305-311 2011
  • Sugihara M, Miura S, Takamiya Y, Kiya Y, Arimura T, Iwata A, Kawamura A, Nishikawa H, Yamagishi S, Saku K. Significance of pigment spithelium-derived factor levels with angiotensin Ⅱ type 1 receptor blokers in patients with successful colonary stent implantation. J Renin Angiotensin Aldosterone Syst. 12:320-325 2011
  • Iwata A, Miura S, Morii J, Yamagishi S, Saku K. Association between plasma pigment epithelium-derived factor levels and tissue characteristics of coronary plaque using integrated backscatter intravascular ultrasound. Intern Med. 50:1889-1894 2011
  • Arimura T, Miura S, Sugihara M, Iwata A, Yamagishi S, Saku K. Association Between plasma levels of pigment epithelium-derived factor and renal dysfunction in patients with coronary artery disease. Cardiol J 18:515-520 2011
  • Iwata A, Miura S, Zhang B, Imaizumi S, Uehara Y, Shiomi M, Saku K. Antiatherogenic effects of newly-developed apolipoprotein A-I mimetic peptide/ phospholipid complexes against aortic plaque burden in Watanabe-heritable hyperlipidemic rabbits. Atherosclerosis 218:300-307 2011
  • Mito T, Miura S, Iwata A, Morii J, Sugihara M, Ike A, Mori K, Kawamura A, Nishikawa H, Zhang B, Saku K. Determination of the cut-off plasma adiponectin level assosiated with a lower risk of restenosis in patients with stable angina. Coronary Artery Dis. 22:451-457 2011
  • Shiga Y, Miura S, Morii J, Kuwano T, Mitsutake R, Uehara Y, Inoue A, Saku K. Comparison of the efficacy and safety of Single-pill fixed-dose combinations of Losartan / hydrochlorothiazide and Valsartan / hydrochlorothiazide in patients with hypertension (SALT-VAT study). Intern Med. 50(21):2477-2483 2011
  • Morito N, Miura S, Saku K. Changes in the baseline clinical characteristics of hospitalized patients with congestive heart failure. Med Bull Fukuoka Univ.(福岡大医学紀要) 38(4):171-176 2011
  • Saraswathi R, Sankar D, Ali A, Uehara Y, Abe S, Sambandam G, Rao MR. A Pilot Assessment of Oxidative Stress Byproducts and Antioxidant Activities Among Indian Patients with Various Stages of Hypertension. Clin Exp Hypertens 33(7):437-443, 2011
  • Baba Y, Higuchi MA, Fukuyama K, Abe H, Uehara Y, Inoue T, Yamada T. Effect of chronic kidney disease on excessive daytime sleepiness in Parkinson disease. Eur J Neurol 18(11):1299-303 2011
  • Serikawa T, Kawasaki T, Koga H, Orita Y, Ikeda S, Goto Y, Shintani Y, Kajiwara M, Tanaka H, Fukuyama T, Koga N. Late catch-up phenomenon associated with stent fracture after sirolimus-eluting stent implantation: incidence and outcome. J Interv Cardiol. 24(2):165-71 2011
  • Ozasa H, Ayaori M, Iizuka M, Terao Y, Uto-KOndo H, Yakushiji E, Takiguchi S, Nakaya K, Hisada T, Uehara Y, Ogura M, Sasaki M, Komatsu T, Horii S, Mochizuki S, Yoshimura M, Ikewaki K. Pioglitazone enhances cholesterol efflux from macrophages by increasing ABCA1/ACG1 expressions via PPARγ /LXRαpathway: findings from in vitro and ex vivo studies. Atherosclerosis 219:141-15, 2011
  • Arishima H, Matsunaga A, Uehara Y, Niimura H, Zhang B, Ohwaki K, Hayashida K, Yoshimizu K, Saku K. Statins Induce the Gene Expression of Apolipoprotein A5 in HepG2 Cells. Med.Bull.Fukuoka Univ.(福岡大学医学紀要) 38(4):161-169 , 2011
  • Fukuda Y, Miura S, Tsuchiya Y, InoueY, Kubota K, Takamiya Y, Kuwano T, Ohishi H, Ike A, Mori K, Yanagi D, Nishikawa H, Shirai K, Saku K, Urata H. Lower frequency of non-target lesion intervention in post-successful percutaneous coronary intervention patients with an LDL to HDL cholesterol ratio below 1.5. International Journal of Cardiology 149(1):120-122 2011

2010年

  • Miura SI, Saku K. Do angiotensin II type 1 receptor blockers have molecular effects? Hypertens Res. 2010; 33(2):105-106.
  • Miura SI, Matsuo Y, Kiya Y, Karnic SS, Saku K. Molecular mechanisms of the antagonistic action between AT(1) and AT(2) receptors. Biochem Biophys Res Commun. 2010; 391(1):85-90.
  • Takashima H, Kumagai K, Matsumoto N, Yasuda T, Nakashima H, Yamaguchi Y, Hida S, Muraoka S, Mitsutake C, Miura S, Saku K. Characteristics of the conduction of the left atrium in atrial fibrillation using non-contact mapping. Journal of Cardiology. 2010; 56,166-175.
  • Tobina T, Michishita R, Yamasawa F, Zhang B, Sasaki H, Tanaka H, Saku K, Kiyonaga A. Association between the angiotensin I-converting enzyme gene insertion/delition polymorphism and endurance running speed in Japanese runners. J Physiol Sci. 2010; 60:325-330.
  • Buga GM, Navab M, Imaizumi S, Reddy ST, Yetka B, Hough G, Anantharamaiah GM, Fogelman AM. L-4F, an Apolipoprotein A-Ⅰ Mimetic, Inhibits Platelet Aggregation and Prolongs Bleeding Time by Inhibiting the Formation of Arachidonic Acid Metabolites in Apo-E Null Mice. Arterioscler Thoromn Vasc Biol. 2010; 30(2):283-289.
  • Imaizumi S, Kiya Y, Miura S, Zhang B, Matsuo Y, Uehara Y, Rye KA, Saku K. Pharmacological intervention using reconstituted high-density lipoprotein changes in the lipid profile in spontaneously hypersensitive rats. Clin Exp Hypertens. 2010; 32(3):202-208.
  • Imaizumi S, Grijalva V, Navab M, Van Lenten BJ, Wagner AC, Anantharamiah GM, Fogelman AM, Reddy ST. L-4F differenrially alters plasma levels of oxidized fatty acids resulting in more anti-inflammatory HDL in mice. Drug Metab Lett. 2010; 4(3):139-48.
  • Imaizumi S, Grijalva V, Priceman S, Wu L, Su F, Farias-Eisner R, Hama S, Navab M, Fogelman AM, Reddy ST. Mitogen-activeted protein kinase phosphatase-1 deficiency decreases atherosclerosis in apolipoprotein E null mice by reducing monocyte chemoattractant protein-1 levels. Mol Genet Metab. 2010;
  • Morgantini C, Imaizumi S, Grijalva V, Navab M, Fogelman AM, Reddy ST. ApoA-ⅠMimetic Peptides Prevent Atherosclerosis Development and Reduce Plaque Inflammation In A Model of Diabetes. Diabetes. 2010;
  • Su F, Kozak K, Imaizumi S, Gao F, Amneus M, Grijalva V, Ng C, Wagner A, Hough G, Farias-Eisner G, Anantharamaiah GM, Van Lenten B, Fogelman AM, Reddy ST, Farias-Eisner R. ApoA-Ⅰ and apoA-Ⅰ Mimetic Peptide Inhibit Tumor Development in a Mouse Model of Ovarian Cancer. Proc Natl Acad Sci U S A. (in press). 2010;
  • Mitsutake C, Muraoka S, Takashima H, Nakashima H, Yasuda T, Matsumoto N, Kumagai K, Saku K. Does Atrial-Pacing from Different Intra-Atrial Sites for Atrial Fibrillation Effect Pulmonary Venous Pressure? Journal of Arrhythmia. 2010; 26(3):176-180.
  • Nishi N,Ogawa M, Morita H, Nakamura K, Banba K, Miura D, Kumagai N, Matsunaga A, Kawamura H, Urakawa S, Miyaji K, Nagai M, Satoh K, Nakagawa K, Tanaka M, Hiramatsu S, Tada T, Murakami M, Nagase S, Kohno K, Kusano KF, Saku K, Ohe T, Ito H. SCN5A Mutation Is Associated With Early and Frequent Recurrence of Ventricular Fibrillation in Patients With Brugada Syndrome. Circulation Journal. 2010; 74(12):2572-2578.
  • Yasuda T, Kumagai K, Ogawa M, Nakashima H, Zhang B, Miura S, Saku K. Comparison of the Effects of Na+ and K+ Channel Blockers on the Electrophysiological Properties of the Pulmonary Veins in Patienties with Atrial Fibrillation. Journal of Arrhythmia. 2010; 26(4):259-266.
  • Shiga Y, Miura S, Mitsutake R, Kawamura A, Uehara Y, Saku K. Significance of serum high-Density lipoprotein cholesterol levels for diagnosis of coronary stenosis as determined by MDCT in patients with suspected coronary artery disease. J Atheroscler Thromb. 2010; 17(8):870-878.
  • Fujino M, Miura S, Kiya Y, Tominaga Y, Matsuo Y, Karnik SS, Saku K. A small difference in the molecular structure of angiotensin II receptor blockers induces AT? receptor-dependent and -independent beneficial effects. Hypertens Res. 2010; 33:1044-1052.
  • Matsumoto N, Kumagai K, Ogawa M, Matsuo K, Yasuda T, Takashima H, Mitsutake C, Muraoka S, Matsunaga A, Miura S, Saku K. Efficacy of Additional Amiodarone Therapy in Patients with an Implantable Cardioverter-Defibrillator. J Arrhythmia. 2010; 26:103-110.
  • Miura S, Saku K. Is a blood pressure rise the only deleterious off-target effect of cholesterol ester transfer protein inhibitors? J Hypertens. 2010; 28(8):1614-1616.
  • Sankar D, Ali A, Raman S, Uehara Y, Ganapathy. Antioxidative capacity of hydrochlorothiazide and atenolol in long-term hypertention therapy. J Chin Clin Med. 2010; 5(3):123-129.
  • Azekoshi Y, Yasu T, Watanabe S, Tagawa T, Abe S, Yamakawa K, Uehara Y, Momomura S, Urata H, Ueda S. FFA causes leukocyte activation and resultant endothelial dysfunction through enhanced angiotensinⅡ production in mononclear and polymorphonuclear cells. Hypertention. 2010; 56(1):136-142.
  • Akazawa H, Yasuda N, Miura S, Komuro I. Assessment of inverse agonism for the angiotensin II type 1 receptor. Methods Enzymol. 2010; 485:25-35.
  • Fujimi K, Uehara Y, Abe S, Kawamura A, Devarajan S, Miura SI, Saku K, Urata H. Homocysteine-induced oxidative stress upregulates chymase in mouse mastocytoma cells. Hypertens Res. 2010; 33:149-154.
  • Fukuda Y, Shirai K, Zhang B, Miller N, Takamiya Y, Kuwano T, Yanagi D, Ike A, Mori K, Kubota K, Iwata A, Nishikawa H, Kawamura A, Costantini CO, Costantini CR, Miura S, Saku K. Factors that Predict Target Lesion Revascularization in Patients with Paclitaxel-eluting Stent Implantation. Medical bulletin of Fukuoka University. 2010; 37(1):1-6.
  • Tsukahara H, Noda K, Saku K. A Randomized Controlled Open Comparative Trial of Varenicline vs Nicotine Patch in Adult Smokers・-Efficacy,Safety and Withdrawal Symptoms (The VN-SEESAW study)-. Circulation Journal. 2010; 74(4):771-778.
  • Wei CC, HaseN, Inoue Y, Bradley EW, Yahiro E, Li M, Naqvi N, Powell PC, Shi K, Takahashi Y, Saku K, Urata H, Dell'ltali. Mast cell chymase limits the cardiac efficacy of Ang l-converting enzyme inhibitor therapy in rodents. The Jounal of Clinical Investigation. 2010; Epub ahead of print.
  • Oniki K, Adachi R, Ando S, Uehara Y, Zhang B, Saku K. Syntfesis of a Peptide Removing Cholesterol from Cell and Its Ability of HDL Formation in Blood Plasma. The Japanese Peptide Society. 2010; 281-284.
  • Kiya Y, Miura S, Fujino M, Imaizumi S, Karnik SS, Saku K. Clinical and Pharmacotherapeutic Relevance of the Double-Chain Domain of the Angiotensin II Type 1 Receptor Blocker Olmesartan. Clinical and Experimental Hypertension. 2010; 32:129-136.
  • Miura S, Saku K. ReviewEffects of statin and lipoprotein metabolism in heart failure. JOURNAL of CARDIOLOGY. 2010; 55:(3)287-290.
  • Yamaguchi Y, Kumagai K, Nakashima H, Saku K. Long-Term Effects of Box Isolation on Sympathovagal Balance in Atrial Fibrillation. Circulation Journal. 2010; 74(6):1096-1103.
  • Atsushi Ishi, Bo Zhang, Sunao Kaneko, Shinichi Hirose. Positive association between benign familial infantile convulsions and LG14. BRAIN & DEVELOPMENT. 2010; 32(7) :538-43.

2009年

  • Miura S,Fujino M,Karnik SS,Saku K. Angiotensin Progress. Differential pharmacotherapeutic effects of angiotensin II type 1 receptor blockers. Nova Science Publishers. 2009; 221-234.
  • Fukuda Y, Shirai K, Miura S, Ike A, Takamiya Y, Kuwano T, Yanagi D, Mori K, Kubota K, Miller N, Nishikawa H, Zhang B, Saku K. The impact of angulated lesions on angiographic late loss in patients with drug-eluting stent implantation. Journal of Cardiology. 2009; 53:396-401.
  • Sugihara M, Miura S, Takamiya Y, Kiya Y, Arimura T, Iwata A, Kawamura A, Nishikawa H, Uehara Y, Saku K. Safety and efficacy of antihypertensive therapy with add-on angiotensin II type 1 receptor blocker after successful coronary stent implantation. Hypertension Research. 2009; 32:625-630.
  • Takamiya Y, Miura S, Kawamura A, Tanigawa H, Zhang B, Iwaata A, Nishikawa H, Matsuo K, Shirai K, Saku K. Intensive lowering of blood pressure and low-density lipoprotein cholesterol with statin therapy may improve neointimal formation after coronary stenting in patients with coronary artery disease(LOBOCOP). Coron Artery Dis. 2009; 20(4):288-294.
  • Sako H, Miura S, Kumagai K, Saku K. Association between Augmentation Index and Severity of Atheroma or Aortic Stiffness of the Descending Thoracic Aorta by Transesophageal Echocardiography. Circ J. 2009; 73(6):1151-1156.
  • Kiya Y,Miura SI,Imaizumi S,Uehara Y,Matsuo Y,Abe S,Jimi S,Urata H, Rye KA,Saku K. Reconstituted high-density lipoprotein attenuates postinfraction left ventricular remodeling in rats. Atherosclerosis. 2009; 203(1):137-144.
  • MitsutakeR,Miura S, Kawamura A, Saku K. Are Metabolic Factors Associated With Coronary Artery Stenosis on MDCT ?. Circulation Journal. 2009; 73(1):132-138.
  • Miura S,Saku K. Angiotensin II Type 1 Receptor Blocker Combined with Calcium Channel Blocker for the Treatment of Obese Hypertensive Patients. INTERNAL MEDICINE. 2009; 48(1):1-2.
  • Kimura K,Miura S,Iwata A,Sugihara M,Arimura T,Nishikawa H, Kawamura A,Saku K. Association between cardiac function and metabolic factors including adiponectin in patients with acute myocardial infarction. Journal of Cardiology. 2009; 53(1):65-71.
  • Miyachi K,Hankins RW,Uehara Y,Zhang B,Saku K,Homma Y,Shigematu H,MIkoshiba K. A Postmenopausal Patient with Tangier Disease Developing Sjogren's Syndrome. J Rheumatol. 2009; 36(1):208-9.
  • Furuyama S,Uehara Y,Zhang B,Baba Y,Abe S,Iwamoto T, Miura S,Saku K. Genotypic effect of ABCG1 gene promoter-257T>G polymorphism on coronary artery disease severity in Japanese men. J Atheroscler Thromb. 2009; 16;194-200.
  • Kitajima K,Miura S,Matsuo Y,Uehara Y,Saku K. Newly developed PPAR-α agonist (R)-K-13675 inhibits the secretion of inflammatory markers without affecting cell proliferation or tube formation. Atherosclerosis. 2009; 203(1):75-81.
  • Yamashita T,Ogawa S, Sato T, Aizawa Y, Atarashi H, Fujiki A, Inoue H, Ito M, Katoh T, Kobayashi Y, Koretsune Y, Kumagai K, Niwano S, Okazaki O,Okamura K, Saku K, Tanabe T, Origasa H for the J-BAF Investigators. Dose-Response Effects of Bepridil in Patients With Persistent Atrial Fibrillation Monitored With Transtelephonic Electrocardiograms ― A Multicenter, Randomized, Placebo-Controlled, Double-Blind Study (J-BAF Study) ―. Circulation Journal. 2009; 73(6):1020-1027.
  • Mitsutake R, Miura S, Iwata A, Saku K. Aneurysms of right-sided descending aorta associated with right-sided aortic arch detected by 64-multidetector-row Computed Tomography. Intern Med. 2009; 48(7):575-576.
  • Mitsutake R, Miura S, Tanaka T, Matsuo K, Saku K. Coronary artery aneurysm with thrombus evaluated by multi-detector row computed tomography. Intern Med. 2009; 48(5):339-41.
  • Mitsutake R, Miura SI, Zhang B, Saku K. HDL-associated factors provide additional prognostic information for coronary artery disease as determined by multi-detector row computed tomography. Int J Cardiol. 2009; Epub ahead of print.
  • Kimura T, et al (Saku K) J-Cypher Resistry Investigators. Antiplatelet therapy and stent thrombosis after sirolimus-eluting stent implantation. Circulation. 2009; 119(7):987-995.
  • Zhang B, Matsunaga A, Rainwater DL, Miura SI, Noda K, Nishikawa H, Uehara Y, Shirai K, Ogawa M, Saku K. Effects of ROSuvastatin on electronegative LDL as characterized by CapillARY isotachophoresis: The ROSARY study. J Lipid Res. 2009; 50:1832-1841.
  • Miura S,Fujino M,Karnik SS,Saku K. Angiotensin Progress. Differential pharmacotherapeutic effects of angiotensin II type 1 receptor blockers. Nova Science Publishers. 2009; 221-234.
  • Fukuda Y, Shirai K, Miura S, Ike A, Takamiya Y, Kuwano T, Yanagi D, Mori K, Kubota K, Miller N, Nishikawa H, Zhang B, Saku K. The impact of angulated lesions on angiographic late loss in patients with drug-eluting stent implantation. Journal of Cardiology. 2009; 53(3):396-401.
  • Sugihara M, Miura S, Takamiya Y, Kiya Y, Arimura T, Iwata A, Kawamura A, Nishikawa H, Uehara Y, Saku K. Safety and efficacy of antihypertensive therapy with add-on angiotensin II type 1 receptor blocker after successful coronary stent implantation. Hypertension Research. 2009; 32(7):625-630.
  • Takamiya Y, Miura S, Kawamura A, Tanigawa H, Zhang B, Iwaata A, Nishikawa H, Matsuo K, Shirai K, Saku K. Intensive lowering of blood pressure and low-density lipoprotein cholesterol with statin therapy (LOBOCOP) may improve neointimal formation after coronary stenting in patients with coronary artery disease. Coron Artery Dis. 2009; 20(4):288-294.
  • Sako H, Miura S, Kumagai K, Saku K. Association between Augmentation Index and Severity of Atheroma or Aortic Stiffness of the Descending Thoracic Aorta by Transesophageal Echocardiography. Circ J. 2009; 73(6):1151-1156.
  • Piccinillo G, Magri D, Ogawa M, Song J, Chong VJ, Han S, Joung B, Choi EK, Hwang S, Cheng LS, Lin SF, Chen PS. Autonomic Nervous System Activity Measured Directly and QT Interval Variability in Normal and Pacing-Induced Tachycardia Heart Failure Dogs. J Am Coll Cardiol. 2009; 54(9):840-50.
  • Ogawa M, Zhoug S, Tan AY, Fishbein MC, Lin SF, Chen LS, Chen PS. What have we learned about the contribution of autonomic nervous system to human arrhythmia ?. Heart Rhythm. 2009; 6(8Supple):S8-11.
  • Ogawa M, Morita N, Tang L, Karagueuzian HS, Weiss JN, Lin SF, Chen PS. Mechanisms of recurrent ventricular fibrillation in a rabbit model of pacing-induced heart failure. Heart Rhythm. 2009; 6(6):784-92.
  • Piccirillo G, Ogawa M, Song J, Chong VJ, Joung B, Han S, Magri D, Chen LS, Lin SF, Chen PS. Power spectral analysis of heart rate variability and autonomic nervous system activity measured directly in healthy dogs and dogs with tachycardia-induced heart failure. Heart Rhythm. 2009; 6(4):546-52.
  • Arimura T, Mitsutake R, Miura S, Nishikawa H, Kawamura A, Saku K. Acute Myocardial Infarction Associated with Pregnancy Successfully Treated with Percutaneous Coronary Intervention. Internal Medicine. 2009; 48:1383-1386.
  • Qin Y, Yasuda N, Akazawa H, Ito K, Kudo Y, Liao CH, Yamamoto R, Miura S, Saku K, Komuro I. Multivalent ligand-receptor interactions elicit inverse agonist activity of AT1 receptor blockers against stretch-induced AT1 receptor activation. Hypertension Research. 2009; 32(10):875-883.
  • Fukuda Y, Miura S, Zhang B, Iwata A, Kawamura A, Nishikawa H, Shirai K, Saku K. Significance of Urinary Liver-fatty Acid-binding Protein in Cardiac Catheterization in Patients with Coronary Artery Disease. INTERNAL MEDICINE. 2009; 48:1731-1737.
  • Miura S, Saku K. Do Angiotensin-converting Enzyme Inhibitors and Angiotensin II Receptor Blockers Have Similar Effects in the Improvement of Left Ventricular Dysfunction after Myocardial Infarction in Japanese?. INTERNAL MEDICINE. 2009; 48:1929-1930.
  • Kumagai N, Mitsutake R, Miura S, Kawamura A, Takamiya Y, Nishikawa H, Uehara Y, Saku K. Acute colonary syndrome associated with essential thrombocythemia. J Cardiol. 2009; 54(3):485-489.
  • Miura S, Saku K. Do angiotensin II type 1 receptor blockers have molecular effects?. Hypertens Res. 2009; Epub ahead of print.
  • Miura S, Matsuo Y, Kiya Y, Karnic SS, Saku K. Molecular mechanisms of the antagonistic action between AT(1) and AT(2) receptors. Biochem Biophys Res. 2009; Epub ahead of print.
  • Mitsutake R, Miura S, Shiga Y, Iwata A, Saku K. Coronary-pulmonary artery fistula with anomalous vessels arising from the right coronary sinus detected by 64-MDCT. Intern Med. 2009; 48(21):1893-1896.
  • Koike T, Kitajima S, Yu Y, Li Y, Nishijima K, Liu E, Sun H, Waqar AB, Inoue T, Wang Y, Zhang B, Kobayashi J, Morimoto M, Saku K, Watanabe T, Fan J. Expression of human apoAII in transgenic rabbits leads to dyslipidemia: a new model for combined hyperlipidemia. Arterioscler Thromb Vasc Biol. 2009; 29(12):2047-2053.
  • Kumagai N, Mitsutake R, Miura S, Kawamura A, Takamiya Y, Nishikawa H, Uehara Y, Saku K. Acute coronary syndrome associated with essential thrombocythemia. Journal of Cardiology. 2009; 54:485-489.
  • Tanigawa H, Billheimer JT, Tohyama J, Fukui IV, Ng DS, Rothblat GH, Rader DJ. Lecithin:Cholesterol Acyltransferase Expression Has Minimal Effects on Macrophage Reverse Cholesterol Transport In Vivo. Circulation. 2009; 120:160-169.
  • Ogawa M, Tan AY, Song J, Kobayashi K,Fishbein MC,Lin SF,Chen LS,Chen PS. Cryoablation of stellate ganglia and atrial arrhythmia in ambulatory dogs with pacing-induced heart failure. Heart Rhythm. 2009; 6(12):1772-9.
  • Joung B, Ogawa M, Lin SF, Chen PS. The Calcium and voltage Clocks in sinoatrial node automaticity. Korean Circ J. 2009; 39(6):217-22.
  • Bhuiyan MA, Ishiguro M, Hossain M, Nakamura T, Ozaki M, Miura S, Nagatomo T. Binding sites of valsartan, candesartan and losartan with angiotensin II reseptor 1 subtype by molecular modeling. Life Sci. 2009; 85:136-140.
  • Bhuiyan MA, Hossain M, Miura S, Nakamura T, Ozaki M, Nagatomo T. Constitutively active mutant N111G of angiotensin II type 1(AT1) receptor induced homologous internalization through mediation of AT1 -receptor antagonist. J Pharmacol Sci. 2009; 111:227-234.

2008年

  • Miura S,Kiya Y,Kanazawa T,Imaizumi S,Fujino M,Matsuo Y,Karnik S,Saku K. Differential Bonding Interactions of Inverse Agonists of AngiotensinII Type1 Receptor in Stabilizing the Inactive State. Molecular Endocrinology. 2008; 22(1):139-146.
  • Li M,Naqvi N,Yahiro E,Liu K,Powell P,Bradley E,Martin D,Graham R,Dell'Italia L,Husain A. c-Kit Is Required for Cardiomyocyte Terminal Differentiation. Circulation Research. 2008; March 28.
  • Morito N,Inoue Y,Urata M,Yahiro E,Kodama S,Fukuda N,Saito N,Tsuchiya Y,Mihara H,Yamanouchi Y,Saku K,Urata H. Increased carotid artery plaque score is an independent predictor of the presence and severity of coronary artery disease. Journal of Cardiology. 2008; 51(1):25-32.
  • Miura S,Saku K. Do Statins Need to be Prescribed for All Patients with Left Ventricular Dysfunction? INTERNAL MEDICINE. 2008; 47:335-336.
  • Yasuda N,Miura S,Akazawa H,Tanaka T,Qin Y,Kiya Y,Imaizumi S,Fujino M,Ito K,Zou Y,Fukuhara S,Kunimoto S,Fukuzaki K,Sato T,Ge J,Mochizuki N,Nakaya H,Saku K. Conformational switch of angiotensinII type1 receptor underlying mechanical stress-induced activation. EMBO Report. 2008; 9(2):179-186.
  • Mitsutake R,Miura S,Nishikawa H,Saku K. Usefulness of the evaluation of stent fracture by 64-multi-detector row computed tomography. Journal of Cardiology. 2008; 51(2):135-138.
  • Yanagi D,Shirai K,Takamiya Y,Fukuda Y,Kuwano T,Ike A,Mori K,Kubota K,Iwata A,Fujimi K,Miller N,Zhang B,Tsuchiya Y,Urata H,Saku K. Results of provisional stenting with a Sirolimus-eluting stent for bifurcation lesion:Multicenter study in Japan. Journal of Cardiology. 2008; 51(2):89-94.
  • Mitsutake R,Miura S,Sako H,Nishikawa H,Saku K. Usefulness of multi-detector row computed tomography for the management of percutaneous transluminal septal myocardial ablation in patient with hypertrophic obstructive cardiomyopathy. International Journal of Cardiology. 2008; 129(2):e61-63.
  • Inoue Y,Zhang B,Sadamori R,Shirota K,Saku K,Kawarabayashi T. Changes in lipid metabolism in postmenopausal Japanese women using hormone therapy evaluated by capillary isotachophoresis: a pilot study. Menopause. 2008; 15(1):157-163.
  • Uehara Y,Tsuboi Y,Zhang B,Miura S,Baba Y,higuchi MA,Yamada T,Rye KA,Saku K. POPC/apo-A I discs as a potent lipoprotein modulator in Tangier disease. Atherosclerosis. 2008; 197(1):283-289.
  • Sako H,Miura S,Iwata A,Nishikawa H,Kawamura A,Matsuo K,Shirai K,Saku K. Changes in CCR2 Chemokine Receptor Expression and Plasma MCP-1 Concentration after the Implantation of Bare Metal Stents Versus Sirolimus-eluting Stents in Patients with Stable Angina. INTERNAL MEDICINE. 2008; 47(1):7-13.
  • Mitsutake R,Shirai K,Nishikawa H,Saito N,Miura S,Saku K. Calcified Occlusion of the Coronary Arteries in a Young Woman Diagnosed with Kawasaki Disease. INTERNAL MEDICINE. 2008; 47:559-560.
  • Zhang B,Miura S,Yanagi D,Noda K,Nishikawa H,Matsunaga A,Shirai K,Iwata A,Yoshinaga K,Adachi H,Imaizumi T,Saku K. Reduction of charge-modified LDL by statin therapy in patients with CHD or CHD risk factors and elevated LDL-C levels:The SPECIAL Study. ATHEROSCLEROSIS. 2008; 201(2):353-359.
  • Miura S,Matsuo Y,Saku K. Jun N-Terminal Kinase Inhibitor Blocks Angiogenesis by Blocking VEGF Secretion and an MMP Pathway.Journal of Atherosclerosis and Thrombosis. 2008; 15(2):69-74.
  • Imaizumi S,Miura S,Nakamura K,Kiya Y,Uehara Y,Zhang B,Matsuo Y,Urata H,Ideishi M,Rye K,Sata M,Saku K. Antiarrhythmogenic Effect of Reconstituted High-Density Lipoprotein Against Ischemia/Reperfusion in Rats. Journal of the American College of Cardiology. 2008; 51(16):1604-1612.
  • Takamiya Y,Shirai K,Fujino M,Miller N,Tsuchiya Y,Okabe M,Saku K. Purulent pericarditis with salmonella enteritidis in a patient with CD4/CD8 depression. Journal of Cardiology. 2008; 51(3):201-204.
  • Fukuda Y,Shirai K,Takamiya Y,Nathan M,Mito T,Yanagi D, Hida S,Iwata A,Yasuda T,Zhang B,Nishikawa H,Ideishi M,Saku K. Isolated pulmonary arterial stenosis caused by Takayasu's arteritis in an elderly male. Journal of Cardiology. 2008; 51(3):196-200.
  • Miura S,Kawamura A,Saku K. Efficacy and Safety of Drug-eluting Stents in Long-term Follow-up. INTERNAL MEDICINE. 2008; 47:987-988
  • Miura S,Saku K. Angiotensin II Type 1 Receptor Brocker Combined with Hydrochlorothiazide for the Treatment of Hypertension. INTERNAL MEDICINE. 2008;47(13):1163-1164.
  • Bai H,Liu R,Liu Y,Saku K, Liu B. Distribution and effect of apo A-IV genotype on plasma lipid and apolipoprotein levels in a Chinese population. Acta Cardiology. 2008; 63(3):315-322.
  • Uehara Y,Yamada T,Baba Y,Miura S,Abe S,Kitajima K,Higuchi M,Iwamoto T,Saku K. ATP-binding cassette transporter G4 is highly expressed in microglia in Alzheimer's brain. BRAIN RESEARCH. 2008; 1217(2008):239-246.
  • Miura S,Saku K. Beneficial effects of ezetimibe-based therapy in patients with dyslipidemia. Journal of Cardiology. 2008; 52(1):1-6
  • Sako H,Miura S,Saku K. Significance of changes in plasma adiponectin concentration after the implantation of stents in patients with stable angina. Journal of Cardiology. 2008; 52(1):17-23
  • Miura S, Saku K. Ezetimibe, a Selective Inhibitor of the Transport of Cholesterol. INTERNAL MEDICINE. 2008; 47(13):1165-1170.
  • Zhou S, Tan AY, Paz O, Ogawa M, Chou CC, Hayashi H, Nihei M, Fishbein, MC, Chen LS, Lin SF, Chen PS. Antiarrhythmic Effects of Beta3-Adrenergic Receptor Stimulation in a Canine Model of Ventricular Tachycardia.Heart Rhythm. 2008; 5: 289-297.
  • Ogawa M, Lin SF, Weiss JN, Chen PS. Calcium Dynamics and Ventricular Fibrillation. Circ Res.. 2008; 102: e52.
  • Tang L, Hwang GS, Hayashi H, Song J, Ogawa M, Kobayashi K, Joung B, Karagueuzian HS, Chen PS, Lin SF. Intracellular Calcium Dynamics at the Core of Endocardial Stationary Spiral Waves in Langendorff-Perfused Rabbit Hearts. Am J Physiol Heart Circ Physiol. 2008; 295:H297-304.
  • Tan AY, Zhou S, Jung BC, Ogawa M, Chen LS, Fishbein MC, Chen PS. Ectopic Atrial Arrhythmias Arising from Canine Thoracic Veins During In-vivo Stellate Ganglia Stimulation. Am J Physiol Heart Circ Physiol. 2008; 295 : H691-8.
  • Tan AY, Zhou S, Ogawa M, Song J, Chu M, Li H, Fishbein MC, Lin S-F, Chen LS, Chen P-S. Neural Mechanism of Paroxysmal Atrial Fibrillation and Paroxysmal Atrial Tachycardia in Ambulatory Canines. Circulation. 2008; 118:916-25.
  • Yanagi D,Shirai K,Arimura T,Saito N,Mitsutake T,Mitsutake R,Hida S,Iwata A,Nishikawa H,Kawamura A,Miura S,Saku K. Left Ventricular Oozing Rupture following Acute Myocardial Infarction. INTERNAL MEDICINE. 2008; 47:1803-1805
  • Miura S,Saku K. Higher Plasma Levels of Adiponectin in Hemodialysis Patients: Good or Bad? INTERNAL MEDICINE. 2008; 47:1825-1826
  • Miura S,Saku K. Which strategy is more effective for the treatment of cardiovascular disease: high-dose angiotensin II type 1 receptor antagonist monotherarpy or combination therapy? American Journal of Cardiovascular Drugs. 2008; 8(2):88-90.
  • Kuwano T,Miura S,Nishikawa H, Shirai K,Saku K. Venous Thrombosis Associated with a Large Uterine Myoma. INTERNAL MEDICINE. 2008; 47(8):809.
  • Mitsutake R,Miura S,ShigaY,Kawamura A,Saku K. Is Chronic Kidney Disease Associated with Coronary Artery Stenosis or Calcification as Assessed by Multi-detector Row Computed Tomography? INTERNAL MEDICINE. 2008; 47(21):1835-41.
  • Iwata A,Miura S,Mori K,Kawamura A,Nishikawa H,Saku K. Associations between Metabolic Factors and Coronary Plaque Growth or Arterial Remodeling as Assessed by Intravascular Ultrasound in Patients with Stable Angina. Hypertension Research. 2008; 31(10):1879-1886.
  • Zhang B, Matsunaga A, Rainwater DL, Miura SI, Noda K, Nishikawa H, Uehara Y, Shirai K, Ogawa M, Saku K. Effects of ROSuvastatin on electronegative LDL as characterized by CapillARY isotachophoresis: The ROSARY study. J Lipid Res. 2008; Epub ahead of print.
  • Tolle M, Pawlak A, Schuchardt M, Kawamura A, Tietge UJ, Lorkowski S, Keul P, Assmann G, Chun J, Levkau B, van der Giet M, Nofer JR.. HDL-associated lysosphingolipids inhibit NAD(P)H oxidase-dependent monocyte chemoattractant protein-1 production. Arterioscler Thromb Vasc Biol. 2008; 28(8):1542-1548.

2007年

  • Iwata A,Miura S,Imaizumi S,Kiya Y,Nishikawa H,Zhang B,Shimomura H,Saku K. Do Valsartan and Losartan Have the Same Effects in the Treatment of Coronary Artery Disease? Circulation Journal. 2007; 71(1):32-38.
  • Niimura H,Mito T,Matsunaga A,Koga S,Akasu K,Morishige N,Tashiro T,Saku K. Left Ventricular Pseudoaneurysm Following Acute Myocardial Infarction. INTERNAL MEDICINE. 2007; 1221-1223.
  • Okamura K,Miura S,Zhang B,Uehara Y,Matsuo K,Kumagai K,Saku K,.Ratio of LDL-to HDL-Associated Platelet-Activating Factor Acetyihydrolase may be a Marker of Inflammation in Patients With Paroxysmal Atrial Fibrillation. Circulation Journal. 2007;71(2):214-219.
  • Yanagi D,Shirai K,Mori K,Ike A,Costantini O,Costantini R,Nishikawa H,Miller N,Zhang B,Tsuchiya Y,Urata H,Saku K. Possible Predictors of Target Lesion Revascularization After Drug-Eluting Stent Implantation.Journal of Cardiology.2007; 49(2):63-67.
  • Nishio M,Noda K,Matsuzaki M,Satoh T,Morita E,Asada R,Takahira M,Hosoi K,Saku K. pre-Information for Participants in Clinical Trials Provided to Medical Doctors other than the Clinical Investigators as Required by Clause 45 of the Welfare Ministerial Ordinance Number28 of 27 March 1997. 2007; 34(1):23-28.
  • Zhang B,Bottcher A,Imaizumi S,Noda K,Schmitz G,Saku K. Relation between charge-based apolipoprotein B-containing lipoprotein subfractions and remnant-like particle cholesterol levels. ATHEROSCLEROSIS. 2007; 191(1):153-161.
  • Uehara Y,Miura S,Eckardstein A,Abe S,Fujii A,Matsuo Y,Rust S,Lorkowski S,Assmann G,Yamada T,Saku K. Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1(ABCG1) and ABCA1 genes via an LXR/RXR responsive element. ATHEROSCLEROSIS. 2007; 191:11-21.
  • Zhang B,Saku K. Control of matrix effects in the analysis of urinary F2-isoprostanes using novel multidimensional solid-phase extraction and LC-MS/MS. Journal of Lipid Research. 2007; 48(3):733-744.
  • Miura S,Saku K. Therapies for Raising High-density Lipoprotein Cholesterol. INTERNAL MEDICINE. 2007; 46(7):339-340.
  • Matsunaga A,Arishima H,Niimura H,Zhang B,Uehara Y,Ohwaki K,Morita M,Hayashida K,Saku K. Strong Linkage Disequilibrium and Association of-1131T>C and c.553G>T Polymorphisms of the Apolipoprotein A5 Gene With Hypertriglyceridemia in a Japanese Population. Circulation Journal. 2007; 71(5):746-752.
  • Sakai T,Saku K. A health-economic evalution of aspirin: primary prevention and cardiovascular disease. INTERNAL MEDICINE. 2007; 46(8):431-433.
  • Zhang B,Uehara Y,Hida S,Miura S,Rainwater D,Segawa M,Kumagai K,Rye K,Saku K. Effects of apoA-I/phosphatidylcholine discs on charge-based LDL subfractions as characterized by capillary isotachophoresis. J Lipid Res. 2007; 48:1175-1189.
  • Sumi M,Miura S,Rye K,Toya N,Kanaoka Y,Yanaga K,Ohki T,Saku K,Nagai R. Reconstituted high-density lipoprotein stimulates differentiation of endothelial progenitor cells and enhances ischemia-induced angiogenesis, Arterioscler Thromb Vasc Biol. 2007; 27(4):813-818.
  • Matsuo Y,Miura S,Kawamura A,Uehara Y,Rye K,Saku K. Newly developed reconstituted high-density lipoprotein containing sphingosine-1-phosphate induces endothelial tube formation. Atherosclerosis. 2007; 194(1):159-168.
  • Iwata A,Miura S,Shirai K,Kawamura A,Tomita S,Matsuo Y,Zhang B,Nishikawa H,Kumagai K,Matsuo K,Saku K. Lower Level of Low-density Lipoprotein Cholesterol by Statin Prevents Progression of Coronary Restenosis after successful Stenting in Acute Myocardial Infarction. INTERNAL MEDICINE. 2007; 45(15):885-890.
  • Kumagai K. Upstream Therapy for Atrial Fibrillation. Circulation Journal. 2007; 71(A):75-81.
  • Takamiya Y,Miura S,Sako H,Shirai K,Morishige N,Tashiro T,Saku K. Pseudoaneurysm of the Mitral-Aortic Intervalvular Fibrosa Following Infective Endocarditis in a Patient With Acute Heart Failure:A Case Report. Journal of Cardiology. 2007; 49(6):353-356.
  • Mitsutake R,Miura S,Okamura K,Niimura H,Kawamura A,Saku K. Successful Intensive Lipid-lowering Therapy Using Atorvastatin Stabilizes Coronary Artery Plaque as Assessed by Multi-detector Row Computed Tomography. INTERNAL MEDICINE. 2007; 46(12):859-863.
  • Yamaguchi Y,Tsugawa H,Fujioka N,Kaseno K,Kitayama M,Kajinami K. Role of a Novel Conduction Pattern Around the Coronary Sinus in Cavotricuspid Isthmus Dependent Right Atrial Flutter. Journal of Cardiology. 2007; 50(1):1-10.
  • Miura S,Saku K. Regulation of Angiogenesis and Angiogenic Factors by Cardiovascular Medications. Current Pharmaceutical Design. 2007; 13(20):2113-2117.
  • Miura S,Saku K. Do all angiotensinII type1 recepter blockers have the same beneficial effects? British Journal of Pharmacology. 2007; 151(7):912-913.
  • Saku K. Circulation Journal Editorial Bosrd. Circulation Journal. 2007.
  • Mitsutake R,Miura S,Nishikawa H,Saku K. Left Main Trunk Coronary Stenosis in an Angina Patient With Low Coronary Risk Factors Assessed by Multi-Detector Row Computed Tomography. Journal of Cardiology. 2007; 50(3):219-221.
  • Iwata A,Miura S,Imaizumi S,Zhang B,Saku K. Measurement of Atherosclerotic Plaque Volume in Hyperlipidemic Rabbit Aorta by Intravascular Ultrasound. Journal of CARDIOLOGY . 2007; 50(4):229-234.
  • Hagiwara M,Yamagata K,Matsunaga T,Arakawa Y,Usui J,Shimizu Y,Aita K,Nagata M,Koyama A,Zhang B,Mastunaga A,Saku K,Saito T. A novel apolipoprotein E mutation,ApoE Tsukuba(Arg114Cys) in lipoprotein glomerulopathy. Nephrol Dial Transplant. 2007; 23(1):381-384.
  • Murakami K,Uehara Y,Abe T,Inoue Y,Ideishi M,Saku K,Urata H. Positive Correlation Between Chymase-Like Angiotensin II-Forming Activity in Mononuclear Cells and Serum Cholesterol Level. Journal of Cardiology. 2007; 50(5):291-298.
  • Nakashima H,Kumagai K. Reverse-Remodeling Effects of AngiotensinII Type1 Receptor Blocker in a Canine Atrial Fibrillation Model. Circulation Journal. 2007; 71(12):1977-1982.
  • Muraoka S,Mitsutake C,Takashima H,Nakashima H,Yasuda T,Matsumoto N,Kumagai K,Saku K. Efficacy and Safety of Catheter Ablation for Persistent or Permanent Atrial Fibrillation. Journal of Arrhythmia. 2007; 23(3):229-235.
  • Kawamura A,Baitsch D,Telgmann R,Feuerborn R,Weissen G,Hagedorn C,Saku K,Herrmann B,Eckardstein,Assmann G,Nofer J. Apolipoprotein E Interrupts Interleukin-1β Signaling in Vascular Smooth Muscle Cells. Arterioscler Thromb Vasc Biol. 2007; 27(7):1610-1617.
  • Sakai T. Assesssment of DPC implemented to improve the cost-effectiveness,the foundation of health insurance association,and the quality of health care. INTERNAL MEDICINE. 2007; 1-76.
  • Mitsutake R,Miura S,Saku K. Association between Coronary Artery Calcification Score as Assessed by Multi-detector Row Computed Tomography and Upstroke Time of Pulse Wave. INTERNAL MEDICINE. 2007; 46(22):1833-1836.
  • Ogawa M,Kumagai K,Vakulenko T,Yasuda T,Siegerman C,Garfinkel A,Chen PS,Saku K. Reduction of P-wave duration and successful pulmonary vein isolation in patients with atrial fibrillation. Journal of Cardiovascular Electrophysiol. 2007; 18(9):931-938.
  • Zhang B,Uehara Y,Hida S,Rainwater DL,Segawa M,Kumagai K,Rye KA,Saku K. Effects of reconstituted HDL on charge-based LDL subfractions as characterized by capillary isotachophoresis. Journal of Lipid Research. 2007; 48(5):1175-1189.
  • Senanayake P,Drazba J,Shadrach K,Milsted A,Rungger-Brandle E,Nihiyama K,Miura S,Karnik SS,Sears JE,Hollyfield JG. AngiotensinII and Its Receptor Subtypes in the Human Retina. Invest Ophtalmol Vis Sci. 2007; 48:3301-3311.
  • Miura S,Saku K. Reconstituted or recombinant high-density Iipoprotein is a therapeutic strategy for the treatment of atherisclerotic cardiovascular diseases. Fukuoka University. 2007; 4-7.
  • Miura S,Saku K. Treatment of cardiovascular disease using angiotensinII type 1 receptor blocker:a current perspective. Fukuoka University. 2007; 8-11.
  • Saku K. Molecular Mechanisms in Atherosclerotic Cardiovascular Disease,and the Development of New Therapeutic Strategies for Atherosclerosis. 2007.
  • Kumagai K,Muraoka S,Mitsutake C,Takashima H,Nakashima H. A New Approach Complete Isolation of the Posterior Left Atrium Including Pulmonary Veins for Atrial Fibrillation. Journal of Cardiovascular Electrophysiology. 2007; 18(10):1047-1052.
  • Saku K. Internal Medicine2007SanDiego,CA. Japan Chapter GOVERNOR'S NEWSLETTER. 2007; 6.
  • Ogawa MZhou S,Tan AY,Song J,Gholmieh G,Fishbein MC,Luo H,Siegel RJKarageuzian HS,Chen LS,Lin SF,Chen PS. Left Stellate Ganglion and Vagal Nerve Activity and Cardiac Arrhythmias in Ambulatory Dogs with Pacing-Induced Congestive Heart Failure. J Am Coll Cardiol. 2007; 24;50:335-343.
  • Ogawa M, Kumagai K, Vakulenko M, Yasuda T, Siegerman C ,Garfinkel A, Chen PS, Saku K. Reduction of P-wave Duration and Successful Pulmonary Vein Isolation in Patients With Atrial Fibrill.ation. J Cardiovasc Electrophysiol. 2007; 18:931-938.

2006年

  • Niimura H, Mito T, Matsunaga A, Koga S, Akasu K, Morishige N, Tashiro T, Saku K. Left ventricular pseudoaneurysm following acute myocardial infarction. Intern Med. 2006;45(21):1221-3.
  • Matsuo Y, Miura SI, Kawamura A, Uehara Y, Rye KA, Saku K.. Newly developed reconstituted high-density lipoprotein containing sphingosine-1-phosphate induces endothelial tube formation. Atherosclerosis. 2006 Nov 20.
  • Kumagai K, Nakashima H, Tojo H, Yasuda T, Noguchi H, Matsumoto N, Ogawa M, Saku K. Pilsicainide for atrial fibrillation. Drugs. 2006;66(16):2067-73. Review.
  • Kiya Y, Miura S, Zhang B, Urata H, Saku K. Effect of levothyroxine on total lipid profiles as assessed by analytical capillary isotachophoresis in a patient with hypothyroidism. Endocr J. 2006;53(6):865-8.
  • Iwata A, Miura S, Shirai K, Kawamura A, Tomita S, Matsuo Y, Zhang B, Nishikawa H, Kumagai K, Matsuo K, Saku K.. Lower level of low-density lipoprotein cholesterol by statin prevents progression of coronary restenosis after successful stenting in acute myocardial infarction. Intern Med. 2006;45(15):885-90.
  • Mitsutake R, Niimura H, Miura S, Zhang B, Iwata A, Nishikawa H, Kawamura A, Kumagai K, Shirai K, Matsunaga A, Saku K.. Clinical significance of the coronary calcification score by multidetector row computed tomography for the evaluation of coronary stenosis in Japanese patients. Circ J. 2006;70(9):1122-7.
  • Kamochi H, Yamanouchi Y, Saku K.. Effects of angiotensin converting enzyme inhibitor and angiotensin II receptor blocker on ventricular defibrillation threshold. PacingClin Electrophysiol. 2006 29(7):747-52.
  • Shirai K, Saku K. Treatment strategy for patients with acute myocardial infarction.Intern Med. 2006;45(13):807-8.
  • Tanigawa H, Miura S, Matsuo Y, Fujino M, Sawamura T, Saku K. Dominant-negative lox-1 blocks homodimerization of wild-type lox-1-induced cell proliferation through extracellular signal regulated kinase 1/2 activation. Hypertension. 2006;48(2):294-300.
  • Zhang B, Katafuchi R, Arishima H, Matsunaga A, Rye KA, Saku K.. Effects of atorvastatin and apoA-I/phosphatidylcholine discs on triglyceride-rich lipoprotein subfractions as characterized by capillary isotachophoresis. Clin Chim Acta. 2006;373(1-2):55-61.
  • Imaizumi S, Miura S, Nishikawa H, Iwata A, Zhang B, Kawamura A, Tsuchiya Y, Kumagai K, Matsuo K, Saku K. Angiotensin II type 1 receptor blockers do not promote coronary collateral circulation in patients with coronary artery disease. Hypertens Res. 2006;29(3):135-41.
  • Uehara Y, Miura S, von Eckardstein A, Abe S, Fujii A, Matsuo Y, Rust S, Lorkowski S, Assmann G, Yamada T, Saku K Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsive element. Atherosclerosis. 2007;191(1):11-21.
  • Miura S, Fujino M, Hanzawa H, Kiya Y, Imaizumi S, Matsuo Y, Tomita S, Uehara Y, Karnik SS, Yanagisawa H, Koike H, Komuro I, Saku. Molecular mechanism underlying inverse agonist of angiotensin II type 1 receptor. J Biol Chem. 2006;281(28):19288-95.
  • Zhang B, Bottcher A, Imaizumi S, Noda K, Schmitz G, Saku K. Relation between charge-based apolipoprotein B-containing lipoprotein subfractions and remnant-like particle cholesterol levels. Atherosclerosis. 2007;191(1):153-61.
  • Iwata A, Miura S, Nishikawa H, Kawamura A, Matsuo Y, Sako H, Kumagai K, Matsuo K, Saku K Significance of combined angiotensin II receptor blocker and carvedilol therapy in patients with congestive heart failure and arginine variant. J Cardiol. 2006;47(1):1-7.
  • Tanigawa H, Miura S, Zhang B, Uehara Y, Matsuo Y, Fujino M, Sawamura T, Saku K. Low-density lipoprotein oxidized to various degrees activates ERK1/2 through Lox-1. Atherosclerosis. 2006;188(2):245-50.
  • Kumagai K, Noguchi H, Ogawa M, Nakashima H, Zhang B, Miura S, Saku K. New aproach to pulmonary vein isolation for atrial fibrillation using a multielectrode basket catheter. Circ J. 2006;70(1):88-93.
  • Tsuji E, Tsuji Y, Fujiwara T, Ogata S, Tsukamoto K, Saku K.Splicing variant of Cdc42 interacting protein-4 disrupts beta-catenin-mediated cell-cell adhesion: expression and function in renal cell carcinoma. Biochem Biophys Res Commun. 2006;339(4):1083-8.
  • Zhang B, Miura S, Fan P, Kumagai K, Takeuchi K, Uehara Y, McMahon M, Rye KA, Saku K. ApoA-I/phosphatidylcholine discs remodels fast-migrating HDL into slow-migrating HDL as characterized by capillary isotachophoresis. Atherosclerosis. 2006;18:95-101.
  • Fujino M, Miura S, Matsuo Y, Tanigawa H, Kawamura A, Saku K. Pitavastatin-induced downregulation of CCR2 and CCR5 in monocytes is associated with the arrest of cell-cycle in S phase. Atherosclerosis. 2006;187(2):301-8.
  • Zhang B, Maeda N, Okada K, Tatsukawa M, Sawayama Y, Matsunaga A, Kumagai K, Miura S, Nagao T, Hayashi J, Saku K Association between fast-migrating low-density lipoprotein subfraction as characterized by capillary isotachophoresis and intima-media thickness of carotid artery. Atherosclerosis. 2006;187(1):205-12.

2005年

  • Nishikawa H, Miura S, Shimomura H, Kawamura A, Tsujita K, Shirai K, Matsuo K, Arai H, Saku K. Effect of statin on restenosis after radius stent implantation in patients with acute coronary syndrome. J Atheroscler Thromb. 2005;12:302-6.
  • Zhang B, Shono N, Fan P, Ando S, Xu H, Jimi S, Miura S, Kumagai K, Win KM, Matsunaga A, Iwasaski H, Saku K. Histochemical characteristics of soleus muscle in angiotensin-converting enzyme gene knockout mice. Hypertens Res. 2005;28:681-8.
  • Takeuchi K, Ideishi M, Tashiro T, Morishige N, Yamada T, Saku K, Urata H. Higher small arterial elasticity in hypertensive patients treated with angiotensin II receptor blockers. Hypertens Res. 2005;28:639-44.
  • Tanigawa H, Miura S, Zhang B, Uehara Y, Matsuo Y, Fujino M, Sawamura T, Saku K. Low-density lipoprotein oxidized to various degrees activates ERK1/2 through Lox-1. Atherosclerosis. 2005 (in press)
  • Noda K, Zhang B, Uehara Y, Miura S, Matsunaga A, Saku K. Potent capillary isotachophoresis (cITP) for analyzing a marker of coronary heart disease risk and electronegative low-density lipoprotein (LDL) in small dense LDL fraction. Circ J. 2005;69:1568-70.
  • Tojo H, Kumagai K, Noguchi H, Ogawa M, Yasuda T, Nakashima H, Zhang B, Miura S, Saku K. Hybrid therapy with pilsicainide and pulmonary vein isolation for atrial fibrillation. Circ J. 2005;69:1503-7.
  • Kumagai K, Ogawa M, Noguchi H, Nakashima H, Zhang B, Miura S, Saku K. Comparison of 2 mapping strategies for pulmonary vein isolation. Circ J. 2005;69:1496-502.
  • Zhang B, Miura S, Fan P, Kumagai K, Takeuchi K, Uehara Y, McMahon M, Rye KA, Saku K. ApoA-I/phosphatidylcholine discs remodels fast-migrating HDL into slow-migrating HDL as characterized by capillary isotachophoresis. Atherosclerosis. 2005 (in press)
  • Fujino M, Miura S, Matsuo Y, Tanigawa H, Kawamura A, Saku K. Pitavastatin-induced downregulation of CCR2 and CCR5 in monocytes is associated with the arrest of cell-cycle in S phase. Atherosclerosis. 2005 (in press)
  • Zhang B, Maeda N, Okada K, Tatsukawa M, Sawayama Y, Matsunaga A, Kumagai K, Miura S, Nagao T, Hayashi J, Saku K. Association between fast-migrating low-density lipoprotein subfraction as characterized by capillary isotachophoresis and intima-media thickness of carotid artery. Atherosclerosis. 2005 (in press)
  • Miura S, Matsuo Y, Kawamura A, Saku K. JTT-705 blocks cell proliferation and angiogenesis through p38 kinase/p27(kip1) and Ras/p21(waf1) pathways. Atherosclerosis. 2005;182:267-75.
  • Zhang B, Fan P, Shimoji E, Itabe H, Miura SI, Uehara Y, Matsunaga A, Saku K. Modulating effects of cholesterol feeding and simvastatin treatment on platelet-activating factor acetylhydrolase activity and lysophosphatidylcholine concentration. Atherosclerosis. (in press)
  • Zhang B, Kaneshi T, Ohta T, Saku K. Relation between insulin resistance and fast-migrating LDL subfraction as characterized by capillary isotachophoresis. J Lipid Res. 2005;46:2265-77
  • Miura S, Fujino M, Matsuo Y, Tanigawa H, Saku K. Nifedipine-induced vascular endothelial growth factor secretion from coronary smooth muscle cells promotes endothelial tube formation via the kinase insert domain-containing receptor/fetal liver kinase-1/NO pathway. Hypertens Res. 2005;28:147-53.
  • Fujino M, Miura S, Tanigawa H, Matsuo Y, Saku K Counteracting effects of high density lipoprotein-cholesterol subfractions on statin-induced growth arrest. Cardiovasc Drugs Ther. 2005;19:113-8.
  • Ogawa M, Kumagai K, Yamanouchi Y, Saku K. Spontaneous onset of ventricular fibrillation in Brugada syndrome with J wave and ST-segment elevation in the inferior leads. Heart Rhythm. 2005;2:97-9.
  • Nishikawa H, Miura S, Shimomura H, Tsujita K, Okamura K, Zhang B, Iwata A, Shirai K, Matsuo K, Arai H, Saku K. Combined treatment with statin and angiotensin-receptor blocker after stenting as a useful strategy for prevention of coronary restenosis. J Cardiol. 2005;45:107-13.
  • Miura S, Karnik SS, Saku K. Constitutively active homo-oligomeric angiotensin II type 2 receptor induces cell signaling independent of receptor conformation and ligand stimulation. J Biol Chem. 2005;280:18237-44.
  • Miura S, Emoto M, Matsuo Y, Kawarabayashi T, Saku K. The combination of Jun N-terminal kinase inhibitor and TNP-470 blocks carcinosarcoma-induced endothelial cell tube formation in a synergistic manner. Cancer Lett. 2005;220:49-55.
  • Zhang B, Noda K, Matsunaga A, Kumagai K, Saku K. A comparative crossover study of the effects of fluvastatin and pravastatin (FP-COS) on circulating autoantibodies to oxidized LDL in patients with hypercholesterolemia. J Atheroscler Thromb. 2005;12:41-7. Noguchi H, Kumagai K, Yasuda T, Ogawa M, Tojo H, Saku K. Conduction recovery after pulmonary vein isolation for atrial fibrillation. Circ J. 2005;69:65-8.
  • Zhang B, Tomura H, Kuwabara A, Kimura T, Miura S, Noda K, Okajima F, Saku K. Correlation of high density lipoprotein (HDL)-associated sphingosine 1-phosphate with serum levels of HDL-cholesterol and apolipoproteins. Atherosclerosis. 2005;178:199-205.

2004年

  • Kawamura A, Miura S, Murayama T, Iwata A, Zhang B, Nishikawa H, Tsuchiya Y, Matsuo K, Tsuji E, Saku K. Increased Expression of Monocyte CD11a and Intracellular Adhesion Molecule-1 in Patients With Initial Atherosclerotic Coronary Stenosis. Circ J. 68:6-10. 2004
  • Miura S, Emoto M, Matsuo Y, Kawarabayashi T, Saku K. Carcinosarcoma-induced endothelial cells tube formation through KDR/Flk-1 is blocked by TNP-470. Cancer Lett. 203:45-50. 2004
  • Nishikawa H,Miura S,Zhang B,Shimomura H,Arai H,Tsuchiya Y,Matsuo K,Saku K. Statins Induce the Regression of Left Ventricular Mass in Patients With Angina. Circ J. 68:121-125. 2004
  • Fukuma G, Oguni H,Shirasaka Y,Watanabe K,Miyajima T,Yasumoto S,Ohfu M,Inoue T,Watanachai A,Kira R,Matsuo M,Muranaka H,Sofue F,Zhang B,Kaneko S,Mitsudome A,Hirose S. Mutations of Neuronal Voltage-gated Na+Channel α1 Subunit Gene SCN1A in Core Severe Myoclonic Epilepsy in Infancy(SMEI)and in Borderline SMEI(SMEB). Epilepsia. 45:140-148. 2004
  • Ikewaki K,Matsunaga A,Han H,Watanabe H,Endo A,Tohyama J,Kuno M,Mogi J,Sugimoto K,Tada N,Sasaki J,Mochizuki S. A novel two nucleotide deletion in the apolipoprotein A-1 gene,apo A-1 Shinbashi,associated with high density lipoprotein deficiency,corneal opacities,planar xanthomas,and premature coronary artery disease. Atherosclerosis. 172:39-45.2004
  • Zhang B,Bai H,Liu R,Kumagai K,Itabe H,Takano T,Saku K. Serum high-density lipoprotein-cholesterol levels modify the association between plasma levels of oxidatively modified low-density lipoprotein and coronary artery disease in men. Metabolism. 53:423-429. 2004
  • Shimoji E, Zhang B, Fan P, Saku K. Inhibition of cholesteryl ester transfer protein increases serum apolipoprotein(apo) A-II levels by increasing the synthesis of apo A-Ⅰin rabbits. Atherosclerosis. 172:247-257. 2004
  • Noguchi H, Kumagai K, Tohjoh H, Yasuda T, Saku K. Effect of Bachmann's bundle pacing on atrial fibrillation:electrophysiologic assessment. Clin Cardiol. 27:50-53. 2004
  • Zhang B, Tanaka H, Saku K. Simple and rapid detection of uncoupling protein-2 -866G/A polymorphism by mutagenically separated polymerase chain reaction. Clinica Chimica Acta. 344:205-210. 2004
  • Washio M, Hayashi R, Fukuoka Heart Study Group(include Shirai K, Nii T, Ideishi M, Arakawa K, Handa K, Takada K, Kawano T, Doi Y, Mori T, Oda S, Hiroki T, Miyawaki R, Fujino M, Fukuda K, Kanaya H, Kato Y, Ohga M, Sata T, Tashiro T). Past History of Obesity (Overweight by WHO Criteria) Is Associated with an Increased Risk of Nonfatal Acute Myocardial Infaction -A Case-Control Study in Japan-. Circ J. 68:41-46. 2004
  • Lansky A J, Mehran R, Dangas G, Cristea E, Shirai K, Costa R, Costantini C O, Tsuchiya Y, Carlier S, Mintz G S, Cottin Y, Stone G W, Moses J W, Leon M B. Comparison of Differences in Outcome after Percutaneous Coronary Intervention in Men-vs-Women Less Than 40 Years of Age. Am J Cardiol. 93:916-919. 2004
  • Shirai K, Lansky A J, Mehran R, Dangas G, Costantini C O, Fahy M, Slack S, Mintz G S, Stone G W, Leon M B. Minimlly Invasive Coronary Artery Bypass Grafting versus Stenting for Patients with Proximal Left Anterior Descending Coronary Artery Disease. Am J Cardiol. 93:959-962. 2004
  • Kawamura A, Miura S, Murayama T, Iwata A, Nishikawa H, Matsuo Y, Tsuchiya Y, Matsuo K, Tsuji E, Saku K. Changes in the Expression of Leukocyte Adhesion Molecules Throughout the Acute Phase of Myocardial Infarction. Journal of Atherosclerosis and Thrombosis. 11:29-34. 2004
  • Miida T, Zhang B, Obayashi K, Seino U, Zhu Y, Ito T, Nakamura Y, Okada M, Saku K. T13M mutation of lecithin-cholesterol acyltransferase gene causes fish-eye disease. Clinica Chimica Acta. 343:201-8. 2004
  • Shirai K, Saku K. Percutaneous Coronary Intervention for Small Caliber Proximal Coronary Artery Vessels : To Stent or Not to Stent? Med Bull Fukuoka Univ. 31:67-71. 2004
  • Kawano Y, Nagamine K, Arikado S, Nagashima F, Aridome K, Nishino T, Harasawa I, Hamada T, Matsuki H, Hirose N, Ogawa M, Kimura M. Effusive Constrictive Tuberculous Pericarditis -Report of a Case. Med. Bull. Fukuoka Univ. 31:117-123. 2004
  • Kumagai K, Ogawa M, Noguchi H, Yasuda T, Nakashima H, Saku K. Electrophysiologic Properties of Pulmonary Veins Assessed Using a Multielectrode Basket Catheter. Journal of the American College of Cardiology. 43:2281-9. 2004
  • Miura s, Matsuo Y, Saku K. Simvastatin suppresses coronary artery endothelial tube formation by disrupting Ras/Raf/ERK signaling. Atherosclerosis. 175:235-243. 2004
  • Niimura H, Matsunaga A, Kumagai K, Ohwaki K, Ogawa M, Noguchi H, Yonemura K, Saku K.Genetic Analysis of Brugada Syndrome in Western Japan-Two Novel Mutations-. Circ J. 68(8):740-746. 2004
  • Yasuda T, Kumagai K, Ogawa M, Noguchi H, Tojo H, Matsumoto N, Saku K. Predictors of Successful Catheter Ablation for Atrial Fibrillation Using the Pulmonary Vein Isolation Technique. J Cardiol 44(2):53-58. 2004
  • FanP, ZhangB, KurokiS, SakuK. Pitavastatin, a Potent Hydroxymethylglutaryl Coenzyme a Reductase Inhibitor, Increases Cholesterol 7a-Hydroxylase Gene Expression in HepG2 Cells. Circ J 68:1061-1066. 2004.11
  • Ogawa M, Miyoshi K, Morito N, Kodama S, Yahiro E, Fujimi K, Ohta T, Mihara H, Yamanouchi Y, Urata H, Hiroki T, Saku K. Successful catheter ablation of ventricular tachycardia originating from the idiopathic saccular apical left ventricular aneurysm. Int J Cardiol. 93(2-3):343-46. 2004
  • Morito N, Ogawa M, Matsuo S, Mihara H, Miyoshi K, Yahiro E, Fujimi K, Ohta T, Kodama S, Yamanouchi Y, Urata H, Hiroki T, Saku K. Atrial septal defect in apical hypertrophic cardiomyopathy associated with coronary spasm. Int J Cardiol. 93:339-342. 2004
  • Okura Y, Hayashi K, Shingu T, Kajiyama G, Nakashima Y, Saku K. Diagnostic evaluation of acute pancreatitis in two patients with hypertriglyceridemia. World Journal of Gastroenterology. 10:3691-3695. 2004
  • Ogawa M, Kumagai K, Yamaouchi Y,S aku K. Spontaneous onset of ventricular fibrillation in Brugada syndrome with J wave and ST-segment elevation in the inferior leads. Heart Rhythm Society. 97-99. 2004
  • Zhang B, Fan P, Shimoji E, Huali Xu, Takeuchi K, Bian C, Saku K. Inhibition of Cholesteryl Ester Transfer Protein Activity by JTT-705 Increases Apolipoprotein E-Containing High-Density Lipoprotein and Favorably Affects the Function and Enzyme Composition of High-Density Lipoprotein in Rabbits. Arterioscler Thromb Vasc Biol. 1910-1915. 2004
  • Kumagai K,Tojo H, Noguchi H, Yasuda T, Ogawa M, Nakashima H, Zhang B, Saku K. Effects of the Na+Channel Blocker Pilsicainide on the Electrophysiologic Properties of Pulmonary Veins in Patients with Atrial Fibrillation. J Cardiovasc Electrophysiol. 15:1396-1401. 2004
  • Okura Y, Takao M, Zhang B, Nakashima H, Saku K. Cardiovascular Risk Factor Profiles and Endothelial Function in Coronary Artery Disease Patients Treated with Statins. Hypertens Res. 27:723-729. 2004
  • Miura S, Zhang B, Matsuo Y, Saku K ,Karnik SS. Activation of Extracellular Signal-Activated Kinaseby Angiotensin II-Induced Gq-Independent Epidermal Growth Factor Receptor Transactivation. Hypertens Res. 27:765-770.2004
  • Miura S, Yamaguchi Y, Urata H, Himeshima Y, Otsuka N, Tomita S, Yamatsu K, Nishida S, Saku K. Efficacy of a Multicomponent Program(Patient-Centered Assessment and Counseling for Exercise plus Nutrition [PACE+Japan])for Lifestyle Modification in Patients with Essential Hypertension. Hypertens Res. 27:859-964.2004
  • Kumagai K, Nakashima H, Saku K. The HMG-CoA reductase inhibitor atorvaststin prevents atrial fibrillation by inhibiting inflammation in a canine sterile pericarditis model. Cardiovascular Research. 62:105-111. 2004
  • Kumagai K, Ogawa M, Noguchi H, Yasuda T, Nakashima H, Saku K. Elwctrophysiologic Properties of Pulmonary Veins Assessed Using a Muultielectrode Basket Catheter. Journal of the Americann College of Cardiology. 43:2281-2289. 2004
  • Miura S, Fujino M, Matsuo Y, Tanigawa H, Saku K. Nifedipine-Induced Vascular Endothelial Growth Factor Secretion from Coronary Smoot Muscle Cells Promotes Endothelial Tube Formation via the Kinase Insert Domain-Containing Receptor/Fetal Kinase -1/NO Pathway. Hypertens Res. 28:147-153. 2004

2003年

  • Hoshino F,Urata H,Inoue Y,Saito Y,Yahiro E,Ideishi M, Arakawa K,Saku K. Chymase Inhibitor Improves Survival in Hamsters with Myocardial Infarction. Journal of Cardiovascular Pharmacology. 41:S11-S18. 2003
  • Noda K, Takeuchi K, Tashiro T, Kimura M, Saku K. Impaired Bradykinin-mediated Vascular Function is Associated with Coronary Atherosclerosis in Radial and Internal Mammary Arteries from CABG Patients. Med. Bull. Fukuoka Univ. 30:17-28. 2003
  • Miura S, Matsuo Y, Saku K. Transactivation of KDR/Flk-1 by the B2 Receptor Induces Tube Formation in Human Coronary Endothelial Cells. Hypertension. 41:1118-1123. 2003
  • Yahiro E,Ideishi M,Wang X L,Urata H,Kumagai K,Arakawa K,Saku K. Reperfusion-Induced Arrhythmias are Suppressed by Inhibition of the Angiotensin II type 1 Receptor. Cardiology. 99:61-67. 2003
  • Miura S, Fujino M, Matsuo Y, Kawamura A, Tanigawa H, Nishikawa H, Saku K.High Density Lipoprotein-Induced Angiogenesis Requires the Activation of Ras/MAP Kinase in Human Coronary Artery Endothelial Cells. Arterioscler Thromb Vasc Biol. 23:802-808. 2003
  • Miura S, Nishikawa H, Zhang B, Matsuo Y, Kawamura A, Tsuchiya Y, Matsuo K, Saku K. Angiotensin-Converting Enzyme Inhibitor Promotes Coronary Collateral Circulation in Patients With Coronary Artery Disease. Circ J 67:535-538. 2003
  • Kumagai K, Nakashima H, Urata H, Gondo N, Arakawa K, Saku K. Effects of Angiotensin II Type1 Receptor Antagonist on Electrical and Structural Remodeling in Atrial Fibrillation. J American College of Cardiology. 41:2197-2204. 2003
  • Okura Y, Hayashi K, Shingu T, Kuga Y, Nomura S, Kajiyama G, Nakashima Y, Saku K. Angiotensin-converting enzyme insertion / deletion genotype is associated with the activities of plasma coagulation factor X and X independent of triglyceride metabolism. Coronary Artery Disease. 14:285-291. 2003
  • Zhang B, Sakai T, Noda K, Kiyonaga A, Tanaka H, Shindo M, Saku K. Multivariate Analysis of the Prognostic Determinants of the Depressor Response to Exercise Therapy in Patients With Essential Hypertension. Circ J 67:579-584. 2003
  • Miura S, Tanigawa H, Matsuo Y, Fujino M, Kawamura A, Saku K. Ras/Raf1-dependent signal in sphingosine-1-phosphate-induced tube formation in human coronary artery endothelial cells. Biochem Bioph Res Co. 306:924-929. 2003
  • Kumagai K, Nakashima H, Saku K. Elevated C-Reactive Protein and Maintenance of Atrial Fibrillation. Clinical Cardiac Pacing and Electrophysiology. 427-432. 2003
  • Zhang B, Noda K, Saku K. Effect of Atorvastatin on Total Lipid Profiles Assessed by Analytical Capillary Isotachophoresis. Cardiology. 99:211-213. 2003
  • Shirai K, Lansky A J, Mintz G S,Costantini C O, Cristea E, Fahy M, Vandertie L, Yeung A, Raizner A E, Waksman R, Leon M B. Feasibility and Efficacy of Tandem Positioning on Angiographic and Clinical Outcomes in the Intimal Hyperplasia Inhibition With Beta In-Stent Trial. Am J Cardiol 91:1113-1115. 2003
  • Costantini C O, Lansky A J, Mintz G S, Shirai K, Teirstein P S, Stone G, Vandertie L, Proctor B, Fahy M, Yeung A, Raizner A E, Waksman R, Leon M B. Implications of the Presence and Length of "Geographic Miss"on Restenosis and the Edge Phenomenon in the INHIBIT Trial. Am J Cardiol 91:1261-1265. 2003
  • Costantini C O, Lansky A J, Mintz G S, Shirai K, Dangas G, Mehran R, Fahy M, Stone G, Moses J, Leon M B . Intravascular Brachytherapy for Native Coronary Ostial In-Stent Restenotic Lesions. Journal of the American College of Cardiology. 41:1725-1731. 2003
  • Kumagai K, Nakashima H, Gondo N, Saku K. Antiarrhythmic Effects of JTV-519,a Novel Cardioprotective Drug,on Atrial Fibrillation/Flutter in a Canine Sterile Pericarditis Model. Journal of Cardiovascular Electrophysiology. 14:880-884. 2003
  • Takahashi Y,Iesaka Y,Takahashi A,Harada T,Mitsuhashi T, Shirota K,Kumagai K,Nuruki N,Shiraishi T,Nitta J,Ito H and The Ablation and Pacing Therapy Working Group. AV Nodal Ablation and Pacemaker Implantation Improves Hemodynamic Function in Atrial Fibrillation. Pacing and Clinical Electrophysiology. 26:1212-1217. 2003
  • Kawamura A, Miura S, Fujino M, Nishikawa H, Matsuo Y, Tanigawa H, Tomita S, Tsuchiya Y, Matsuo K, Saku K. CXCR3 Chemokine Receptor-Plasma IP10 Interaction in Patients With Coronary Artery Disease. Circulation Journal. 67:851-854. 2003
  • Koga T, Urata H, Inoue Y, Hoshino T, Okamoto T, Matsunaga A, Suzuki M, Miyazaki J, Ideishi M, Arakawa K, Saku K. Human Chymase Expression in a Mice Induces Mild Hypertension with Left Ventricular Hypertrophy. Hypertens Res. 26:759-768. 2003
  • Zhang B,Eto S,Fan P,Bian C,Shimoji E,Saito T,Saku K. Paraoxonase(Pon1)Q192R polymorphism and serum Pon1 activity in diabetic patients on maintenance hemodialysis. Clinical Nephrology. 60:257-265. 2003
  • Miura S, Saku K,Karnik S S. Molecular Analysis of the Structure and Function of the Angiotensin II Type1 Receptor. Hypertens Res. 26:937-943. 2003
  • Yamaguchi Y,Miura S,Urata H,Himeshima Y,Yamatsu K,Otsuka N,Nishida S,Saku K. The Effectiveness of a Multicomponent Program for Nutrition and Physical Activity Change in Clinical Setting:Short-term Effects of PACE+ Japan. International Journal of Sport and Health Science. 1(2)229-237. 2003
  • Sakata N, Takeuchi K, Noda K, Saku K, Tachikawa Y, Tashiro T, Nagai R, Horiuchi S. Calcification of the Medial Layer of the Internal Thoracic Artery in Diabetic Patients:Relevance of Glycoxidation. Journal of Vascular Research. 40:567-574. 2003
  • Yamaguchi Y, Miura S, Urata H, Himeshima Y, Yamatsu K, Otsuka N, Nishida S, Saku K. The Effectiveness of a Multicomponent Program for Nutrition and Physical Activity Change in Clinical Setting:Short-term Effects of PACE+Japan. International Journal of Sport and Health Science. 2:229-237. 2003
  • Costantini C O, Lansky A J, Mintz G S, Shirai K, Dangas G, Mehran R, Stone G, Leon M B. Usefulness of the angiographic pattern of in-stent restenosis in predicting the success of gamma vascular brachytherapy. Am J Cardiol. 92:1214-1217. 2003
  • Shirai K, Lansky A J, Mintz G S, Costantini C O, Fahy M, Mehran R, Dangas G, Moses J W, Stone G W, Leon M B. Comparison of the angiographic outcomes after beta versus gamma vascular brachytherapy for treatment of in-stent restenosis. Am J Cardiol. 92:1409-1413. 2003
  • Zhang B, Tanaka H, Shono N, Miura S, Kiyonaga A, Shindo M, Saku K. The I allele of the angiotensin -converting enzyme gene is associated with an increased percentage of slow-twitch type I fibers in human skeletal muscle. Clinical Genetics. 63:139-144. 2003
  • Miura S, Zhang J, Boros J, Karnik SS. TM2-TM7 interaction in coupling movement of transmembrane helices to activation of the angiotensin II type-1 receptor. J Biol Chem. 278: 3720-3725:2003.

2002年

  • OGAWA M, KUMAGAI K, GONDO N, MATSUMOTO N, SUYAMA K, SAKU K. Novel Electrophysiologic Parameter of Dispersion of Atrial Repolarization : Comparison of Different Atrial Pacing Methods. J Cardiovasc Electrophysiol. 13:110-117. 2002
  • Ogawa M, Hirose N, Ogimoto M, Matsuki H, Miki K, Kinoshita M, Koga A, Saku K. Chronic Benefical Effects of Type 1 Angiotensin II Receptor Antagonist in Patients with Chronic Hypoxemic Pulmonary Diseases. CARDIOLOGY. 97:111-112. 2002
  • Hideko Nakasima,Koichiro Kumagai,Hiroo Noguchi,HideakiTojo,Tomoo Yasuda and Keijiro Saku. Efficacy of Pulmonary Vein Isolation for Paroxysmal AtrialFibrillation. Med. Bull. Fukuoka Univ. 29:121-126. 2002
  • Nishikawa H, Miura S, Zhang B, Shimomura H, Arai H, Tsuchiya Y , Saku K. Pravastatin promotes coronary collateral circulation in patients with coronary artery disease. Coronary Artery Disease. 13:377-381. 2002
  • Miura S, Okamoto T, Via D P, Saku K. Transfer of Antisense Oligodeoxynucleotides Against Endothelin Receptors A and B Into Human Coronary Smooth Muscle Cells and Endothelial Cells by Apolipoprotein E Peptide-An in Vitro Study-.Circ J. 66:1054-1056. 2002
  • Aoki J, Taira A, Takanezawa Y, Kishi Y, Hama K, Kishimoto T, Mizuno K, Saku K, Taguchi R, Arai H. Serum Lysophosphatidic Acid Is Produced through Diverse Phospholipase Pathways. J Bio Chem. 277:48737-48744. 2002
  • Nomoto J, Oku K , Takao M, Tahara H, Inoue T, Handa K, Arakawa K, Saku K. Left Atrial Thrombus Formation in Patients with Nonvalvular Paroxysmal Atrial Fibrillation. Med.Bull.Fukuoka Univ. 29:187-194. 2002
  • Takase H,Sakiyama E,Noda K,Ono N,Saku K. The Administrative Management Division for Clinical Drug Trials(ACDT) at Fukuoka University Hospital. Med.Bull.Fukuoka Univ. 29:221-229. 2002
  • Nakashima H,Kumagai K,Tojo H,Yasuda T,Noguchi H,Matsumoto N, Saku K. Simultaneous catheter mapping of the pulmonary veins in focal atrial fibrillation:significance of rapid focal activation. Jpn Heart J.43:357-365. 2002
  • Nakashima H,Kumagai K,Noguchi H,Tojo H,Yasuda T,Saku K. Evaluation of the recurrence of atrial fibrillation after pulmonary venous ablation. J Cardiol. 40:87-94. 2002
  • Miura S, Tachibana K, Okamoto T, Saku K. In vitro transfer of antisense oligodeoxynucleotides into coronary endothelial cells by ultrasound. Biochem Biophys Res Commun. 298:587-590. 2002
  • Zhang B,Sakai T,Miura S,Kiyonaga A,Tanaka H,Shindo M,Saku K. Association of angiotensin -converting-enzyme gene polymorphism with the depressor response to mild exercise theraphy in patients with mild to moderate essential hypertension. Clinical Genetics. 62:328-333. 2002
  • Uehara Y,Urata H,Ideishi M,Arakawa K,Saku K. Chymase inhibition suppresses high-cholesterol diet-induced lipid accumulation in the hamster aorta. Cardiovascular Research. 55:870-876. 2002
  • Miura S, Karnik SS. Constitutive Activation of AngiotensinII Type-1 Receptor Althers the Orientation of Transmembrane Helix-2. J BiolChem. 277:24299-24305:2002.

2001年

  • Koichiro Kumagai, Hideaki Tojo, Hiroo Noguchi, Tomoo Yasuda, Hideki Tamari, Naomichi Matsumoto, Naoki Gondo, Hideko Nakashima and Keijiro Saku. Effects of Cavotricuspid Isthmus Catheter Ablation on Paroxysmal Atrial Fibrillation. Jpn Heart J. 42:79-89 2001
  • Naoki Gondo, Koichiro Kumagai, Hideko Nakashima, Keijiro Saku. Angiotensin II provokes cesium-induced ventricular tachyarrhythmias. Cardiovascular Research. 49:381-390 2001
  • BO ZHANG, PING FAN, HIROAKI TANAKA and KEIJIRO SAKU. Angiotensin II type-1 receptor antagonisut, CS-866, reduces blood pressure without affecting glucose/insulin metabolism in cholesterol-fed rabbits. British Journal of Biomedical Science 58:217-225 .2001